Septic Shock
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock [Phase 4]
Phase 4 clinical trial evaluating adjunctive corticosteroid therapy in critically ill patients with septic shock has completed.
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: Cellular Immunotherapy for Septic Shock [Phase 2]
Phase 2 clinical trial update on cellular immunotherapy for septic shock, sponsored by the Ottawa Hospital Research Institute. The condition…
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CLINICAL_TRIALS withdrawal · 2017-11-29Clinical Trial Update: NOrepinephrine and VasoprEssin Versus Norepinephrine aLone in Critically Ill Patients With Septic Shock [Phase 4]
A Phase 4 trial comparing norepinephrine alone versus norepinephrine plus vasopressin for septic shock was withdrawn.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Immune Reconstitution of Immunosuppressed Sepsis Patients [Phase 2]
Phase 2 trial investigating immune reconstitution in immunosuppressed sepsis patients was terminated.
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: Treatment of Septic Shock by Inhibiting Autodigestion and Preserving Gut Integrity With Enteric LB1148 [Phase 2]
Phase 2 trial update for LB1148 in septic shock; study terminated with posted results in 2017.
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CLINICAL_TRIALS research · 2017-11-17Clinical Trial Update: Early Versus Late CRRT in ACLF Patients With Septic Shock and AKI [NA]
This clinical trial update discusses a study comparing early versus late continuous renal replacement therapy in patients with acute-on-chro…
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CLINICAL_TRIALS withdrawal · 2017-11-06Clinical Trial Update: Midodrine During Recovery From Septic Shock [Phase 4]
Phase 4 trial evaluating midodrine for recovery from septic shock has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Phenylephrine in Septic Shock [Phase 2]
Phase 2 clinical trial of phenylephrine for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU
A completed clinical trial evaluates biomarkers to discriminate systemic inflammatory response syndrome from bacterial sepsis in ICU patient…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Plasma and Lung Tissue Concentrations of Linezolid in Septic Shock Patients
This clinical trial update reports measurements of linezolid concentrations in plasma and lung tissue from septic shock patients participati…
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock [Phase 4]
A Phase 4 trial comparing daily hydrocortisone doses (100 mg vs 200 mg) in septic shock and its association with hyperglycemia.
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis [Phase 3]
Phase 3 trial evaluating interferon-gamma for sepsis-induced immunoparalysis has completed.
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock [Phase 4]
Phase 4 trial update on piperacillin/tazobactam in critically ill patients with severe sepsis and septic shock; study completed.
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
A completed clinical trial evaluating central venous catheter colonisation in critically ill ICU patients, including individuals with sepsis…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Evaluation of Intestinal Brush Border Enzyme Function in Critically Ill Patients [NA]
A completed clinical trial evaluating intestinal brush border enzyme function in critically ill patients, including those with septic shock …
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CLINICAL_TRIALS trial_result · 2017-08-15Clinical Trial Update: Epidemiology of Sepsis in Turkish ICUs.
A completed clinical trial update examining the epidemiology of sepsis in Turkish intensive care units.
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CLINICAL_TRIALS research · 2017-08-09Clinical Trial Update: Medical Education for Sepsis Source Control and Antibiotics [NA]
This entry reports the completion of a clinical trial conducted by the Center for Sepsis Control and Care in Germany, focused on medical edu…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: Initiation of Hydrocortisone for the Treatment of Septic Shock [NA]
Completed clinical trial evaluating hydrocortisone for septic shock, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: Examination of ADMA Serum Level and DDAH II
A completed clinical trial examining ADMA serum levels and DDAH II in septic shock and sepsis.
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Upregulation of Alpha-1 Receptors Upon Septic Shock? [Phase 2, Phase 3]
A Phase 2/3 trial investigating upregulation of alpha-1 receptors in septic shock has been terminated.
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CLINICAL_TRIALS trial_result · 2017-06-15Clinical Trial Update: Prehospital Antibiotics Against Sepsis Trial [NA]
The trial evaluating prehospital antibiotics for sepsis has completed, sponsored by Amsterdam UMC and conducted at VUmc.
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CLINICAL_TRIALS research · 2017-06-15Clinical Trial Update: Dex on Microcirculation in SS-A Double-blinded Study [Phase 4]
An update on a Phase 4 double-blind trial investigating Dex on microcirculation in septic shock. The status of the study is currently unknow…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Statin Therapy in the Treatment of Sepsis [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial evaluated statin therapy for septic shock; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Activated Protein C and Corticosteroids for Human Septic Shock [Phase 3]
Phase 3 trial evaluating activated protein C in combination with corticosteroids for septic shock has completed.
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CLINICAL_TRIALS research · 2017-06-06Clinical Trial Update: Safety and Efficacy of Heparin Dosing Score Protocol for Polymyxin-B Hemoperfusion
Clinical trial update on the safety and efficacy of a heparin dosing score protocol during Polymyxin-B hemoperfusion for septic shock. The s…