Progressive Multiple Sclerosis
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Intrathecal Therapy With Monoclonal Antibodies in Progressive Multiple Sclerosis [Phase 2]
Clinical trial update indicating that a Phase 2 intrathecal monoclonal antibody therapy study in progressive multiple sclerosis has complete…
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CLINICAL_TRIALS trial_result · 2016-11-09Clinical Trial Update: A Pilot Study to Assess microRNA Biomarkers in Early and Later Stage Multiple Sclerosis
This update reports the results of a pilot study evaluating microRNA biomarkers in early and later stages of multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: Tear Analysis in the Diagnosis of Multiple Sclerosis [NA]
A study evaluating tear analysis as a diagnostic method for Primary Progressive Multiple Sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Access, Use and Opinions of Physiotherapy and Rehabilitation Services of People With Progressive MS in the UK.
A completed clinical trial assessing access, use, and opinions of physiotherapy and rehabilitation services for people with Progressive Mult…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: A First-in-human, Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple Sclerosis [Phase 1]
This first-in-human, single ascending-dose Phase 1 trial of GZ402668 in patients with progressive multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2016-03-30Clinical Trial Update: Autologous Mesenchymal Stem Cell (MSC) Transplantation in MS [Phase 1]
This Phase 1 study evaluates autologous mesenchymal stem cell transplantation in people with relapsing-remitting, secondary progressive, or …
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis [Phase 2, Phase 3]
A Phase 2/3 study evaluating rituximab for safety and efficacy in adults with primary progressive multiple sclerosis has completed, with res…
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CLINICAL_TRIALS trial_result · 2014-10-27Clinical Trial Update: Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS [Phase 1, Phase 2]
Clinical trial update evaluating the efficacy, safety and tolerability of andrographolide versus placebo in progressive forms of multiple sc…
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Safety Study of Natalizumab to Treat Multiple Sclerosis (MS) [Phase 1]
Phase 1 safety study of Natalizumab in multiple sclerosis has completed. The update highlights safety and tolerability data from this early-…
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Hydroxyurea in Primary Progressive Multiple Sclerosis [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating hydroxyurea for primary progressive multiple sclerosis was terminated (status: TERMINATED).
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CLINICAL_TRIALS withdrawal · 2013-09-16Clinical Trial Update: Dose Escalation Study to Evaluate the Penetration and Pharmacodynamic Effects of Baminercept in the Cerebrospinal Fluid (CSF)and Safety in Subjects With Secondary Progressive Multiple Sclerosis (SPMS) [Phase 1, Phase 2]
Biogen has withdrawn a dose-escalation Phase 1/2 trial of Baminercept in secondary progressive multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2013-07-11Clinical Trial Update: Cyclic Oral Methylprednisolone Trial in Multiple Sclerosis [Phase 2]
Phase 2 trial of cyclic oral methylprednisolone for progressive multiple sclerosis has completed enrollment/status.
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CLINICAL_TRIALS trial_result · 2012-12-07Clinical Trial Update: Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis [Phase 1, Phase 2]
This update covers safety data from a Phase 1/2 immunomodulating microparticle studied for primary and secondary progressive multiple sclero…
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CLINICAL_TRIALS research · 2012-11-28Clinical Trial Update: Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica [Phase 1, Phase 2]
This clinical trial update reports on the safety and efficacy evaluation of Umbilical Cord Mesenchymal Stem Cell Therapy for patients with P…
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CLINICAL_TRIALS research · 2012-11-15Clinical Trial Update: BetaPlus Survey - Observational Study to Assess Drug Adherence in Patients With Multiple Sclerosis After Conversion to Betaferon® by Using Elements of the BetaPlus Program
This completed observational trial evaluates adherence to Betaferon (interferon beta-1b) in patients with relapsing-remitting or secondary-p…
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CLINICAL_TRIALS research · 2012-11-01Clinical Trial Update: Portuguese Observational Survey to Assess Drug Adherence in Patients With Multiple Sclerosis After Conversion to Betaferon by Using Elements of the BetaPlus Program - Nurse Support, Auto-injectors
An observational Portuguese study evaluating adherence in multiple sclerosis patients after conversion to Betaferon (interferon beta-1b) via…
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: Natalizumab Treatment of Progressive Multiple Sclerosis [Phase 2]
A Phase 2 clinical trial evaluating Natalizumab for progressive multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2011-08-18Clinical Trial Update: AIMSPRO in the Treatment of Bladder Dysfunction in Secondary Progressive Multiple Sclerosis [Phase 2]
Phase 2 clinical trial update for AIMSPRO evaluating treatment of bladder dysfunction in patients with Secondary Progressive Multiple Sclero…
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CLINICAL_TRIALS trial_result · 2010-09-09Clinical Trial Update: A Study for Patients With Multiple Sclerosis [Phase 2, Phase 3]
A Phase 2/3 clinical trial for secondary progressive multiple sclerosis sponsored by Eli Lilly has been terminated.
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CLINICAL_TRIALS research · 2010-06-02Clinical Trial Update: A Study for Patients With Secondary Progressive Multiple Sclerosis [Phase 2, Phase 3]
A clinical trial update for a study in Secondary Progressive Multiple Sclerosis that enrolled patients in Phase 2 and Phase 3 and has comple…
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CLINICAL_TRIALS trial_result · 2010-02-08Clinical Trial Update: A Randomised Controlled Trial of Neuroprotection With Lamotrigine in Secondary Progressive Multiple Sclerosis [Phase 2]
Phase 2 randomized controlled trial evaluating lamotrigine for neuroprotection in Secondary Progressive Multiple Sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Study Evaluating Mitoxantrone in Multiple Sclerosis [Phase 3]
Phase 3 trial evaluating mitoxantrone in secondary progressive multiple sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2007-01-05Clinical Trial Update: Evaluation of Efficiency of Ritalin in Multiple Sclerosis (MS) Patients [Phase 1]
Phase 1 clinical trial update evaluating the effectiveness of Ritalin (methylphenidate) in patients with relapsing-remitting and primary pro…