Progressive Multiple Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Effect of Variance on Error Correction During Coupling [NA]
A completed Hasselt University clinical trial investigating how variance affects error correction during coupling in the context of Multiple…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus
A completed clinical trial evaluating upper-extremity function in advanced multiple sclerosis patients treated with ocrelizumab (Ocrevus) an…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Effect of Ocrelizumab on Cortical Lesion Accumulation in Patients With PPMS (ORATORIO-Cortical)
The ORATORIO-Cortical clinical trial update reports on the effect of ocrelizumab on cortical lesion accumulation in patients with primary pr…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: The Effects of In-phase Bilateral Exercise in People with Progressive Multiple Sclerosis [NA]
This clinical trial update summarizes a completed study evaluating the effects of in-phase bilateral exercise in people with progressive mul…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Multiple Sclerosis-Simvastatin Trial 2 [Phase 3]
Phase 3 trial evaluating simvastatin for secondary progressive multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies
A completed study evaluating changes in immunoglobulin levels in patients with relapsing multiple sclerosis treated with anti-CD20 therapies…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS) [Phase 3]
Phase 3 study exploring the mechanism of action of ocrelizumab and B-cell biology in relapsing and primary progressive multiple sclerosis; r…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) [Phase 4]
Phase 4 AMA-VACC trial results assess the immune response to SARS-CoV-2 modRNA vaccines in patients with secondary progressive multiple scle…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis
This clinical trial update reports the completion of a study evaluating the effectiveness and safety of Mayzent (fingolimod) in Chinese pati…
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Phase II Clinical Trial of OCH-NCNP1 [Phase 2]
Phase II clinical trial update for OCH-NCNP1 completed; study conditions include relapsing-remitting and secondary progressive multiple scle…
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CLINICAL_TRIALS trial_result · 2023-09-06Clinical Trial Update: Effect of Ocrelizumab on Brain Innate Immune Microglial Cells Activation in MS Using PET-MRI With 18F-DPA714 [Phase 3]
Phase 3 trial exploring ocrelizumab's effect on brain innate immune microglial activation in multiple sclerosis using PET-MRI.
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: A Trial of Bile Acid Supplementation in Patients With Multiple Sclerosis [Phase 1, Phase 2]
A combined Phase 1/2 trial evaluating bile acid supplementation in progressive multiple sclerosis has been completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis [Phase 1, Phase 2]
Clinical trial update for intranasal insulin in multiple sclerosis across Phase 1 and Phase 2 has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: G-EO Gait Rehabilitation Training in Progressive Multiple Sclerosis [NA]
Clinical trial update for G-EO Gait Rehabilitation Training in progressive multiple sclerosis; study completed with posted results in 2022.
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS [Phase 4]
Phase 4 trial assessing the effectiveness of fampridine in improving upper limb function in people with secondary progressive and primary pr…
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: Patient Research Cohort: Rapidly Evolving Multiple Sclerosis
A completed clinical trial update from Imperial College London on a patient research cohort for Relapsing-remitting and Secondary Progressiv…
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CLINICAL_TRIALS trial_result · 2020-12-24Clinical Trial Update: Dimethyl Fumarate Treatment of Primary Progressive Multiple Sclerosis [Phase 2]
Phase 2 clinical trial update for dimethyl fumarate in primary progressive multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2020-07-28Clinical Trial Update: Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis [Phase 2]
Phase 2 trial update on ibudilast in progressive multiple sclerosis assessing safety, tolerability, and activity.
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: A Study of NeuroVax™, a Therapeutic TCR Peptide Vaccine for SPMS of Multiple Sclerosis [Phase 2, Phase 3]
A clinical trial update for NeuroVax, a therapeutic TCR peptide vaccine being studied in secondary progressive and general multiple sclerosi…
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: A Study of Oxidative Pathways in MS Fatigue [Phase 2]
This Phase 2 clinical trial evaluated oxidative pathways related to fatigue in progressive multiple sclerosis, with results posted in Februa…
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: Autologous Mesenchymal Stromal Cells for Multiple Sclerosis [Phase 1, Phase 2]
Phase 1/2 trial assessing autologous mesenchymal stromal cells in relapsing-remitting and secondary progressive multiple sclerosis has compl…
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CLINICAL_TRIALS trial_result · 2019-11-06Clinical Trial Update: Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition [Phase 2]
Phase 2 trial evaluating estriol treatment for cognitive effects in multiple sclerosis patients.
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: Open-Label Study to Evaluate the Efficacy of ECP in Secondary Progressive Multiple Sclerosis [NA]
An open-label study evaluating the efficacy of ECP in secondary progressive multiple sclerosis has terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-23Clinical Trial Update: Comparison of Clinical Effects of Rituximab and Glatiramer Acetate in Secondary Progressive Multiple Sclerosis Patients [Phase 2, Phase 3]
A completed Phase 2/3 trial comparing rituximab to glatiramer acetate in secondary progressive multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2019-03-07Clinical Trial Update: Clinical Trial of Idebenone in Primary Progressive Multiple Sclerosis (IPPoMS) [Phase 1, Phase 2]
Phase 1/2 clinical trial of idebenone for primary progressive multiple sclerosis has completed with results posted.