Richter Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS [Phase 1, Phase 2]
Clinical trial update on the Phase 1/2 study of the duvelisib and venetoclax combination in relapsed or refractory Chronic Lymphocytic Leuke…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating ALX148 in combination with Rituximab and Lenalidomide for various B-cell non-Hodgkin lymphomas, with the trial …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome [Phase 2]
Phase 2 clinical trial evaluating a triple-drug regimen (atezolizumab, obinutuzumab, and venetoclax) for chronic lymphocytic leukemia, small…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies [Phase 1]
A Phase 1 clinical trial evaluates PRT2527 as a standalone therapy and in combination with zanubrutinib or venetoclax for relapsed/refractor…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Evaluation of Treatment by Glofitamab in Combination With Rituximab or Obinutuzumab Plus CHOP in Patients With RIchter Syndrome [Phase 2]
Phase 2 clinical trial evaluating glofitamab in combination with rituximab or obinutuzumab plus CHOP for Richter syndrome; recruitment is on…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: A Study to Evaluate Efficacy & Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Richter's Syndrome; [Phase 2]
A Phase 2 study evaluating the efficacy and safety of a triple therapy with obinutuzumab, ibrutinib, and venetoclax in Richter's Syndrome ha…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma [Phase 1]
A Phase 1 study evaluating the safety and preliminary efficacy of the combination of duvelisib and nivolumab in patients with Richter syndro…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Study of Ibrutinib & Obinutuzumab With/Without CHOP for Richter's Transformation or Richter's Syndrome Patients [Phase 2]
Phase 2 trial of ibrutinib with/without obinutuzumab +/- CHOP for Richter's Transformation/Richter's Syndrome was terminated; results posted…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: BLINAtumomab After R-CHOP Debulking Therapy for Patients With Richter Transformation [Phase 2]
Phase 2 clinical trial evaluating BLINAtumomab after R-CHOP debulking therapy for Richter transformation has completed.
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas [Phase 2]
Phase 2 trial of pembrolizumab alone or with idelalisib or ibrutinib in relapsed/refractory chronic lymphocytic leukemia or various low-grad…
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CLINICAL_TRIALS trial_result · 2022-09-10Clinical Trial Update: ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia [Phase 1, Phase 2]
ACP-196 (acalabrutinib), a BTK inhibitor, is being studied in Phase 1/2 trials for chronic lymphocytic leukemia, Richter's syndrome, small l…
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CLINICAL_TRIALS trial_result · 2020-06-24Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma or Relapsed or Refractory Richter Syndrome (MK-3475-170/KEYNOTE-170) [Phase 2]
Phase 2 study of pembrolizumab in relapsed/refractory primary mediastinal large B-cell lymphoma and Richter syndrome has completed with post…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Allogeneic Stem Cell Transplant for CLL [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation for chronic lymphocytic leukemia and related diseas…
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Study of Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone (CHOP) With Ofatumumab in Patients With Richter's Syndrome [Phase 2]
A Phase 2 trial evaluating CHOP chemotherapy with ofatumumab for Richter's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2015-04-16Clinical Trial Update: Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLL [Phase 1, Phase 2]
Phase 1/2 trial results evaluate the efficacy and safety of combining ibrutinib (PCI-32765) with ofatumumab in B-cell chronic lymphocytic le…
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CLINICAL_TRIALS trial_result · 2013-11-26Clinical Trial Update: Oxaliplatin, Fludarabine, Cytarabine, and Rituximab in Patients With Richter's Transformation and Leukemias [Phase 1, Phase 2]
Phase 1/2 study evaluating a regimen of oxaliplatin, fludarabine, cytarabine, and rituximab in patients with Richter's syndrome and leukemia…
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders [Phase 1, Phase 2]
Phase 1/2 trial of VNP40101M for Richter syndrome and refractory/relapsed chronic lymphocytic leukemia or other lymphoproliferative disorder…