Rhabdomyosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma [Phase 1]
This is a Phase 1 clinical trial evaluating FGFR4 CAR T cells in children and young adults with recurrent or refractory rhabdomyosarcoma; th…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
An NCI-sponsored Phase 1/2 trial of vincristine and temozolomide with PEN-866 in adolescents and young adults with relapsed or refractory so…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors [Phase 1]
Phase 1 trial evaluating IL-15 armored glypican-3–specific CAR-T cells for solid tumors, including hepatocellular carcinoma and several pedi…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas [Phase 1]
Phase 1 study evaluating CD45RA+ depleted haploidentical stem cell transplantation in children with relapsed or refractory solid tumors and …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors [Phase 1]
This is an update on a Phase 1 trial of interleukin-15 armored GPC3-specific CAR-T cells for pediatric solid tumors, with results posted and…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma [Phase 1]
A completed Phase I clinical trial evaluated the combination of olaparib and temozolomide in patients with Ewing sarcoma and rhabdomyosarcom…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma [Phase 2]
A Phase 2 trial of nab-paclitaxel plus gemcitabine for recurrent or refractory sarcoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer [Phase 1, Phase 2]
This document details an ongoing Phase 1/2 clinical trial evaluating cobolimab in combination with dostarlimab in pediatric and young adult …
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma [Phase 2]
This entry reports on a Phase 2 clinical trial evaluating upfront window therapy with irinotecan and carboplatin for newly diagnosed interme…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors [Phase 1]
Phase 1 trial evaluating cytokine-armored GPC3-targeted CAR-T cells in adults with solid tumors, including hepatocellular carcinoma; the stu…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant after chemotherapy for recurrent or refractory high-risk solid tumors in pediatric and…
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Proton Radiation Therapy (RT) for the Treatment of Pediatric Rhabdomyosarcoma [NA]
This clinical trial update notes the completion of a pediatric rhabdomyosarcoma study evaluating proton radiation therapy, with results post…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor [Phase 1]
Phase 1 trial evaluating a conditioning regimen of busulfan, melphalan, and topotecan hydrochloride followed by stem cell transplantation in…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors [Phase 2]
Phase 2 trial update of haploidentical transplantation with donor natural killer cells for solid tumors; the study was terminated and result…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Radiation Therapy to Treat Musculoskeletal Tumors [Phase 2]
A Phase 2 clinical trial evaluating radiation therapy for musculoskeletal tumors has posted results (as of 2025-03-06). The study is current…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma [Phase 1, Phase 2]
A phase 1/2 trial evaluating the combination of prexasertib, irinotecan, and temozolomide in Desmoplastic Small Round Cell Tumor and rhabdom…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating heated intraperitoneal chemotherapy with doxorubicin and cisplatin for pediatric abdominal/pelvic tu…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases [NA]
Clinical trial update indicates completion of a study evaluating intensity-modulated radiation therapy in younger patients with lung metasta…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma [Phase 3]
Phase 3 trial evaluating adding temsirolimus to combination chemotherapy for intermediate-risk rhabdomyosarcoma; results posted in 2024 and …
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma [Phase 3]
Phase 3 trial examining combination chemotherapy with or without temsirolimus in intermediate-risk rhabdomyosarcoma; active/not recruiting w…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…