Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course Radiotherapy [Phase 2]
A Phase 2 clinical trial is evaluating whether Bergmann Enema can prevent acute radiation enteritis/rectal injury in rectal cancer patients …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study evaluating LY3214996 with cetuximab, alone or in combination with abemaciclib, for unres…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer [Phase 2]
Phase 2 trial evaluating simultaneous integrated boost radiotherapy (SIB-RT) with CAPOX chemotherapy and a PD-1 inhibitor for high-risk rect…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC [Phase 2]
Phase 2 trial evaluating neoadjuvant therapy for locally advanced rectal cancer using radiotherapy with CAPOX and immune agents iparomlimab …
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers [NA]
An update on a clinical trial evaluating reduced surgical resection extent after neoadjuvant therapy for locally advanced upper rectal and r…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer
A registered clinical trial evaluating a dynamic multi-omics integration model to predict neoadjuvant therapy response in locally advanced r…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer [NA]
A clinical trial evaluating postoperative anal function after Parks versus Bacon techniques for low rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: RCT of Mobile Apps & FitBit v. Usual Care [NA]
An ongoing randomized trial compares a mobile apps plus FitBit intervention to usual care in patients with pancreatic, gastric, liver, colon…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Survivor Choices for Eating and Drinking - Colorectal Cancer [NA]
The UCSF-sponsored clinical trial on Survivor Choices for Eating and Drinking for colorectal cancer has completed.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC [Phase 2]
Phase 2 trial comparing short-course radiotherapy versus long-course radiotherapy followed by a PD-L1 inhibitor plus CAPEOX as total neoadju…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer [NA]
This ClinicalTrials.gov update describes a study evaluating a watch-and-wait strategy in distal rectal cancer that is dMMR/MSI-H and has bee…
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CLINICAL_TRIALS other · 2025-12-11Clinical Trial Update: PD-1 + FOLFOXIRI vs CAPOX as Total Neoadjuvant Therapy for pMMR Low Rectal Cancer [Phase 3]
A Phase 3 trial comparing PD-1–based total neoadjuvant therapy (PD-1 inhibitor plus FOLFOXIRI) versus CAPOX for microsatellite-stable locall…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer [Phase 2]
Phase 2 trial update evaluating short-course radiation with TASOX (TAS102 plus oxaliplatin) chemotherapy in operable rectal cancer, with res…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC) [NA]
A clinical trial is evaluating a NEAAR medical food in combination with total neoadjuvant therapy for locally advanced rectal cancer; the st…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Adaptive Radiation Boost for Rectal Cancer [Phase 1]
A Phase 1 clinical trial evaluating an adaptive radiation boost approach for rectal cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer
A clinical trial evaluating the use of multimodal MRI to grade histology and assess prognosis in rectal cancer; status is not yet recruiting…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer
The document updates a clinical trial evaluating neoadjuvant dostarlimab for dMMR/MSI-H locally advanced rectal cancer and notes that the st…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Prevention of Colorectal Cancer Through Multiomics Blood Testing
Completed clinical trial evaluating a multiomics blood test for colorectal cancer prevention; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Comparison of Six Different Machine Learning Methods With Traditional Model for Low Anterior Resection Syndrome After Minimally Invasive Surgery for Rectal Cancer -- Development and External Validation of a Nomogram : A Dual-center Cohort Study
This dual-center cohort study evaluates six machine-learning methods against a traditional model for predicting Low Anterior Resection Syndr…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer [NA]
A recruiting study comparing conventional neoadjuvant therapy to total neoadjuvant therapy in older adults with locally advanced rectal canc…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum [NA]
Clinical trial evaluating the safety and efficacy of ischemic preconditioning by embolization of the inferior mesenteric artery in surgery f…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer [Phase 2]
The Phase 2 CRAFTER trial (NCT05358704) evaluating preoperative chemoradiation with the FOLFOXIRI regimen for rectal cancer has been suspend…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery [NA]
The clinical trial investigating endovascular embolization of the inferior mesenteric artery to improve colonic perfusion before rectal or s…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Response-adapted Total Neoadjuvant Therapy Guided by Induction Chemotherapy in Early- and Intermediate-risk Low Rectal Cancer for Implementation of a Watch-and-wait Strategy
This clinical trial evaluates response-adapted total neoadjuvant therapy guided by induction chemotherapy for early- and intermediate-risk l…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique) [NA]
A clinical trial investigating whether preserving the superior left colic artery improves vascularization of the descending colon prior to c…