Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer [Phase 2]
This source describes a single-center Phase II study evaluating the efficacy and safety of SCRT+CAPOX+serplulimab+bevacizumab for microsatel…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Exploring the Predictive Effect of Intestinal and Oral Microbiota on the Efficacy of Neoadjuvant Radiotherapy and Chemotherapy for Locally Advanced Rectal Cancer Based on Machine Learning
This clinical trial update describes a completed study evaluating whether intestinal and oral microbiota can predict the response to neoadju…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Postoperative Complications After Neoadjuvant Chemoradiotherapy or Short-course Radiotherapy and Total Neoadjuvant Treatment: a Multicentric Retrospective Cohort Study
A multicenter retrospective cohort study examining postoperative complications after various neoadjuvant therapies for locally advanced rect…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Reinforced Versus Conventional Anastomosis in Laparoscopic Low Rectal Cancer Resection: A Comparative Study [NA]
A clinical trial evaluating reinforced versus conventional anastomosis in laparoscopic low rectal cancer surgery is currently enrolling by i…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Effect of Individualized Catheter Management on Early Removal After Rectal Cancer Surgery [NA]
Clinical trial investigating whether individualized catheter management can enable earlier removal after rectal cancer surgery; currently no…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Sample Collection for Ongoing Research and Product Evaluation Study
Natera reports an ongoing study update focused on sample collection for ongoing research and product evaluation; the trial is currently recr…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer [Phase 3]
A Phase 3 non-inferiority trial evaluating preoperative chemotherapy without pelvic irradiation for rectal cancer; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial is evaluating short-course radiotherapy plus chemotherapy with Iparomlimab and Tuvonralimab for locally advanced rectal canc…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: PeLear CCC: Proyecto Latino Contra Cancer Colorrectal [NA]
The PeLear CCC colorectal cancer trial conducted by the University of North Carolina completed and posted results on January 14, 2026.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer [Phase 2]
A Phase 2 trial evaluating radiation therapy and fluorouracil with or without additional chemotherapy, followed by surgery, for patients wit…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer [Phase 2, Phase 3]
This entry reports ongoing Phase 2/Phase 3 clinical trials evaluating neoadjuvant chemoradiotherapy combined with immunotherapy for locally …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Selective Total Mesorectal Excision Based on Intra-Operative Frozen Section From Local Excision in Rectal Cancer Undergoing Neoadjuvant Chemoradiotherapy [NA]
A clinical trial investigates using intra-operative frozen section to guide selective total mesorectal excision after local excision in rect…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients [Phase 3]
A Phase 3 clinical trial update comparing standard-dose versus high-dose radiotherapy with chemoradiotherapy for rectal preservation in rect…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer [Phase 2]
This clinical trial update describes a Phase 2 study of dostarlimab for untreated dMMR/MSI-H locally advanced rectal cancer, which is curren…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Curative Chemoradiation of Low Rectal Cancer
Clinical trial update indicates a curative chemoradiation approach for low rectal cancer is currently active but not recruiting, sponsored b…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases [Phase 2, Phase 3]
This document notes a Phase 2/3 clinical trial examining IP-001 injected into thermally ablated hepatic tumors in patients with colorectal l…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: MRI T1 Relaxation Time in Rectal Cancer
This completed trial evaluated MRI T1 relaxation time as an imaging biomarker in rectal cancer, including locally advanced disease. It prese…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of Daily Step Count and Treatment Response in Rectal Cancer (STEP-R)
An ongoing trial (STEP-R) at Gazi University is evaluating whether daily step count, measured via a smart watch, correlates with treatment r…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal Cancer [Phase 2]
Phase 2 trial assessing node-sparing short-course radiation with capecitabine and PD-1/CTLA-4 inhibitors for microsatellite-stable early rec…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients [Phase 2]
This document notes that a Phase 2 trial investigating nivolumab with the FOLFOX regimen after chemoradiation in rectal cancer is active but…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluated neoadjuvant chemoradiation therapy combined with immunotherapy for microsatellite-stable ultra-low rec…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Evaluating the Impact of GLP-1 Receptor Agonists With Total Neoadjuvant Therapy in Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating GLP-1 receptor agonists in combination with total neoadjuvant therapy for rectal cancer; the study is not …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Target-specific immunoPET Imaging of Digestive System Carcinoma [NA]
A recruiting clinical trial evaluating a target-specific immunoPET imaging agent for digestive system carcinomas across multiple digestive c…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Irinotecan Liposome Plus Capecitabine and Enronsubemab Combined With Short-course Radiotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer [Phase 2]
Phase 2 neoadjuvant trial combining liposomal irinotecan and capecitabine with enronsubemab plus short-course radiotherapy for locally advan…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)
This clinical trial update describes the DIAMOND study, which analyzes the distribution of metastatic lymph nodes in colorectal cancer patie…