Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of Botensilimab and Balstilimab for microsatellite-stable rectal cancer and locally advanc…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer [NA]
A ClinicalTrials.gov entry describes a study evaluating whether Kegel exercises combined with biofeedback therapy can improve bowel function…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue [Phase 2]
A Phase II single-arm study examines high-bioavailability curcumin as part of neoadjuvant chemoradiotherapy for rectal cancer, with integrat…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Neoadjuvant Long-course Chemoradiotherapy Followed by Immunotherapy for Locally Advanced Mid-low Rectal Cancer [Phase 2]
A Phase 2 trial of neoadjuvant long-course chemoradiotherapy followed by immunotherapy for locally advanced mid-low rectal cancer has comple…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET) [Phase 2]
A Phase II basket trial is evaluating Zanidatamab in combination with Tislelizumab for HER2-positive gastrointestinal tumors, including rect…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial [NA]
The PROPEL Trial is a clinical study evaluating preoperative exercise and nutritional optimization to improve perioperative outcomes for pat…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Clinical Study on the Safety and Relationship of Sintilimab Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma [Phase 2]
Phase 2 clinical study evaluating the safety of combining sintilimab with chemotherapy as neoadjuvant treatment for locally advanced rectal …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Extra-Peritoneal Tunneling Versus Conventional Drain Fixation After Anterior or Low Anterior Resection [NA]
Clinical trial comparing extra-peritoneal tunneling versus conventional drain fixation after anterior or low anterior resection; the study s…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a triple combination of encorafenib, cetuximab, and nivolumab in patients with microsatellite-stabl…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Colon Neoadjuvant FOLFOXIRI Study [Phase 2]
This update describes a Phase 2 trial evaluating neoadjuvant FOLFOXIRI therapy for rectal cancer, sponsored by the Chinese University of Hon…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of Dostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in China [Phase 2]
GlaxoSmithKline is conducting a Phase 2 study of dostarlimab (Jemperli) in participants with untreated locally advanced rectal cancer in Chi…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: FOLFOXIRI With or Without Intensification for Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating the FOLFOXIRI chemotherapy regimen with or without intensification for rectal cancer; the study is current…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer [Phase 1, Phase 2]
A ClinicalTrials.gov entry describes the 3B-FOLFOX study, a Phase 1/2 trial of FOLFOX and Bevacizumab combined with Botensilimab and Balstil…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer [EARLY_Phase 1]
Update on an early-phase trial of a copper-64 labeled M5A antibody in combination with standard chemotherapy and radiotherapy for locally ad…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer [EARLY_Phase 1]
This early-phase trial evaluates active surveillance with chemotherapy before surgery for stage II–III rectal cancer and is currently recrui…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Genomic Structural Variation in Cancer Susceptibility
This clinical trial update discusses ongoing research on genomic structural variation in cancer susceptibility and lists several cancer cond…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Clinical trial SYNERGY-AI is an AI-based precision oncology matching and registry study sponsored by Massive Bio, currently recruiting acros…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Efficacy and Safety of the CG-100 Intraluminal Bypass Device [NA]
The document provides a trial update for the CG-100 intraluminal bypass device, noting that recruitment is ongoing for rectal cancer-related…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Vaginal Dilator Therapy After Pelvic Radiation [NA]
Duke University is conducting a trial to evaluate vaginal dilator therapy after pelvic radiation. The study is not yet recruiting and target…
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CLINICAL_TRIALS other · 2025-10-09Clinical Trial Update: Total Neoadjuvant Therapy With PD-1 for Locally Advcancer Rectal Cancer [Phase 2]
Phase 2 trial evaluating total neoadjuvant therapy including a PD-1 inhibitor for locally advanced rectal cancer is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer [NA]
This completed clinical trial compared a collagen implant (biological mesh) with a gracilis muscle flap for reconstruction of the pelvic flo…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Study of Intramural Spread Pattern in Low Rectal Cancer.
Clinical trial update for a study on intramural spread patterns in low rectal cancer; the study status is completed.
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC [Phase 2]
A Phase 2 trial in locally advanced rectal cancer is testing total neoadjuvant therapy with short-course radiotherapy followed by CAPOX and …
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: SCRT in TNT With or Without Chlorophyllin [Phase 2]
Phase 2 clinical trial update evaluating short-course radiotherapy in total neoadjuvant therapy for rectal cancer. The study investigates ou…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Rectal Cancer CTC Trial [NA]
A clinical trial conducted by University Hospital Ostrava is investigating circulating tumor cells in patients with rectal cancer and is cur…