Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors [Phase 1, Phase 2]
This entry describes a Phase 1/2 study evaluating the safety, pharmacokinetics, and preliminary effectiveness of GSK4418959 in participants …
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Effect of ICCAUT Strategy on Postoperative Urinary Dysfunction After Radical Rectal Cancer Surgery [NA]
A completed clinical trial evaluating the ICCAUT strategy for postoperative urinary dysfunction after radical rectal cancer surgery.
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Robotic Natural Orifice Specimen Extraction Surgery Compared to Robotic Assisted Surgery for Median Rectal Cancer [NA]
This update reports the completion of a clinical trial comparing robotic natural orifice specimen extraction surgery to robotic-assisted sur…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Prospective Single-center Randomized Controlled Trial of Robotic Surgery With Transrectal Resection Specimens (NOSES-IV) and Traditional Assisted Robotic Surgery for the Treatment of High Rectal and Sigmoid Colon Cancer [NA]
A prospective, single-center randomized trial compares NOSES-IV robotic surgery with transrectal specimens to traditional assisted robotic s…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer [NA]
Clinical trial update on the SMART trial evaluating modified single-stapled anastomosis in laparoscopic or robotic low anterior resection fo…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer [Phase 1]
Phase 1 clinical trial evaluating a triple combination of regorafenib, ipilimumab, and nivolumab in chemotherapy-resistant microsatellite-st…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer [Phase 3]
A Phase 3 clinical trial is investigating modulated electro-hyperthermia combined with multimodal therapy for locally advanced rectal cancer…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery [NA]
Completed clinical trial comparing transversus abdominis plane (TAP) block to epidural anesthesia for pain management in colorectal surgery;…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer [Phase 2]
Phase 2 INNATE trial evaluating immunotherapy during neoadjuvant therapy for locally advanced rectal cancer is currently active but not recr…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal Cancer
This ClinicalTrials.gov entry describes a study evaluating amide proton transfer-weighted imaging to predict pathological complete response …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating total neoadjuvant therapy with modified FOLFOX (5-fluorouracil, leucovorin, oxaliplatin) and short-cours…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function [NA]
A clinical trial is evaluating whether a probiotic intervention affects gut microbiota and bowel function in patients with Rectal cancer; th…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer [NA]
An ongoing single-arm multicenter trial is evaluating preoperative neoadjuvant mFOLFOX6 chemotherapy in combination with a PD-1 monoclonal a…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer [NA]
A clinical trial from Peking University Cancer Hospital & Institute is exploring autologous probiotic transplantation in rectal cancer patie…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable) [NA]
KU Leuven is conducting a clinical trial to develop personalized care pathways for bowel symptoms in rectal cancer patients, including Low A…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: F-Tryptophan PET/CT in Human Cancers [Phase 1]
A Phase 1 study evaluating F-Tryptophan PET/CT imaging across several cancers (intracranial glioma, metastatic brain tumor, breast cancer, n…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma
This clinical trial update from Sohag University outlines a study design focused on patterns of treatment and outcomes for locally advanced …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Integrated Cancer Repository for Cancer Research
A University of Nebraska-sponsored clinical trial update indicates the Integrated Cancer Repository for Cancer Research is currently recruit…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial [Phase 1, Phase 2]
Clinical STOPTRAFFIC-1 trial evaluates SX-682 in combination with Nivolumab for RAS-mutated, MSS unresectable or metastatic colorectal cance…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Postoperative Outcomes of Single-stapled Anastomosis Combined With Transanal Natural Orifice Specimen Extraction
This clinical trial update describes a study evaluating a single-stapled anastomosis with transanal natural-orifice specimen extraction in r…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Leucine Plus Radiochemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer [NA]
This clinical trial investigates adding leucine to radiochemotherapy as neoadjuvant treatment for locally advanced rectal cancer. Recruitmen…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer [Phase 2]
Phase 2 trial comparing oral cryotherapy with acupressure/acupuncture versus oral cryotherapy alone to prevent oxaliplatin-induced periphera…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer （SPARK） [Phase 2]
Phase 2 SPARK trial evaluating total neoadjuvant therapy for pMMR/MSS locally advanced rectal cancer using short-course radiotherapy followe…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Development and Validation of a Post-operative Risk Of Local Recurrence Model Integrating Serology and Evalution (PROMISE) in Local Advanced Rectal Cancer Receiving Neoadjuvant Therapy: a Multicenter Study
A completed multicenter study validating PROMISE, a postoperative risk model that integrates serology and clinical evaluation to predict loc…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: ctDNA-Informed Management of Early-Stage Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating ctDNA-informed management for early-stage rectal cancer; the study is currently not yet recruiting.