Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing HPV vaccine PRGN-2009 alone or in combination with anti-PD-L1/TGF-β trap M7824 in several HPV-associated …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Organ Preservation in Rectal Cancer by Dose Escalated MR Guided Adaptive Radiotherapy [Phase 2]
A Phase 2 clinical trial is evaluating dose-escalated MR-guided adaptive radiotherapy for organ preservation in rectal cancer and is current…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: No Surgery Trial / Two Dose-escalation Strategies [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating two dose-escalation strategies for rectal cancer with no surgery, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in High-Risk Locally Advanced Rectal Cancer [Phase 3]
This Phase 3 trial compares long-course radiotherapy followed by total neoadjuvant therapy with immunotherapy versus long-course radiotherap…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer [NA]
A clinical trial update describing the use of ultrasound and photoacoustic imaging to improve differential diagnosis of rectal cancer; the s…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal Cancer [Phase 2]
Clinical trial update for a Phase 2 study combining preoperative sequential short-course radiation therapy with the FOLFOX regimen in locall…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Phase II Prospective Study of Maastro Applicator Brachytherapy for Rectal Cancer [Phase 2]
This update covers a Phase II prospective study evaluating the Maastro Applicator Brachytherapy for rectal cancer. The study is currently no…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating adding epacadostat to preoperative chemoradiation for locally advanced rectal cancer; recruitment i…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial protocol evaluating short-course radiotherapy combined with chemotherapy and immunotherapy for mid-low locally advanced rect…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Intraoperative Assessment of Distal Resection Margins Using Frozen Section in Mid and Low Rectal Cancer Surgery [NA]
This clinical trial evaluated intraoperative frozen-section assessment of distal resection margins during mid and low rectal cancer surgery;…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study [Phase 2]
Phase 2 results of the TABAsCO study evaluating TAS-102 in combination with irinotecan and bevacizumab for pre-treated metastatic or unresec…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Postoperative Results and Outcomes in Surgical Pelvic Exenteration
Clinical trial update on postoperative results and outcomes in pelvic exenteration for rectal cancer; enrollment is by invitation.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial) [NA]
The FEED Trial is investigating a high-fermented food intervention in patients with rectal cancer (also listed for non-small cell lung cance…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating short-course radiotherapy with tumor-draining lymph node preservation followed by a PD-1 inhibitor in pati…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy [Phase 2]
This is a Phase 2 clinical trial evaluating the combination of Botensilimab and Balstilimab for colorectal cancer with detectable ctDNA afte…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer [Phase 1]
A Phase 1 clinical trial update for SMART TNT in the conservative management of locally advanced rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal
This entry describes a clinical trial evaluating a novel camera to inspect the bowel after removal of polyps or tumors; the study status is …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma [Phase 2, Phase 3]
Clinical trial evaluating tailored management of locally advanced rectal cancer, currently in Phase 2/3 and recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery [NA]
A clinical trial is evaluating a machine learning-based surgical guidance system for robot-assisted rectal cancer surgery. The study is curr…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Improving Care for Rural Patients With Solid Tumors [NA]
Clinical trial update from University of Colorado focusing on improving care for rural patients with solid tumors; the study is currently re…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Evaluation of Gynecological and Sexual Sequelae
The trial investigates gynecological and sexual sequelae in rectal cancer patients. Recruitment has not yet started.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study) [Phase 2]
A Phase 2 trial (FIRM02) is evaluating neoadjuvant mFOLFOX6 chemotherapy combined with an anti-PD-1 therapy in MSS/pMMR locally advanced rec…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: CAPOX and Bevacizumab With or Without Primary Tumor Radiotherapy and Iparomlimab and Tuvonralimab as First-line Treatment for RAS-Mutant/MSS Metastatic Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating CAPOX and Bevacizumab with or without primary tumor radiotherapy, plus iparomlimab and tuvonralimab, as …
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: XELOX Plus DoSTARlimab Versus XELOX Alone as Consolidation Treatment After Standard Chemoradiation in pMMR/MSS or MSI-Low Locally Advanced Rectal Cancer (LARC) Patients [Phase 2]
Phase 2 clinical trial evaluating XELOX plus Dostarlimab vs XELOX alone as consolidation after chemoradiation in pMMR/MSS or MSI-Low locally…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer [Phase 3]
This Phase 3 trial compares preoperative FOLFOX chemotherapy to postoperative risk-adapted chemotherapy in patients with locally advanced re…