Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: ONCO-RET: Supervised Resistance Training During Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer [NA]
This clinical trial update covers the ONCO-RET study, which investigates supervised resistance training during total neoadjuvant therapy for…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating FAPI-PET/CT imaging to predict pathological complete response after neoadjuvant chemoradiotherapy in patie…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC [Phase 2]
Phase 2 trial evaluating short-course radiotherapy in total neoadjuvant therapy combined with Enlonstobart for pMMR locally advanced rectal …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial evaluating low-dose radiotherapy to enhance Pucotenlimab plus CAPEOX in mismatch repair-proficient locally advanced rectal can…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of Tucatinib and Trastuzumab in People With Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating the combination of tucatinib and trastuzumab in rectal cancer patients is currently recruiting, includin…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Long-term Outcomes and Risk Factors of Local Re-Recurrence in Patients
This clinical trial update reports long-term outcomes and identifies risk factors for local recurrence after treatment of rectal cancer.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer [Phase 3]
A Phase 3 clinical trial is evaluating neoadjuvant therapy with mFOLFOXIRI plus bevacizumab in patients with high-risk locally advanced rect…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION) [Phase 3]
A Phase 3 trial (UNION) is evaluating short-course radiotherapy followed by neoadjuvant chemotherapy and camrelizumab for locally advanced r…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide [EARLY_Phase 1]
First-in-human Phase 1 PET imaging study of the 18F-αvβ6-binding peptide, a radiotracer targeting αvβ6, is active but not currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression [Phase 2]
Phase 2 trial of neoadjuvant mFOLFOX plus Alvenor for locally advanced rectal cancer. The study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS withdrawal · 2026-02-25Clinical Trial Update: A Trial of Regorafenib Plus Lorigerlimab in Patients With Locally Recurrent or Regrowing pMMR/MSS Localized Rectal Cancer [Phase 2]
ClinicalTrials.gov entry notes that a Phase 2 trial of regorafenib plus lorigerlimab for locally recurrent or regrowing pMMR/MSS localized r…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery [NA]
An ongoing Sun Yat-sen University clinical trial is evaluating pelvic floor peritoneal closure to prevent postoperative ileus after middle-t…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: ColoSeal™ ICD System Anastomotic Protection Pivotal Study [NA]
Clinical trial update for the ColoSeal ICD System Anastomotic Protection pivotal study in rectal cancer surgery, currently not yet recruitin…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers [Phase 1]
The first-in-human Phase 1 study of ATX-559, an oral DHX9 inhibitor from Accent Therapeutics, has been terminated; the trial included patien…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: INVESTIGATION OF THE ANTI-NEOPLASTIC EFFECT OF TRISHUL (AYURVEDIC AGENT) ON TUMOUR REGRESSION OF RECTAL CANCER- A PILOT STUDY [Phase 2]
A Phase 2 pilot clinical trial is investigating the anti-tumor effects of the Ayurvedic agent Trishul on rectal cancer, with recruitment not…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Pilot Study of Individualized Comprehensive Rehabilitation in Patients With Colorectal Cancer [NA]
A pilot study evaluating individualized comprehensive rehabilitation for colorectal cancer patients has completed; no results are provided i…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Quality Of Life In Colorectal Cancer Survivors [NA]
A clinical trial assessing quality of life in colorectal cancer survivors is currently recruiting at the Institute of Oncology Ljubljana.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of a mesothelin-targeting logic-gated CAR T therapy in adults with solid tumors …
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery
A completed clinical trial evaluating indocyanine green fluorescence angiography to aid intraoperative assessment during laparoscopic sigmoi…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: MRA Diameter as a Predictor for LLN Metastasis in Rectal Cancer.
A completed clinical trial (NCT07419516) investigates whether MRA diameter can predict lateral lymph node metastasis in rectal cancer.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations
This clinical trial update describes an ongoing study on rectal cancer examining quality of life, treatment modalities, and patient treatmen…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Advanced Endoscopic Resections for Rectal Neoplasms
This clinical trial update outlines advanced endoscopic resection approaches for rectal neoplasms, and the study is currently not yet recrui…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer [Phase 3]
This ClinicalTrials.gov entry describes a Phase 3 study evaluating early erectile rehabilitation with sildenafil after radiotherapy and proc…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer [Phase 1]
This clinical trial update indicates that Akamis Bio is recruiting for a Phase 1 study of NG-350A in combination with chemoradiotherapy for …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: The Surveillance Nonoperative Watch & Wait (SNOWW) Rectal Cancer Trial.
The SNOWW trial evaluates a nonoperative watch-and-wait approach for rectal cancer, and the trial is currently not yet recruiting. This upda…