Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Quality of Life After Transanal Total Mesorectal Excision Compared to Traditional Total Mesorectal Excision
Completed clinical trial comparing transanal total mesorectal excision to traditional total mesorectal excision, with reported quality of li…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer [Phase 3]
Phase 3 trial comparing 2 vs 4 cycles of neoadjuvant CAPOX for low/intermediate risk II/III rectal cancer; current status is active but not …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) [NA]
A Washington University School of Medicine trial (WU-PE-CGS) is currently recruiting participants for cholangiocarcinoma, multiple myeloma, …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer [Phase 2]
Phase 2 trial evaluating short-course radiotherapy followed by CAPOX and immunotherapy with camrelizumab plus either bevacizumab or cetuxima…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
The trial sponsored by Amsterdam UMC (VUmc site) is currently recruiting to evaluate adaptive anastomosis techniques for anterior resection …
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients. [NA]
Pilot clinical trial evaluating psyllium husk for bowel dysfunction after low rectal resection in rectal cancer patients, focusing on Low An…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Improving Diagnosis and Treatment for Patients With Rectal Cancer [NA]
This clinical trial update indicates that Imperial College London is conducting a study aimed at improving diagnosis and treatment for recta…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: AI-Based Prediction of Pathological Response in Rectal Cancer Patients Receiving Total Neoadjuvant Therapy
A completed clinical trial evaluating AI-based prediction of pathological response in locally advanced rectal cancer patients receiving tota…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study [NA]
A pivotal colorectal cancer device trial (SAFE-2) evaluating the SafeHeal Colovac Colorectal Anastomosis Protection Device was terminated; r…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance [Phase 3]
Phase 3 clinical trial investigating intensified follow-up and surveillance after rectal cancer surgery to improve functional outcomes and q…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating nonoperative management after short-course radiotherapy followed by consolidation chemotherapy in locall…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: A Safety Study Adding Niraparib and Dostarlimab to Radiation Therapy for Rectal Cancers [Phase 1, Phase 2]
This clinical trial update notes termination of a safety study evaluating niraparib and dostarlimab in combination with radiation therapy fo…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) [Phase 2]
Phase 2 clinical trial assessing prophylactic mesalamine to prevent colitis after treatment with ipilimumab and nivolumab in patients with a…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Can Neoadjuvant Chemoradiotherapy be Ommited in Mid-rectal Cancer
A clinical trial investigating whether neoadjuvant chemoradiotherapy can be omitted for patients with mid-rectal cancer (rectal cancer stage…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection Syndrome [NA]
A clinical trial update describes a knowledge-enhanced digital intervention intended to prevent Low Anterior Resection Syndrome in patients …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer [Phase 3]
A Phase 3 study evaluating node-sparing short-course radiation combined with CAPOX and tislelizumab for MSS rectal cancer. The trial is curr…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial is investigating immunotherapy in combination with neoadjuvant chemoradiotherapy for locally advanced rectal cancer…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery [Phase 2]
Phase 2 clinical trial evaluating FOLFOX with Botensilimab and Balstilimab for localized rectal cancer before surgery is currently recruitin…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial [Phase 3]
A Phase III randomized trial (Neo-REACT) evaluating neoadjuvant radiotherapy with capecitabine versus TAS-102 for rectal adenocarcinoma; the…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Walking and Sitting Difficulties After Rectal Cancer Surgery [NA]
This clinical trial update shows a study examining walking and sitting difficulties after rectal cancer surgery is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: PET/MRI in Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating PET/MRI imaging in rectal cancer is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT) [Phase 2]
A Phase 2 trial (IT-TNT) is evaluating the combination of Iparomlimab and Tuvonralimab with total neoadjuvant therapy for locally advanced r…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating CEA Positive Rectal Cancer [Phase 1]
A Phase 1 clinical trial update describing an early-stage therapeutic biological product mix for CEA-positive rectal cancer.
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CLINICAL_TRIALS other · 2025-06-17Clinical Trial Update: Local Recurrence Due to Rectal Cancer in Sweden
A clinical trial in Sweden studying rectal cancer is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Neoadjuvant Therapy （NALIRIFOX） for Locally Advanced Colon and Upper Rectal Cancer [Phase 4]
Phase 4 clinical trial update evaluating neoadjuvant therapy with NALIRIFOX (liposomal irinotecan with fluorouracil/leucovorin) for locally …