Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study [Phase 3]
Phase 3 PALACE trial investigates long-course radiotherapy plus chemotherapy with or without immunotherapy for locally advanced rectal cance…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Efficacy of Neoadjuvant Folfirinox Regimen in Patients With Resectable Locally Advanced Rectal Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant FOLFIRINOX for resectable locally advanced rectal cancer has completed, reporting efficacy results.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer [NA]
Clinical trial update describing a study of organ preservation first strategy and an intentional watch-and-wait approach for MRI-defined low…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Non-Operative Management and Early Response Assessment in Rectal Cancer [NA]
An update on a clinical trial evaluating non-operative management and early response assessment in lower rectal adenocarcinoma; the study is…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29 [Phase 2]
Phase 2 clinical trial evaluating short-course radiotherapy followed by consolidation chemotherapy for locally advanced rectal cancer; curre…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN) [Phase 2]
Phase 2 trial in rectal cancer evaluating neoadjuvant radiotherapy followed by atezolizumab and bevacizumab. The study is currently active b…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Contact Radiotherapy for Rectal Cancer [NA]
This entry notes that a trial evaluating contact radiotherapy for rectal cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: A Prospective Single Arm Study of Intraoperative Radiotherapy for Locally Advanced or Recurrent Rectal Cancer [Phase 2]
A completed Phase 2 prospective single-arm trial evaluating intraoperative radiotherapy for locally advanced or recurrent rectal cancer.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer [NA]
A clinical trial evaluating whether pathologic analysis after neoadjuvant therapy can improve selection of patients for surgery in locally a…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: CRC Detection Reliable Assessment With Blood
A New Day Diagnostics trial is evaluating a blood-based method for detecting colorectal cancer and colorectal adenomas; the study is current…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating tumor local excision with postoperative adjuvant chemoradiotherapy for early-stage low/ultra-low rectal ca…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer [NA]
A completed clinical trial evaluating the da Vinci Linear Cutting Stapler SureForm in robotic anus-preserving surgery for rectal cancer has …
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Organ Preservation in Rectal AdenoCa Using Hypofractionated Pelvic RT(Hypo-OPRA) [Phase 2]
A Phase 2 study evaluating organ preservation in rectal cancer using hypofractionated pelvic radiotherapy; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: DESI - Düsseldorfer ESD Study
An ongoing clinical trial (DESI Düsseldorfer ESD study) is currently enrolling by invitation for patients with esophageal, gastric, duodenal…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer [NA]
ClinicalTrials.gov entry for a study evaluating selective defunctioning stoma in low anterior resection for rectal cancer; currently recruit…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Effect of Preserving the Left Colic Artery on Proximal Bowel Perfusion [NA]
A clinical trial evaluating whether preserving the left colic artery improves proximal bowel perfusion during rectal cancer surgery.
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CLINICAL_TRIALS withdrawal · 2025-05-21Clinical Trial Update: Neoadjuvant Chemoradiotherapy Plus Sintilimab for MSS, Locally Advanced Rectal Cancer- [Phase 2]
A Phase 2 trial evaluating neoadjuvant chemoradiotherapy plus sintilimab for microsatellite-stable locally advanced rectal cancer has been w…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer [NA]
This clinical trial entry outlines an informational and supportive care intervention for patients with locally advanced rectal cancer. The s…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Bovine Reinforcement in Stomach, Colorectal and Lung Operation [Phase 3]
Ongoing Phase 3 clinical trial sponsored by Shanghai Cingularbio evaluating bovine reinforcement in surgical procedures for rectal and lung …
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Patients With Rectal Cancer: a "Wait-and-see" Approach [NA]
A clinical trial at McGill University Health Centre is evaluating a wait-and-see approach for rectal cancer and is currently recruiting part…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial [NA]
A feasibility trial evaluating intraoperative electron radiotherapy for rectal cancer. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: SCRT + mFOLFOX6 + PD-1 Antibody + Targeted Therapy for HIgh-Risk pMMR/MSS Rectal Cancer [Phase 2]
Phase 2 trial evaluating SCRT + mFOLFOX6 + PD-1 inhibitor + targeted therapy for high-risk microsatellite-stable rectal cancer; currently re…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Adaptive Symptom Self-Management Immunotherapy Study [NA]
This clinical trial update from the University of Arizona describes an ongoing adaptive symptom self-management immunotherapy study that is …
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Study Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography to Detect Hypoxia in Locally Advanced (T3-T4 and./or N1)Primary Rectal Cancer Patients [NA]
A completed clinical trial evaluated Fluorine-18-labeled fluoro-misonidazole PET imaging to detect tumor hypoxia in locally advanced rectal …
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: Robotic Versus Laparoscopic Surgery for Middle and Low Rectal Cancer: a Target Trial Emulation
This update describes a target trial emulation comparing robotic and laparoscopic surgery for middle and low rectal cancer, and the study is…