Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I) [Phase 2]
A Phase 2 trial (Neo-Field I) is investigating involved-field radiotherapy with TNT combined with a PD-1 inhibitor for pMMR locally advanced…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Toripalimab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement [Phase 1]
Phase 1 clinical trial evaluating a neoadjuvant regimen combining radiotherapy with toripalimab, liposomal irinotecan, and capecitabine for …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: The Effect of Multimodal Treatment of Rectal Cancer on Circulating Tumor Cells: A Prospective, Observational Study
Prospective observational study to evaluate the effect of multimodal treatment on circulating tumor cells in rectal cancer. The study is cur…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Latitude - Lateral Lymph Node Attitude Study [NA]
This is a clinical trial update for the Latitude - Lateral Lymph Node Attitude Study in malignant rectal cancer, currently not yet recruitin…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II) [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating node-sparing short-course radiotherapy with sequential chemotherapy and a PD-1 inhibitor for mid/low p…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001 [Phase 2]
Phase 2 clinical trial evaluating short and long course radiation therapy with or without BMX-001 for rectal cancer; currently actively recr…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Immunotherapy in Patients With Early dMMR Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating immunotherapy for patients with early dMMR rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: ADAR1 Expression Level in Rectal Cancer
A recruiting clinical trial at Necmettin Erbakan University is investigating ADAR1 expression levels in rectal cancer.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Study On The Prediction of Neoadjuvant Efficacy For Rectal Cancer Based On MR Cytometry Imaging and Deep-radiomics
Clinical trial evaluating whether MR cytometry imaging and deep radiomics can predict neoadjuvant treatment efficacy in rectal cancer. The s…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Efficacy and Safety of Trastuzumab Biosimilars and Pertuzumab Biosimilars Combined With Chemotherapy for Neoadjuvant Treatment of Patients With Locally Advanced HER2-positive Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating trastuzumab biosimilars and pertuzumab biosimilars with chemotherapy as neoadjuvant therapy for locally ad…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Impact Of Metformin In Rectal Cancer Patients [Phase 2, Phase 3]
This update reports the completion of Phase 2 and Phase 3 trials evaluating metformin in rectal cancer patients.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)
A trial update for the CROSS study investigating low stable pressure pneumoperitoneum in colorectal surgery is currently recruiting patients…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Endorectal Brachytherapy for Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating endorectal brachytherapy for locally advanced rectal cancer has been suspended.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients [Phase 2]
A Phase 2 trial evaluating total neoadjuvant sandwich treatment via short-course radiotherapy for stage II/III rectal cancer. The study is c…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: A Prospective Feasibility Study Evaluating Extracellular Vesicles Obtained by Liquid Biopsy for Neoadjuvant Treatment Response Assessment in Rectal Cancer
A prospective feasibility study evaluating extracellular vesicles from liquid biopsy to assess neoadjuvant treatment response in rectal canc…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Perioperative Treatment With TAS-102 in Combination With Oxaliplatin for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 study evaluating perioperative TAS-102 in combination with oxaliplatin for locally advanced rectal cancer, focusing on event-free su…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Transanal Irrigation for the Management of LARS [NA]
This document reports an active-not-recruiting clinical trial at Jewish General Hospital evaluating transanal irrigation for managing Low An…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer [NA]
This clinical trial update indicates recruitment is ongoing for the ROBIN Molecular Characterization Trial of Standard Short Course Radiothe…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: DETECT: Target Volume for Rectal Endoluminal Radiation Boosting
This clinical trial entry describes DETECT, a study evaluating target volume for rectal endoluminal radiation boosting in rectal cancer, cur…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Irinotecan Liposomes in Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer [Phase 3]
A Phase 3 trial evaluating irinotecan liposome-based total neoadjuvant therapy for locally advanced rectal cancer, sponsored by Zhejiang Can…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. [Phase 2]
Phase 2 clinical trial evaluating total neoadjuvant therapy with or without tislelizumab for locally advanced rectal cancer; currently recru…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer [NA]
A clinical trial investigating MR-guided online adaptive radiotherapy for locally advanced rectal cancer. The study is currently not recruit…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit) [NA]
A UCSF-sponsored clinical trial called 'Tools To Be Fit' aims to improve nutrition and physical activity among cancer survivors and is curre…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial [Phase 1]
The DINOMITE Phase 1 trial is evaluating papaverine in combination with radiation therapy for locally advanced rectal cancer and is currentl…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Planed Organ Preservation for Low Rectal Cancer After Neoadjuvant Chemotherapy (OPLAR) [Phase 3]
A Phase 3 clinical trial (OPLAR) evaluating organ preservation for low rectal cancer after neoadjuvant chemotherapy; currently recruiting at…