Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating nonoperative management after short-course radiotherapy followed by consolidation chemotherapy in locall…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) [Phase 2]
Phase 2 clinical trial assessing prophylactic mesalamine to prevent colitis after treatment with ipilimumab and nivolumab in patients with a…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Can Neoadjuvant Chemoradiotherapy be Ommited in Mid-rectal Cancer
A clinical trial investigating whether neoadjuvant chemoradiotherapy can be omitted for patients with mid-rectal cancer (rectal cancer stage…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection Syndrome [NA]
A clinical trial update describes a knowledge-enhanced digital intervention intended to prevent Low Anterior Resection Syndrome in patients …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer [Phase 3]
A Phase 3 study evaluating node-sparing short-course radiation combined with CAPOX and tislelizumab for MSS rectal cancer. The trial is curr…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial is investigating immunotherapy in combination with neoadjuvant chemoradiotherapy for locally advanced rectal cancer…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery [Phase 2]
Phase 2 clinical trial evaluating FOLFOX with Botensilimab and Balstilimab for localized rectal cancer before surgery is currently recruitin…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial [Phase 3]
A Phase III randomized trial (Neo-REACT) evaluating neoadjuvant radiotherapy with capecitabine versus TAS-102 for rectal adenocarcinoma; the…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Walking and Sitting Difficulties After Rectal Cancer Surgery [NA]
This clinical trial update shows a study examining walking and sitting difficulties after rectal cancer surgery is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: PET/MRI in Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating PET/MRI imaging in rectal cancer is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT) [Phase 2]
A Phase 2 trial (IT-TNT) is evaluating the combination of Iparomlimab and Tuvonralimab with total neoadjuvant therapy for locally advanced r…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating CEA Positive Rectal Cancer [Phase 1]
A Phase 1 clinical trial update describing an early-stage therapeutic biological product mix for CEA-positive rectal cancer.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Neoadjuvant Therapy (NALIRIFOX) for Locally Advanced Colon and Upper Rectal Cancer [Phase 4]
Phase 4 clinical trial update evaluating neoadjuvant therapy with NALIRIFOX (liposomal irinotecan with fluorouracil/leucovorin) for locally …
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study [Phase 3]
Phase 3 PALACE trial investigates long-course radiotherapy plus chemotherapy with or without immunotherapy for locally advanced rectal cance…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer [NA]
Clinical trial update describing a study of organ preservation first strategy and an intentional watch-and-wait approach for MRI-defined low…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29 [Phase 2]
Phase 2 clinical trial evaluating short-course radiotherapy followed by consolidation chemotherapy for locally advanced rectal cancer; curre…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Contact Radiotherapy for Rectal Cancer [NA]
This entry notes that a trial evaluating contact radiotherapy for rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer [NA]
A clinical trial evaluating whether pathologic analysis after neoadjuvant therapy can improve selection of patients for surgery in locally a…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: CRC Detection Reliable Assessment With Blood
A New Day Diagnostics trial is evaluating a blood-based method for detecting colorectal cancer and colorectal adenomas; the study is current…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating tumor local excision with postoperative adjuvant chemoradiotherapy for early-stage low/ultra-low rectal ca…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Organ Preservation in Rectal AdenoCa Using Hypofractionated Pelvic RT(Hypo-OPRA) [Phase 2]
A Phase 2 study evaluating organ preservation in rectal cancer using hypofractionated pelvic radiotherapy; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: DESI - Düsseldorfer ESD Study
An ongoing clinical trial (DESI Düsseldorfer ESD study) is currently enrolling by invitation for patients with esophageal, gastric, duodenal…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer [NA]
ClinicalTrials.gov entry for a study evaluating selective defunctioning stoma in low anterior resection for rectal cancer; currently recruit…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Effect of Preserving the Left Colic Artery on Proximal Bowel Perfusion [NA]
A clinical trial evaluating whether preserving the left colic artery improves proximal bowel perfusion during rectal cancer surgery.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer [NA]
This clinical trial entry outlines an informational and supportive care intervention for patients with locally advanced rectal cancer. The s…