Catalyst Wire Dossier Catalyst Wire Dossier
CLINICAL_TRIALS research · 2025-06-18

Clinical Trial Update: Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT) [Phase 2]

View source ↗

Summary

A Phase 2 trial (IT-TNT) is evaluating the combination of Iparomlimab and Tuvonralimab with total neoadjuvant therapy for locally advanced rectal cancer that is…

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

Drugs mentioned

  • Tuvonralimab (tuvonralimab)
  • iparomlimab

Snippet

Sponsor: Shandong Cancer Hospital and Institute | Conditions: Rectal Malignant Neoplasms | Phase 2 | Status: RECRUITING