Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2026-03-06Clinical Trial Update: Exercise for Improving Radiotherapy Efficacy in Rectal Cancer [NA]
The clinical trial evaluating exercise to improve radiotherapy efficacy in locally advanced rectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2026-02-25Clinical Trial Update: A Trial of Regorafenib Plus Lorigerlimab in Patients With Locally Recurrent or Regrowing pMMR/MSS Localized Rectal Cancer [Phase 2]
ClinicalTrials.gov entry notes that a Phase 2 trial of regorafenib plus lorigerlimab for locally recurrent or regrowing pMMR/MSS localized r…
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CLINICAL_TRIALS withdrawal · 2025-08-28Clinical Trial Update: Effect of ICCAUT Strategy on Postoperative Urinary Retention After Radical Rectal Cancer Surgery (ICCAUT-2) [NA]
The ICCAUT-2 trial examining a strategy to prevent postoperative urinary retention after radical rectal cancer surgery has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-05-21Clinical Trial Update: Neoadjuvant Chemoradiotherapy Plus Sintilimab for MSS, Locally Advanced Rectal Cancer- [Phase 2]
A Phase 2 trial evaluating neoadjuvant chemoradiotherapy plus sintilimab for microsatellite-stable locally advanced rectal cancer has been w…
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CLINICAL_TRIALS withdrawal · 2024-11-21Clinical Trial Update: Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating Botensilimab and Balstilimab with or without Regorafenib for microsatellite-stable advanced or metastati…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Tucatinib Combined with Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study [Phase 2]
A Phase 2 trial evaluating tucatinib in combination with trastuzumab and TAS-102 for HER2-positive metastatic colorectal cancer in molecular…
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CLINICAL_TRIALS withdrawal · 2024-06-13Clinical Trial Update: GI Organ Tracking Via Balloon Applicators [NA]
A clinical trial evaluating GI organ tracking via balloon applicators sponsored by Washington University School of Medicine has been withdra…
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CLINICAL_TRIALS withdrawal · 2024-04-29Clinical Trial Update: Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME) [Phase 2]
A Phase 2 trial RX-CROME evaluating regorafenib with XmAb20717 for high-risk colorectal cancer patients with radiographic occult molecular r…
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CLINICAL_TRIALS withdrawal · 2018-03-22Clinical Trial Update: Mechanistic Prehabilitation [NA]
A mechanistic prehabilitation trial (NCT01919541) involving colon and rectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-08-31Clinical Trial Update: Closure of Protective Ileostomy 2 vs. 12 Weeks After TME [NA]
The clinical trial NCT02609451 evaluating two versus twelve week timing for protective ileostomy closure after total mesorectal excision in …
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CLINICAL_TRIALS withdrawal · 2017-01-25Clinical Trial Update: Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer [Phase 2]
Phase II study of Zaltrap (aflibercept) with chemotherapy for advanced resectable colorectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-01-20Clinical Trial Update: Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer [Phase 2]
A Phase 2 trial evaluating chemoradiation with pembrolizumab for rectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-10-12Clinical Trial Update: Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment [Phase 2]
The document notes that the Phase 2 trial of regorafenib to reduce recurrence in non-metastatic rectal cancer after curative treatment has b…
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CLINICAL_TRIALS withdrawal · 2016-07-15Clinical Trial Update: Feasibility Study to Develop Sentinel Lymph Node Mapping in Rectal Cancer Patients [NA]
A feasibility study on sentinel lymph node mapping in rectal cancer patients has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-05-20Clinical Trial Update: Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer [Phase 1, Phase 2]
This document reports the withdrawal of a Phase 1/2 trial evaluating BGJ398 (infigratinib), an FGFR kinase inhibitor, in combination with ch…
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CLINICAL_TRIALS withdrawal · 2015-05-06Clinical Trial Update: Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating Ziv-Aflibercept with fluorouracil and leucovorin for Stage IV colorectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-03-04Clinical Trial Update: Hydralazine as a Demethylating Agent in Rectal Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating hydralazine as a demethylating agent for rectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2014-12-18Clinical Trial Update: Phase II Trial of Preoperative High-dose-rate Endorectal Brachytherapy and FOLFOX Chemotherapy for Rectal Cancer [Phase 2]
A Phase II trial of preoperative high-dose-rate endorectal brachytherapy with FOLFOX for rectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2014-11-14Clinical Trial Update: Diverting Loop Ileostomy: With or Without Rod [NA]
Clinical trial NCT00959738 evaluating diverting loop ileostomy with or without a rod has been terminated.
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CLINICAL_TRIALS withdrawal · 2014-01-17Clinical Trial Update: Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer [EARLY_Phase 1]
An early-phase 1 trial evaluating cholecalciferol (25-[OH]-Vitamin D) for colorectal cancer was withdrawn and did not proceed.
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CLINICAL_TRIALS withdrawal · 2013-04-16Clinical Trial Update: Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing Chemotherapy and Radiation Therapy for Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery [Phase 1]
A Phase 1 trial studying biomarkers in tumor tissue and blood from stage II/III rectal cancer patients undergoing chemoradiation and planned…
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CLINICAL_TRIALS withdrawal · 2012-06-07Clinical Trial Update: S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum [Phase 2]
A phase 2 SWOG trial evaluating induction chemotherapy followed by chemoradiation for locally advanced rectal adenocarcinoma has been withdr…
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CLINICAL_TRIALS withdrawal · 2012-05-28Clinical Trial Update: Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers
A clinical trial on collection of biospecimens and clinical information from patients with gastrointestinal and gynecologic cancers was with…
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CLINICAL_TRIALS withdrawal · 2012-04-17Clinical Trial Update: Laparoscopic Surgery or Robotic-Assisted Laparoscopic Surgery in Treating Patients With Rectal Cancer That Can Be Removed By Surgery [NA]
A clinical trial comparing laparoscopic surgery with robotic-assisted laparoscopic surgery for rectal cancer has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-03-22Clinical Trial Update: Proton Therapy With Capecitabine for Rectal Cancer [Phase 1, Phase 2]
The trial evaluating capecitabine with proton therapy for rectal cancer has been withdrawn (Phase 1/Phase 2).