Pulp Necrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Efficacy of Lasers in Root Canal Treatment, Part II: Postoperative Pain [Phase 2]
A Phase 2 clinical trial evaluating the efficacy of lasers in reducing postoperative pain after root canal treatment has completed. The stud…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Diagnostic Accuracy of Cold, Heat, and Electric Pulp Tests
A completed clinical trial assessing the diagnostic accuracy of cold, heat, and electric pulp tests for dental pulp status.
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Obturation Quality in Primary Molars [NA]
Cairo University completed a clinical trial assessing obturation quality in necrotic primary molars.
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Antibacterial Effect of Two Different Intracanal Medicaments and Their Effect on Post-operative Pain [Phase 4]
Phase 4 clinical trial at Ain Shams University evaluating the antibacterial effects of two intracanal medicaments and their impact on postop…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: CGF-Enhanced Autologous Pulp Transplantation in Mature Necrotic Teeth [NA]
Completed clinical trial evaluating CGF-Enhanced Autologous Pulp Transplantation in mature necrotic teeth.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: PRF and CGF Scaffolds With EDTA in Regeneration [NA]
This entry reports a completed clinical trial evaluating PRF and CGF scaffolds with EDTA for regenerative endodontics in immature permanent …
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Pulp Transplantation in Necrotic Mature Teeth With Periapical Radiolucency [NA]
This entry notes the completion of a clinical trial evaluating pulp transplantation for regenerating dental pulp in necrotic mature teeth wi…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Three Techniques in Bioceramic Apexification for Necrotic Immature Incisors [NA]
Clinical trial completion update on three bioceramic apexification techniques for necrotic immature incisors, sponsored by Damascus Universi…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain [NA]
A dental clinical trial is recruiting to evaluate how the number of rotary files used affects MB2 canal negotiation and postoperative pain.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Application of Advanced Platelet-Rich Fibrin Plus (A-PRF+) in Revascularisation of Necrotic Immature Permanent Teeth [NA]
A clinical trials update reports the completion of a study evaluating Advanced Platelet-Rich Fibrin Plus (A-PRF+) for revascularization of n…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Non-instrumentation Root Canal Treatment of Primary Molars [NA]
A completed clinical trial from the University of Sao Paulo evaluating non-instrumentation root canal treatment in primary molars for dental…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods [NA]
Clinical trial update on antibacterial efficacy of root canal irrigation methods; currently enrolling by invitation for conditions including…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Dexamethasone Treatment for Patients Undergoing Endodontics [Phase 4]
Phase 4 trial update announcing the completion of a dexamethasone treatment study in patients undergoing endodontic therapy for pulp necrosi…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial [NA]
This completed randomized controlled trial compares periapical bleeding versus platelet-rich fibrin (PRF) techniques in regenerative endodon…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Success of Lesion Sterilization and Tissue Repair Therapy [Phase 4]
Phase 4 clinical trial completed evaluating lesion sterilization and tissue repair therapy (LSTR) in primary teeth with pulp necrosis or irr…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Treatments of the Necrosed Immature Teeth (REV) [Phase 2]
Phase 2 trial evaluating treatments for necrosed immature teeth reported clinical and radiographic success at 24 months, but the study was t…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Postoperative Pain and Periapical Tissue Healing [NA]
A completed clinical trial update focusing on postoperative pain and healing of periapical tissue in cases of necrotic mandibular molars.
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth [NA]
A completed clinical trial evaluating Epigallocatechin-3-Gallate as a root canal irrigant to reduce post-operative pain and bacterial load i…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Evaluation of Platelet-rich Fibrin for Revascularization of Immature Permanent Teeth Versus Standard Apexification [Phase 3]
Phase 3 clinical trial evaluating platelet-rich fibrin for revascularization of necrotic immature permanent teeth with open apices, compared…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars [NA]
A completed clinical trial evaluated bacterial reduction when using rotary versus manual filing systems with different irrigants in primary …
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation. [NA]
Completed clinical trial evaluating histopathological effects of laser ablation on the periodontal ligament in pulp necrosis cases; results …
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: The Efficacy of Laser in Root Canal Disinfection [Phase 2]
Phase 2 trial evaluating the efficacy of laser disinfection in root canal treatment has completed.
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CLINICAL_TRIALS trial_result · 2020-11-04Clinical Trial Update: Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth [Phase 2]
Phase 2 clinical trial evaluating combined blood clot and platelet-rich fibrin scaffolds for regeneration in necrotic immature permanent tee…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluated using an apical matrix with apexification to improve apical healing in necrotic immature teet…
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CLINICAL_TRIALS trial_result · 2019-01-17Clinical Trial Update: Magnetic Resonance Imaging (MRI) of Pulp Regeneration [Phase 2]
A Phase 2 clinical trial evaluating MRI imaging for pulp regeneration in teeth with pulp necrosis and periapical lesions has completed.