Pulp Necrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques [NA]
A clinical trial comparing lateral condensation and warm vertical obturation techniques for root canal treatment, assessing postoperative pa…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Lesion Sterilization and Tissue Repair Antibiotic Paste Versus Zinc Oxide and Eugenol Pulpectomy for Treatment of Primary Molars With Pulp Necrosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing Lesion Sterilization and Tissue Repair Antibiotic Paste with Zinc Oxide and Eugenol pulpectomy for trea…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Efficacy of Lasers in Root Canal Treatment, Part II: Postoperative Pain [Phase 2]
A Phase 2 clinical trial evaluating the efficacy of lasers in reducing postoperative pain after root canal treatment has completed. The stud…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France
A France-based clinical trial evaluating professional practices among dental surgeons for treating non-vital primary teeth, including cases …
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Diagnostic Accuracy of Cold, Heat, and Electric Pulp Tests
A completed clinical trial assessing the diagnostic accuracy of cold, heat, and electric pulp tests for dental pulp status.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Antibacterial Effect and Postoperative Pain After Triton Irrigation Protocol in Necrotic Mandibular Molar [NA]
A clinical trial evaluating the antibacterial effect and postoperative pain of a Triton irrigation protocol in teeth with pulp necrosis; the…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Antibacterial Effect and Post-operative Pain Following Various Techniques of Intracanal Heating of NaOCL [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the antibacterial effect and postoperative pain of different intracanal heating techniques for sodi…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Interleukin 8 and10 Levels Changes in Teeth With Necrotic Pulp and Apical Periodontitis [NA]
A completed clinical trial evaluating changes in interleukin-8 and interleukin-10 levels in teeth with necrotic pulp and apical periodontiti…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Obturation Quality in Primary Molars [NA]
Cairo University completed a clinical trial assessing obturation quality in necrotic primary molars.
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Antibacterial Effect of Two Different Intracanal Medicaments and Their Effect on Post-operative Pain [Phase 4]
Phase 4 clinical trial at Ain Shams University evaluating the antibacterial effects of two intracanal medicaments and their impact on postop…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids [NA]
Clinical trial update indicates ongoing research on regenerative root canal treatment for immature teeth with open apex using omega-3 fatty …
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Evaluation of Pain Relief and Bacterial Reduction After Using Calcium Hydroxide With Mesoporous Silica Nanoparticles as an Intracanal Medicament in Necrotic Mandibular Molars: A Randomized Controlled Clinical Trial [NA]
A randomized controlled trial is evaluating pain relief and bacterial reduction when using calcium hydroxide combined with mesoporous silica…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: CGF-Enhanced Autologous Pulp Transplantation in Mature Necrotic Teeth [NA]
Completed clinical trial evaluating CGF-Enhanced Autologous Pulp Transplantation in mature necrotic teeth.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit [NA]
A randomized clinical trial compares step-down versus step-back techniques for cleaning and shaping during root canal treatment to determine…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: PRF and CGF Scaffolds With EDTA in Regeneration [NA]
This entry reports a completed clinical trial evaluating PRF and CGF scaffolds with EDTA for regenerative endodontics in immature permanent …
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Pulp Transplantation in Necrotic Mature Teeth With Periapical Radiolucency [NA]
This entry notes the completion of a clinical trial evaluating pulp transplantation for regenerating dental pulp in necrotic mature teeth wi…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Comparison Between Emdogain and Amniotic Membrane as a Scaffold in Endodontic Regeneration of Immature Anterior Teeth [NA]
This clinical trial compares enamel matrix derivative (Emdogain) with an amniotic membrane scaffold for regenerative treatment of non-vital …
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Revascularization of Young Immature Permenant Teeth Using Different Types of Intra Canal Medication [NA]
This clinical trial update describes evaluating different intra-canal medications for revascularization of young, immature permanent teeth i…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp [NA]
This clinical trial entry registers a study comparing pulpotomy versus pulpectomy in primary molars with irreversible pulpitis or pulp necro…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair [NA]
Ain Shams University-led clinical trial evaluating different medicaments for managing necrotic primary molars using lesion sterilization and…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth [NA]
This clinical trial update concerns using platelet-rich fibrin in regenerative endodontic treatment for mature permanent teeth, sponsored by…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars [NA]
A clinical trial evaluating bacterial load reduction in mandibular necrotic molars using GentleWave and EdgePro irrigation systems is curren…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Three Techniques in Bioceramic Apexification for Necrotic Immature Incisors [NA]
Clinical trial completion update on three bioceramic apexification techniques for necrotic immature incisors, sponsored by Damascus Universi…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Effect of Different NanoScaffolds on Pulp Regeneration in Non-Vital Immature Permanent Teeth (Randomized Clinical Trial) [NA]
This clinical trial from Tanta University tests various nano-scaffolds to promote pulp regeneration in necrotic immature permanent incisors;…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Effect of Bio-C Temp Versus Calcium Ydroxide as Intracanal Dressings on Postoperative Pain Intensity and Periapical MMP-9 Level in Patients With Necrotic Pulp [EARLY_Phase 1]
ClinicalTrials.gov notes an early Phase 1 study comparing Bio-C Temp with calcium hydroxide as intracanal dressings in patients with necroti…