Pulp Necrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Comparative Evaluation of the Degree of Pain and MMP-9 Expression Following Instrumentation of Necrotic Pulps With Apical Periodontitis in One or Two Visits [NA]
A clinical trial evaluating pain and MMP-9 expression after root canal instrumentation of necrotic pulps with apical periodontitis, comparin…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain [NA]
A dental clinical trial is recruiting to evaluate how the number of rotary files used affects MB2 canal negotiation and postoperative pain.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Regenerative Endodontic Treatment Using Sodium Hexametaphosphate (SHMP) For Necrotic Immature Permanent Anterior Teeth [Phase 1, Phase 2]
This Phase 1/2 clinical trial assesses regenerative endodontic treatment using sodium hexametaphosphate for necrotic immature permanent ante…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Application of Advanced Platelet-Rich Fibrin Plus (A-PRF+) in Revascularisation of Necrotic Immature Permanent Teeth [NA]
A clinical trials update reports the completion of a study evaluating Advanced Platelet-Rich Fibrin Plus (A-PRF+) for revascularization of n…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Non-instrumentation Root Canal Treatment of Primary Molars [NA]
A completed clinical trial from the University of Sao Paulo evaluating non-instrumentation root canal treatment in primary molars for dental…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods [NA]
Clinical trial update on antibacterial efficacy of root canal irrigation methods; currently enrolling by invitation for conditions including…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars [NA]
Clinical trial at Cairo University comparing Moringa Oleifera to Sodium Hypochlorite for root canal irrigation in nonvital primary molars is…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Evaluation of Moringa Oleifera Leaf Extract Versus Sodium Hypochlorite in Pulpectomy of Nonvital Primary Molars [NA]
A clinical trial comparing moringa oleifera leaf extract to sodium hypochlorite as irrigants in pulpectomy of nonvital primary molars; the s…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Maximum Occlusal Bite Force of Necrotic Permanent Teeth Treated by Regenerative Technique: Randomized Clinical Trial [NA]
A randomized clinical trial investigating the maximum occlusal bite force of necrotic permanent teeth treated with regenerative endodontic p…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Photodynamic Therapy in Root Canal Treatment of T2DM Patients: Microbiome Analysis Via Next-Gen Sequencing [NA]
A completed study evaluating photodynamic therapy as an adjunct to root canal treatment in patients with type 2 diabetes, including microbio…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Dexamethasone Treatment for Patients Undergoing Endodontics [Phase 4]
Phase 4 trial update announcing the completion of a dexamethasone treatment study in patients undergoing endodontic therapy for pulp necrosi…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial [NA]
This completed randomized controlled trial compares periapical bleeding versus platelet-rich fibrin (PRF) techniques in regenerative endodon…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Success of Lesion Sterilization and Tissue Repair Therapy [Phase 4]
Phase 4 clinical trial completed evaluating lesion sterilization and tissue repair therapy (LSTR) in primary teeth with pulp necrosis or irr…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Treatments of the Necrosed Immature Teeth (REV) [Phase 2]
Phase 2 trial evaluating treatments for necrosed immature teeth reported clinical and radiographic success at 24 months, but the study was t…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Postoperative Pain and Periapical Tissue Healing [NA]
A completed clinical trial update focusing on postoperative pain and healing of periapical tissue in cases of necrotic mandibular molars.
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth [NA]
A completed clinical trial evaluating Epigallocatechin-3-Gallate as a root canal irrigant to reduce post-operative pain and bacterial load i…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Clinical and Radiographic Evaluation of Zinc Oxide Modified 3Mixtatin Versus Zical in Root Canal Treatment of Necrotic Primary Molars. [NA]
This clinical trial update evaluates zinc oxide modified 3Mixtatin against Zical for root canal treatment of necrotic primary molars; no res…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Regenerative Ability of Immature Necrotic Permanent Teeth Using Different Scaffolds [NA]
An ongoing clinical trial from Ain Shams University is evaluating regenerative approaches for immature necrotic permanent teeth using differ…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Evaluation of Platelet-rich Fibrin for Revascularization of Immature Permanent Teeth Versus Standard Apexification [Phase 3]
Phase 3 clinical trial evaluating platelet-rich fibrin for revascularization of necrotic immature permanent teeth with open apices, compared…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Postoperative Pain After Conservative Root Canal Preparation [NA]
This update notes the completion of a clinical trial sponsored by Istanbul University studying postoperative pain after conservative root ca…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: The Present Study Was Conducted to Evaluate Bioceramic Root Repair Material Versus Bio MTA in Revascularization of Immature Young Permenant Teeth. [Phase 2]
This Phase 2 trial compares Bioceramic Root Repair Material with Bio MTA for revascularization in immature permanent teeth and is currently …
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth [NA]
A not-yet-recruiting clinical trial is evaluating integrated nano-technology for revascularization of immature necrotic teeth, sponsored by …
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. . [NA]
This clinical trial compares calcium hypochlorite versus sodium hypochlorite as root canal irrigants to impact postoperative pain and bacter…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars [NA]
A completed clinical trial evaluated bacterial reduction when using rotary versus manual filing systems with different irrigants in primary …
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation. [NA]
Completed clinical trial evaluating histopathological effects of laser ablation on the periodontal ligament in pulp necrosis cases; results …