Pulmonary Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-07-23Clinical Trial Update: Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT [Phase 2]
A Phase 2 clinical trial (LARIAT) evaluating Bardoxolone Methyl in patients with pulmonary hypertension has completed and results have been …
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE [Phase 2, Phase 3]
Phase 2/3 trial evaluating inhaled treprostinil for pulmonary hypertension associated with interstitial lung disease, including combined pul…
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial evaluating glutamine therapy for hemolysis-associated pulmonary hypertension in patients with sickle cell disease. St…
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CLINICAL_TRIALS trial_result · 2021-04-01Clinical Trial Update: Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation [Phase 2]
This update reports results from a Phase 2 study evaluating Macitentan for efficacy and safety in patients with pulmonary hypertension after…
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease [Phase 2]
Phase 2 trial evaluating tadalafil for pulmonary hypertension due to chronic lung disease (COPD) has completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-01Clinical Trial Update: Study to Assess the Longterm Safety of Sildenafil Citrate in Patients With Pulmonary Arterial Hypertension [Phase 3]
A Phase 3 study assessing long-term safety of sildenafil citrate in patients with pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Chronic Clinical Effect of Acetazolamide [Phase 2, Phase 3]
Clinical trial update for chronic clinical effect of Acetazolamide in hypertension and pulmonary conditions, completed Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Macitentan in Pulmonary Hypertension of Sickle Cell Disease [Phase 2]
Phase 2 trial of macitentan for pulmonary hypertension associated with sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2020-11-04Clinical Trial Update: Pharmacodynamic Effects of Riociguat in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 study evaluating pharmacodynamic effects of riociguat in pulmonary hypertension and heart failure with preserved ejection fraction (…
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan [Phase 4]
Phase 4 trial updating exercise-induced pulmonary hypertension in systemic sclerosis and treatment with ambrisentan.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery [Phase 3]
Phase 3 trial update for Remodulin in pediatric pulmonary hypertension with single-ventricle physiology after Fontan surgery has completed.
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CLINICAL_TRIALS trial_result · 2020-10-23Clinical Trial Update: THERAPY-HYBRID-BPA Trial [Phase 2]
Clinical trial update for THERAPY-HYBRID-BPA, a Phase 2 study sponsored by Okayama Medical Center.
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction [Phase 3]
Phase 3 trial of oral treprostinil in pulmonary hypertension due to heart failure with preserved ejection fraction was terminated; results p…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial Hypertension [Phase 2]
Phase 2 trial update for selexipag in schistosomiasis-associated pulmonary arterial hypertension is reported as ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Study of Ambrisentan in Participants With Pulmonary Hypertension [Phase 3]
Phase 3 clinical trial update for ambrisentan in participants with pulmonary hypertension; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants [Phase 1]
Phase 1 trial comparing relative bioavailability of marketed versus lower-dose ambrisentan in healthy adults; study completed with results p…
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CLINICAL_TRIALS trial_result · 2020-04-21Clinical Trial Update: ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1) [Phase 3]
Phase 3 trial ORal Iron supplementation with ferric maltol in pulmonary hypertension was terminated.
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Auto-PAP for Pulmonary Hypertension Treatment in Decompensated HF Patients With Sleep Apnea. [NA]
A completed clinical trial evaluating Auto-PAP therapy for pulmonary hypertension treatment in patients with decompensated heart failure and…
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: Upfront Combination Pulmonary Arterial Hypertension Therapy [Phase 4]
A Phase 4 clinical trial update on upfront combination therapy for pulmonary hypertension is reported, with the status currently UNKNOWN.
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CLINICAL_TRIALS trial_result · 2020-02-06Clinical Trial Update: Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing and Sleep [Phase 4]
Phase 4 clinical trial investigating the effect of oxygen on breathing and sleep in patients with precapillary pulmonary hypertension and in…
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CLINICAL_TRIALS trial_result · 2019-10-08Clinical Trial Update: Efficacy and Safety of Ambrisentan in Children 8-18yrs [Phase 2]
Phase 2 trial update on ambrisentan in children aged 8-18 assessing efficacy and safety; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Acute Effects of rhBNP in Patients With PH Associated With Acute Exacerbation of Chronic Pulmonary Disease [Phase 4]
Phase 4 clinical trial update on acute effects of recombinant human B-type natriuretic peptide (rhBNP) in patients with pulmonary hypertensi…
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CLINICAL_TRIALS trial_result · 2019-09-18Clinical Trial Update: Cell Proliferation in Pulmonary Hypertension. FDG-PET Comparison Between Patients and Healthy Subjects [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating FDG-PET based cell proliferation in pulmonary hypertension, comparing patients to healthy subjects; s…
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Simvastatin as a Treatment for Pulmonary Hypertension [Phase 1, Phase 2]
Clinical trial update investigating simvastatin for pulmonary hypertension across Phase 1 and Phase 2, with completed status and results pos…
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CLINICAL_TRIALS trial_result · 2019-08-13Clinical Trial Update: Acute Hemodynamic Effect of Acetazolamide in Pulmonary Hypertension [Phase 2, Phase 3]
Phase 2/3 clinical trial investigating the acute hemodynamic effects of acetazolamide in pulmonary hypertension has completed.