Pulmonary Hypertension
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023) [Phase 2]
An extension-study trial update for sotatercept in people with pulmonary hypertension, currently in Phase 2 and recruiting (MK-7962-023).
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Real World Observational Study of Sotatercept for Pulmonary Hypertension
Real-world observational study assessing sotatercept for patients with pulmonary hypertension, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Non-Invasive and Invasive Assessment of Heart Filling Pressure
A completed clinical trial evaluating non-invasive and invasive methods to assess heart filling pressure in patients with heart failure and …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension [NA]
A multi-site clinical trial evaluates the clinical impact of an AI-assisted referral approach for diagnosing pulmonary hypertension in patie…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension [Phase 1]
Phase 1 Mayo Clinic study evaluating a bridge-to-lung transplant approach using trans-septal ECMO to support patients with right heart failu…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes
A real-world registry study focusing on pediatric pulmonary hypertension to investigate its epidemiology and patient outcomes.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants [NA]
A clinical trial update indicates a study investigating oxygen saturation targeting in preterm infants with bronchopulmonary dysplasia and p…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study) [Phase 2]
Phase 2 clinical trial APEX is evaluating TX000045 for pulmonary hypertension secondary to heart failure with preserved ejection fraction an…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Reverse Remodeling of the Pulmonary Vasculature: a Longitudinal, Investigational Study of the Effects of Sotatercept.
This clinical trial update outlines an investigational longitudinal study to evaluate reverse remodeling of the pulmonary vasculature with S…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Portosystemic Shunt-associated Pulmonary Hypertension Multi-center Prospective Cohort Study
This entry describes a multi-center prospective cohort study on portosystemic shunt–associated pulmonary hypertension, which is currently no…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Development of Novel Physiological CMR Methods in Health and Disease [NA]
This clinical trial update describes development of novel physiological cardiovascular magnetic resonance (CMR) methods across health and di…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Trans-pulmonary Biomarkers in Pulmonary Hypertension
A Vanderbilt University-led clinical trial (NCT01961232) investigating trans-pulmonary biomarkers in pulmonary hypertension is currently act…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders
This entry describes a clinical trial to establish a biobank and registry for adult congenital heart disease and related disorders, sponsore…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease [Phase 2]
A Phase 2 clinical trial update for TX000045 in participants with pulmonary hypertension due to interstitial lung disease; recruitment has n…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease [NA]
Clinical trial update for a randomized study evaluating the Enhancor System, a pulmonary artery denervation device, in patients with combine…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Preliminary Human Trials of F230 Tablets [Phase 1]
Phase 1 preliminary human trials of F230 tablets are underway, with recruitment ongoing for pulmonary hypertension. The sponsor is Beijing C…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Validation of a Patient Knowledge Questionnaire for Pulmonary Hypertension [NA]
A clinical trial update on validating a Patient Knowledge Questionnaire for pulmonary hypertension is currently recruiting, sponsored by Uni…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT) [Phase 2, Phase 3]
This entry describes a randomized trial of sildenafil for pulmonary hypertension in patients with rheumatic valvular heart disease, spanning…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Prospective Evaluation of AI-ECG for SHD Detection
Imperial College London is conducting a prospective study to evaluate an AI-enabled ECG for detecting structural heart disease; the trial is…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Phosphodiesterase Type 5 Inhibitors in Patients With Group 2 Pulmonary Hypertension [NA]
A clinical trial update notes that a study evaluating phosphodiesterase type 5 inhibitors for Group 2 pulmonary hypertension is currently ac…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Electrical Impedance Tomography for Assessment of Pulmonary Hypertension [NA]
A University of Sao Paulo General Hospital study is evaluating electrical impedance tomography as a noninvasive tool to assess pulmonary hyp…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Pulmonary Hypertension in Left Heart Disease
Mayo Clinic is recruiting for a study addressing pulmonary hypertension in the context of left heart disease and related pulmonary vascular …
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Efficacy and Tolerance of Treatment With Bevacizumab for Severe Liver Involvement With High Cardiac Output in Hereditary Hemorrhagic Telangiectasia Within the French Hereditary Hemorrhagic Telangiectasia Network
A clinical trial update reports on the efficacy and tolerability of Bevacizumab for severe liver involvement with high cardiac output in her…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Deep-Learning-Enabled Electrocardiogram for Detecting Pulmonary Hypertension [NA]
This clinical trial is evaluating a deep-learning-enabled electrocardiogram for detecting pulmonary hypertension and is currently recruiting…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: 129 Xenon Imaging in Patients Treated With Sotatercept [Phase 2]
A Phase 2 clinical trial using Xenon imaging in patients treated with sotatercept for pulmonary hypertension is currently recruiting.