Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain [Phase 2]
Phase 2 clinical trial evaluating the Qutenza capsaicin patch to reduce pain at treprostinil (Remodulin) infusion sites in pulmonary hyperte…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies
The ClinicalTrials.gov update reports results comparing the incidence of respiratory tract adverse events in patients with pulmonary arteria…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH) [Phase 1]
A Phase 1 safety trial evaluating PLX-PAD cells for pulmonary arterial hypertension has been terminated.
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH. [Phase 4]
Phase 4 trial update characterizes left ventricular strain patterns in patients with mildly elevated pulmonary capillary wedge pressure and …
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CLINICAL_TRIALS trial_result · 2015-10-26Clinical Trial Update: Post Marketing Observational Study in Patients With Pulmonary Arterial Hypertension
This entry notes the completion of a post-marketing observational study in patients with pulmonary arterial hypertension sponsored by Eli Li…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin
A completed pharmacokinetics study evaluating how OATP1B1 and CYP2C9 genotypes influence bosentan exposure before and during co-administrati…
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3) [EARLY_Phase 1]
A Phase 1 study from the University of Edinburgh evaluated the roles of ETA and ETB receptors in the vasodilatory response to endothelin-3 i…
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CLINICAL_TRIALS trial_result · 2015-07-13Clinical Trial Update: Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH) [Phase 3]
Phase 3 extension study evaluating long-term safety, tolerability, and efficacy of imatinib in severe pulmonary arterial hypertension. The t…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan
A clinical trial update reported results on how CYP3A4 induction by St. John's Wort alters the steady-state pharmacokinetics of ambrisentan,…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan
A pharmacokinetic study assessed how induction of CYP3A4 by St. John's Wort alters the steady-state exposure of bosentan, informing potentia…
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CLINICAL_TRIALS trial_result · 2015-05-21Clinical Trial Update: Extension to QTI571A2301 to Evaluate the Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH) [Phase 3]
Extension of the Phase 3 QTI571A2301 trial evaluating imatinib for severe pulmonary arterial hypertension to assess long-term safety, tolera…
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Efficacy Study of Ambrisentan in Chinese Patients With Pulmonary Arterial Hypertension (PAH) [Phase 3]
Phase 3 efficacy study of ambrisentan in Chinese patients with pulmonary arterial hypertension has completed and posted results.
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension [Phase 4]
Phase 4 clinical trial update examining the effects of spironolactone on collagen metabolism in patients with pulmonary arterial hypertensio…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Impact of Inhaled Treprostinil Sodium on Ventilation Perfusion Matching
A terminated clinical trial evaluating inhaled treprostinil for ventilation-perfusion matching in pulmonary arterial hypertension and chroni…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) [Phase 3]
Phase 3 trial evaluating first-line ambrisentan and tadalafil combination therapy in pulmonary arterial hypertension has completed with resu…
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CLINICAL_TRIALS trial_result · 2015-04-23Clinical Trial Update: Ranolazine and Pulmonary Hypertension [Phase 3]
Phase 3 trial update reporting completed results for ranolazine in patients with angina and pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2015-03-27Clinical Trial Update: Assessmet of Patients With PAH Right Ventricular Volume [NA]
Completed clinical trial update from VentriPoint Diagnostics assessing right ventricular volume in patients with pulmonary arterial hyperten…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Phase III Randomized Study of UT-15 in Patients With Primary Pulmonary Hypertension [Phase 3]
Phase III randomized trial evaluating UT-15 in patients with pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: Safety and Efficacy of Imatinib Mesylate in Patients With Pulmonary Arterial Hypertension [Phase 2, Phase 3]
This update reports the results of a Phase 2/Phase 3 study evaluating the safety and efficacy of imatinib mesylate in patients with pulmonar…
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CLINICAL_TRIALS trial_result · 2015-03-20Clinical Trial Update: Coenzyme Q-10 and Pulmonary Arterial Hypertension [NA]
A completed clinical trial evaluating Coenzyme Q-10 for pulmonary arterial hypertension has posted its results.
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CLINICAL_TRIALS trial_result · 2015-02-02Clinical Trial Update: Observation of Patients With Primary Pulmonary Hypertension Receiving Prescribed Ventavis Inhalation Therapy Regarding Safety and Efficacy for up to 4 Years
This trial update presents long-term safety and efficacy observations for inhaled iloprost (Ventavis) in patients with primary pulmonary art…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH) [Phase 4]
Phase 4 trial comparing bosentan plus sildenafil versus sildenafil alone in pulmonary arterial hypertension; results have been posted.
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CLINICAL_TRIALS trial_result · 2015-01-13Clinical Trial Update: Epoprostenol for Injection (EFI/ACT-385781A) - Pulmonary Arterial Hypertension [Phase 3]
Phase 3 clinical trial update for epoprostenol for injection (EFI/ACT-385781A) in pulmonary arterial hypertension; the study completed and r…
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CLINICAL_TRIALS trial_result · 2014-12-29Clinical Trial Update: Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart Disease [NA]
Clinical trial evaluating iloprost for pulmonary hypertension in adults with congenital heart disease was terminated; results were posted in…
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Nitric Oxide, GeNO Nitrosyl Delivery System [Phase 2]
Phase 2 trial of the GeNO Nitrosyl Delivery System for pulmonary arterial hypertension has completed and results have been posted.