Clinical Trial Update: Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

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Summary

A pharmacokinetic study assessed how induction of CYP3A4 by St. John's Wort alters the steady-state exposure of bosentan, informing potential drug interaction r…

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Diseases / indications

• Pulmonary Arterial Hypertension

Drugs mentioned

• TRACLEER (bosentan)

Snippet

Sponsor: Gerd Mikus | Conditions: Drug Interactions | Status: COMPLETED | Results posted: 2015-06-02