Clinical Trial Update: Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin

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Summary

A completed pharmacokinetics study evaluating how OATP1B1 and CYP2C9 genotypes influence bosentan exposure before and during co-administration with clarithromyc…

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Diseases / indications

• Pulmonary Arterial Hypertension

Drugs mentioned

• Biaxin (clarithromycin)
• TRACLEER (bosentan)

Snippet

Sponsor: Gerd Mikus | Conditions: Drug Interactions | Status: COMPLETED | Results posted: 2015-08-04