Pruritus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis [Phase 2]
A Phase 2 study evaluating the efficacy and safety of oral difelikefalin (CR845) for moderate to severe pruritus in subjects with atopic der…
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section [Phase 2]
Phase 2 trial investigating the effect of granisetron on morphine-induced pruritus, completed.
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CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects [Phase 1, Phase 2]
A Phase 1/Phase 2 proof-of-concept trial evaluated topical acetaminophen for itch relief in healthy subjects; the study is completed and res…
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CLINICAL_TRIALS trial_result · 2021-03-01Clinical Trial Update: Adding Nalbuphine for Control of Intrathecal Morphine Pruritus [Phase 2]
Phase 2 clinical trial exploring nalbuphine to control intrathecal morphine–induced pruritus in postoperative patients.
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients? [Phase 4]
Phase 4 trial evaluating whether intravenous ondansetron reduces itch after intrathecal morphine in pediatric patients has been terminated; …
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CLINICAL_TRIALS trial_result · 2020-11-30Clinical Trial Update: Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch) [Phase 3]
Phase 3 long-term safety study of serlopitant for pruritus was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis [Phase 3]
Phase 3 trial investigating serlopitant for pruritus associated with prurigo nodularis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus [Phase 2, Phase 3]
Clinical trial update reporting results from Phase 2/3 studies of nalbuphine HCl extended-release tablets for uremic pruritus in hemodialysi…
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus [Phase 2, Phase 3]
Open-label extension study of nalbuphine ER in hemodialysis patients with uremic pruritus has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis [Phase 3]
Phase 3 trial evaluating serlopitant for pruritus associated with prurigo nodularis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration [Phase 4]
Phase 4 trial update examining recovery quality after intrathecal morphine administration with dexamethasone, ondansetron, or placebo; resul…
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CLINICAL_TRIALS trial_result · 2019-10-04Clinical Trial Update: Safety Study of Levocetirizine and Fexofenadine [Phase 4]
Phase 4 safety study investigating levocetirizine and fexofenadine in pruritus and chronic urticaria completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-07-02Clinical Trial Update: Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine [Phase 2]
Phase 2 trial investigating the antipruritic effect of a topical combination of ketamine, amitriptyline, and lidocaine for pruritus was term…
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CLINICAL_TRIALS trial_result · 2019-07-02Clinical Trial Update: Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients [Phase 2]
Phase 2 trial update for a neurokinin-1 receptor antagonist addressing itch in epidermolysis bullosa patients; results posted after completi…
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CLINICAL_TRIALS trial_result · 2019-06-12Clinical Trial Update: Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis [Phase 2]
Phase 2 clinical trial evaluating serlopitant for pruritus in plaque psoriasis has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene [Phase 2]
Phase 2 trial evaluating SNA-120 for pruritus and psoriasis in patients treated with calcipotriene, focusing on safety, tolerability, and ef…
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CLINICAL_TRIALS trial_result · 2018-09-11Clinical Trial Update: Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching [Phase 4]
A Phase 4 clinical trial evaluating a long-acting antihistamine for opioid-induced itching has been terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Evaluate the Efficacy and Safety of HL151 Versus Talion Tab. in Pruritus Cutaneus [Phase 3]
Phase 3 trial comparing HL151 to Talion Tab for pruritus completed.
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Gabapentin to Treat Itch in Patients With Liver Disease [Phase 3]
This update reports the completion of a Phase 3 trial evaluating gabapentin to treat itch in patients with liver disease.
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Itch Relieving Effect of Botox: a Study in Healthy Subjects [Phase 1, Phase 2]
A phase 1/2 clinical trial examines whether Botox (onabotulinumtoxinA) relieves itch in healthy subjects, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405 [Phase 1]
Phase 1 study to assess mass balance recovery, metabolite profile, and metabolite identification of [14C]-SK-1405. The trial status is compl…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch [Phase 1, Phase 2]
Phase 1/2 trial evaluating high-concentration topical capsaicin for reducing pruritus; study status is completed.
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus [Phase 2]
Phase 2 study evaluating safety, pharmacokinetics, and preliminary efficacy of intravenous CR845 (difelikefalin) in hemodialysis patients wi…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: The Effect and Safety of Hemodialysis and Hemoperfusion on Severe Renal Osteopathy and Itching in Uremia Patients [Phase 2, Phase 3]
This trial update reports on a Phase 2/3 study evaluating the effects and safety of hemodialysis and hemoperfusion on renal osteodystrophy a…
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: A Study to Investigate the Receptor Occupancy of SK-1405 in Healthy, Caucasian, Male Subjects [Phase 1]
Phase 1 study evaluating receptor occupancy of SK-1405 in healthy, Caucasian, male subjects to explore pharmacodynamics related to pruritus;…