Pruritus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP [Phase 4]
Phase 4 trial comparing Anrikefon versus Nalfurafine for sleep quality in patients with chronic kidney disease-associated pruritus; the stud…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Bioequivalence Study of Nalfurafine Hydrochloride Orally Disintegrating Tablets on Fasting and Fed in Humans [NA]
A completed bioequivalence study of Nalfurafine hydrochloride orally disintegrating tablets evaluating fasting and fed conditions in humans …
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria [Phase 2]
Phase 2 clinical trial update reporting efficacy and safety data for povorcitinib in adults with chronic spontaneous urticaria; results comp…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Safety, Tolerability and PK of ATTO-1310 in Healthy Volunteers and Patients With Atopic Dermatitis and Patients With Chronic Pruritus [Phase 1]
This Phase 1 trial update reports on the safety, tolerability, and pharmacokinetics of ATTO-1310 in healthy volunteers and patients with ato…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Short-term Comparative Clinical Outcomes of Acupuncture and Phototherapy in Chronic Generalized Pruritus [NA]
A completed clinical trial comparing acupuncture and phototherapy for chronic generalized pruritus, reporting short-term comparative clinica…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus [Phase 2]
Phase 2 trial results evaluating dupilumab for moderate to severe chronic hepatic pruritus have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Effect of Topically Applied Olive Oil on Pruritus in Hemodialysis Patients: Pretest-posttest Model With Control Group [NA]
A completed clinical trial evaluating whether topical olive oil reduces pruritus in patients undergoing hemodialysis, using a pretest-postte…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Repetitive Applications of Pruritogens and Effects of a Cutaneous-induced Pain Stimulation on Nonhistaminergic Itch Perception [NA]
This clinical trial examined how repeated exposure to pruritogens and a cutaneous pain stimulus influences nonhistaminergic itch perception,…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Efficacy of Topical Cannabidiol for Eczema [Phase 2]
A Phase 2 clinical trial sponsored by Khon Kaen University is evaluating the efficacy of a topical cannabidiol formulation for eczema-relate…
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Treatment of Pruritus With Intramuscular Promethazine [Phase 4]
Phase 4 trial evaluating intramuscular promethazine for pruritus, including pregnancy-related pruritus, with results posted in May 2025.
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Treatment of Chronic Itch in Patients Under Arsenic Exposure With Naloxone [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated naloxone for treating chronic pruritus in patients exposed to arsenic, with results posted after comple…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Effect of Ketamine, Amitriptyline and Their Combination on Itch [NA]
Aalborg University-sponsored trial evaluating ketamine, amitriptyline, and their combination for itch has completed.
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Cross-sectional Study to Assess Prevalence and Burden of CKD-associated Pruritus in Haemodialysis Patients
Completed cross-sectional study assessing the prevalence and burden of CKD-associated pruritus in haemodialysis patients.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus [Phase 3]
A Phase 3 trial evaluating difelikefalin (CR845) for pruritus in advanced chronic kidney disease has been terminated.
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: A Study of HSK21542 in a Peritoneal Dialysis Pruritus Population. [Phase 2]
Phase 2 clinical trial update for HSK21542 in patients with pruritus associated with peritoneal dialysis.
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CLINICAL_TRIALS trial_result · 2024-02-22Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis [Phase 3]
A Phase 3 trial evaluating oral difelikefalin as an adjunct to topical corticosteroid for moderate to severe pruritus in atopic dermatitis w…
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus [Phase 2]
Phase 2 trial evaluating safety and efficacy of CR845 in chronic kidney disease patients with moderate-to-severe pruritus has completed with…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: DIalysis Symptom COntrol-Pruritus Outcome Trial [Phase 3]
A Phase 3 clinical trial assessing dialysis symptom control for pruritus in patients with end-stage renal disease has completed.
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of EP547 in healthy subjects and patients with cholestatic or uremic pru…
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT) [Phase 2]
A Phase 2 study evaluating oral difelikefalin (CR845) for moderate to severe pruritus in subjects with nontalgia paresthetica has completed.
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CLINICAL_TRIALS trial_result · 2023-03-16Clinical Trial Update: Gabapentin Versus Loratadine in Uremic Pruritus [Phase 4]
A Phase 4 trial comparing gabapentin to loratadine for uremic pruritus has completed.
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With Pruritus [Phase 2]
Phase 2 trial evaluating HSK21542 injection for pruritus in liver disease completed.
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CLINICAL_TRIALS trial_result · 2022-10-24Clinical Trial Update: Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritus [Phase 2]
Phase 2 randomized trial evaluating Aurstat versus control for pruritus associated with atopic dermatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-10-17Clinical Trial Update: A Multiple-Dose Study of BLU-5937 in Chronic Pruritus Associated With Atopic Dermatitis [Phase 2]
Phase 2 study evaluating multiple-dose BLU-5937 for chronic pruritus associated with atopic dermatitis has completed.
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CLINICAL_TRIALS trial_result · 2022-05-13Clinical Trial Update: VPD-737 for Treatment of Chronic Pruritus [Phase 2]
Phase 2 clinical trial update for VPD-737 in chronic pruritus has completed.