Pruritus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP [Phase 4]
Phase 4 trial comparing Anrikefon versus Nalfurafine for sleep quality in patients with chronic kidney disease-associated pruritus; the stud…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Assessing the Efficacy and Safety of Photobiomodulation for the Treatment of Pruritus [EARLY_Phase 1]
An early-phase 1 clinical trial at Massachusetts General Hospital is investigating photobiomodulation therapy for the treatment of pruritus …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus [Phase 2]
Clinical trial update on the safety and tolerability of difelikefalin in adolescents on haemodialysis with moderate-to-severe pruritus. The …
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Bioequivalence Study of Nalfurafine Hydrochloride Orally Disintegrating Tablets on Fasting and Fed in Humans [NA]
A completed bioequivalence study of Nalfurafine hydrochloride orally disintegrating tablets evaluating fasting and fed conditions in humans …
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria [Phase 2]
Phase 2 clinical trial update reporting efficacy and safety data for povorcitinib in adults with chronic spontaneous urticaria; results comp…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Safety, Tolerability and PK of ATTO-1310 in Healthy Volunteers and Patients With Atopic Dermatitis and Patients With Chronic Pruritus [Phase 1]
This Phase 1 trial update reports on the safety, tolerability, and pharmacokinetics of ATTO-1310 in healthy volunteers and patients with ato…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Short-term Comparative Clinical Outcomes of Acupuncture and Phototherapy in Chronic Generalized Pruritus [NA]
A completed clinical trial comparing acupuncture and phototherapy for chronic generalized pruritus, reporting short-term comparative clinica…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus [Phase 2]
Phase 2 trial updating status for TriCalm Hydrogel in treating immunotherapy-related pruritus; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A New Model to Induce Itch and Inflammation [NA]
A new experimental model to induce itch and inflammation is described, with study status not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Evaluation of the Prevalence of BP180 and BP230 Autoantibodies in the Serum of Patients With Pruritus Under Immunotherapy [NA]
A recruiting study evaluating how common BP180 and BP230 autoantibodies are in the serum of patients with chronic pruritus who have received…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Non Interventional Clinical Investigation of Ectoin Ear Spray in Skin Treatment of Outer Ear Canal Irritations
A completed non-interventional clinical study evaluated Ectoin Ear Spray for outer ear canal irritations, including pruritus, dermatitis, an…
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FDA approval · 2025-12-16FDA Approved: HYDROXYZINE HYDROCHLORIDE — Original Application (ANI Pharmaceuticals, Inc.)
FDA approves ANI Pharmaceuticals' hydroxyzine hydrochloride as a generic product via an Original Application (ANDA 219648), authorizing mark…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Mechanisms Underlying the Nocibo Effect of Contagious Itch. in Both Histaminergic and Nonhistaminergic Itch [NA]
This clinical trial entry investigates the mechanisms underlying contagious itch (nocibo effect) across histaminergic and nonhistaminergic p…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Mechanisms Underlying the Placebo Effect in Both Histaminergic and Non-histaminergic Itch [NA]
A study at Aalborg University is investigating the mechanisms underlying the placebo effect in itch (histaminergic and non-histaminergic) an…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus [Phase 2]
Phase 2 trial results evaluating dupilumab for moderate to severe chronic hepatic pruritus have been completed and results posted.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic [Phase 2]
Phase 2 clinical trial evaluating dupilumab (Dupixent) for adults with refractory post-burn pruritus, currently recruiting at an ambulatory …
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Effect of Topically Applied Olive Oil on Pruritus in Hemodialysis Patients: Pretest-posttest Model With Control Group [NA]
A completed clinical trial evaluating whether topical olive oil reduces pruritus in patients undergoing hemodialysis, using a pretest-postte…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic Itch [NA]
A Mayo Clinic-sponsored clinical trial is evaluating cervical traction to reduce GABAergic medication use for neuropathic itch (pruritus) an…
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EMA approval · 2025-07-11EMA Authorised: Kayfanda (odevixibat sesquihydrate) — Ipsen Pharma
The EMA authorised Kayfanda (odevixibat sesquihydrate) for pruritus and Alagille syndrome, manufactured by Ipsen Pharma.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Drug-induced Liver Injury: Itching Study
A clinical trial from the University of Nottingham is currently recruiting to study drug-induced liver injury and pruritus (itching).
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Role of Interleukin-13 Pathways on Pain and Itch Sensitivity ( IL-13 ) [NA]
This clinical trial update investigates how Interleukin-13 pathways influence pain and itch sensitivity, with pruritus as the condition stud…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Role of Interleukin-13 Pathways on Pain and Itch Sensitivity [NA]
A Aalborg University-sponsored clinical trial is exploring the role of Interleukin-13 pathways on pain and itch sensitivity, with recruitmen…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Identification of the Mechanism of Non-histaminergic Itch Inducing Epigenetic Changes [NA]
A Aalborg University–sponsored clinical trial is investigating the mechanism of non-histaminergic itch through epigenetic changes and is cur…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Repetitive Applications of Pruritogens and Effects of a Cutaneous-induced Pain Stimulation on Nonhistaminergic Itch Perception [NA]
This clinical trial examined how repeated exposure to pruritogens and a cutaneous pain stimulus influences nonhistaminergic itch perception,…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Efficacy of Topical Cannabidiol for Eczema [Phase 2]
A Phase 2 clinical trial sponsored by Khon Kaen University is evaluating the efficacy of a topical cannabidiol formulation for eczema-relate…