Pruritus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Treatment of Pruritus With Intramuscular Promethazine [Phase 4]
Phase 4 trial evaluating intramuscular promethazine for pruritus, including pregnancy-related pruritus, with results posted in May 2025.
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Treatment of Chronic Itch in Patients Under Arsenic Exposure With Naloxone [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated naloxone for treating chronic pruritus in patients exposed to arsenic, with results posted after comple…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Aprepitant in the Management of Immune Checkpoint Inhibitors Pruritus in Solid Cancer Patients [Phase 1]
This Phase 1 clinical trial evaluates aprepitant for management of pruritus caused by immune checkpoint inhibitors in patients with solid tu…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Reducing Itch With Hypnosis and Virtual Reality [NA]
The document reports that Universiteit Leiden has a recruiting clinical trial testing hypnosis and virtual reality to reduce itch (pruritus)…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Efficacy and Tolerance of Cannabidiol in Patients with Severe Pruritus: a Multicenter, Double-blind, Randomized, Placebo-controlled Study [Phase 3]
A Phase 3 multicenter, double-blind, randomized, placebo-controlled trial evaluating cannabidiol for severe pruritus; the study is currently…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Effect of Ketamine, Amitriptyline and Their Combination on Itch [NA]
Aalborg University-sponsored trial evaluating ketamine, amitriptyline, and their combination for itch has completed.
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Eye Movement Desensitization and Reprocessing (EMDR) to Treat Chronic Pruritus [NA]
A Basel-based clinical trial is evaluating Eye Movement Desensitization and Reprocessing (EMDR) as a treatment for chronic pruritus, with re…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Swiss Itch Registry
Clinical trial update for the Swiss Itch Registry at University Hospital Basel, currently recruiting participants for pruritus.
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CLINICAL_TRIALS withdrawal · 2024-11-22Clinical Trial Update: Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% As a New Surrogate Model of Itch [NA]
A clinical trial evaluating imiquimod 3.75% as a surrogate model for pruritus (itch) has been withdrawn.
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns [NA]
A clinical trial comparing liquid petroleum jelly (Vaseline) and olive oil to treat itching and scarring in scald burns, currently recruitin…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Cross-sectional Study to Assess Prevalence and Burden of CKD-associated Pruritus in Haemodialysis Patients
Completed cross-sectional study assessing the prevalence and burden of CKD-associated pruritus in haemodialysis patients.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica [Phase 2, Phase 3]
A Phase 2/3 study evaluating oral difelikefalin for moderate to severe pruritus in people with notalgia paresthetica has been terminated. Th…
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FDA label_change · 2024-06-11FDA Approved: HYDROCORTISONE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a Supplemental Application for HYDROCORTISONE from Aurobindo Pharma Limited, typically indicating a label change for this gener…
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CLINICAL_TRIALS withdrawal · 2024-05-07Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus [Phase 3]
Phase 3 trial evaluating difelikefalin for pruritus in advanced chronic kidney disease was terminated.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus [Phase 3]
A Phase 3 trial evaluating difelikefalin (CR845) for pruritus in advanced chronic kidney disease has been terminated.
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: A Study of HSK21542 in a Peritoneal Dialysis Pruritus Population. [Phase 2]
Phase 2 clinical trial update for HSK21542 in patients with pruritus associated with peritoneal dialysis.
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CLINICAL_TRIALS trial_result · 2024-02-22Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis [Phase 3]
A Phase 3 trial evaluating oral difelikefalin as an adjunct to topical corticosteroid for moderate to severe pruritus in atopic dermatitis w…
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus [Phase 2]
Phase 2 trial evaluating safety and efficacy of CR845 in chronic kidney disease patients with moderate-to-severe pruritus has completed with…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: DIalysis Symptom COntrol-Pruritus Outcome Trial [Phase 3]
A Phase 3 clinical trial assessing dialysis symptom control for pruritus in patients with end-stage renal disease has completed.
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FDA approval · 2023-08-17FDA Approved: HYDROXYZINE HYDROCHLORIDE — Original Application (Rising Pharma Holdings, Inc.)
FDA approved an original application for hydroxyzine hydrochloride from Rising Pharma Holdings, Inc., confirming a generic antihistamine pro…
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of EP547 in healthy subjects and patients with cholestatic or uremic pru…
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT) [Phase 2]
A Phase 2 study evaluating oral difelikefalin (CR845) for moderate to severe pruritus in subjects with nontalgia paresthetica has completed.
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CLINICAL_TRIALS trial_result · 2023-03-16Clinical Trial Update: Gabapentin Versus Loratadine in Uremic Pruritus [Phase 4]
A Phase 4 trial comparing gabapentin to loratadine for uremic pruritus has completed.
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With Pruritus [Phase 2]
Phase 2 trial evaluating HSK21542 injection for pruritus in liver disease completed.
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CLINICAL_TRIALS trial_result · 2022-10-24Clinical Trial Update: Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritus [Phase 2]
Phase 2 randomized trial evaluating Aurstat versus control for pruritus associated with atopic dermatitis has completed with results posted.