Sclerosing Cholangitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Participants With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 trial update on cenicriviroc in adults with primary sclerosing cholangitis reports preliminary efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2018-09-21Clinical Trial Update: Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating Effects [Phase 3]
Phase 3 trial evaluating oral vancomycin for primary sclerosing cholangitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC) [Phase 2]
Phase 2 trial update for obeticholic acid in primary sclerosing cholangitis has completed with results posted.
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CLINICAL_TRIALS research · 2018-05-04Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cells in Primary Sclerosing Cholangitis [Phase 1, Phase 2]
Clinical trial update on using Umbilical Cord Mesenchymal Stem Cells for primary sclerosing cholangitis in Phase 1 and Phase 2. Sponsor is F…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis [Phase 1]
This document reports the completion of a Phase 1 safety and efficacy trial evaluating ursodeoxycholic acid in pediatric primary sclerosing …
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CLINICAL_TRIALS withdrawal · 2017-07-25Clinical Trial Update: A Study Of Ursolic Acid For Primary Sclerosing Cholangitis [Phase 1]
A Phase 1 clinical trial evaluating ursolic acid for primary sclerosing cholangitis has been withdrawn (NCT03216876).
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis [Phase 1]
This clinical trial update reports the completion of a Phase 1 pilot study evaluating budesonide in patients with primary sclerosing cholang…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis [Phase 2]
Open-label Phase 2 trial evaluating safety and efficacy of LUM001 in patients with primary sclerosing cholangitis (PSC) has completed with r…
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CLINICAL_TRIALS withdrawal · 2017-03-08Clinical Trial Update: Efficacy and Safety of Vedolizumab Intravenous (IV) in the Treatment of Primary Sclerosing Cholangitis in Subjects With Underlying Inflammatory Bowel Disease [Phase 3]
Takeda's Phase 3 trial evaluating intravenous vedolizumab for primary sclerosing cholangitis in patients with inflammatory bowel disease has…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Detection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel Disease
This completed clinical trial evaluated stool DNA testing as a non-invasive method to detect advanced colorectal neoplasia in patients with …
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy [Phase 3]
The Phase 3 trial using the Digital SpyGlass system demonstrated clearance of common bile duct stones without fluoroscopy.
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CLINICAL_TRIALS research · 2016-11-15Clinical Trial Update: Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin [Phase 1]
Phase 1 clinical trial investigating vancomycin for primary sclerosing cholangitis and biliary atresia; the study is currently recruiting.
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CLINICAL_TRIALS research · 2016-09-07Clinical Trial Update: Mitomycin C Therapy for Patients With Primary Sclerosing Cholangitis [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating Mutamycin (mitomycin C) therapy for patients with Primary Sclerosing…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Norursodeoxycholic Acid in the Treatment of Primary Sclerosing Cholangitis [Phase 2]
A Phase 2 clinical trial evaluating norursodeoxycholic acid for primary sclerosing cholangitis has completed. The trial was sponsored by Dr.…
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating the combination of ursodeoxycholic acid (UDCA) and all-trans…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing Cholangitis
A completed clinical trial evaluated surgical reconstruction for patients with ulcerative colitis and primary sclerosing cholangitis.
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CLINICAL_TRIALS research · 2016-03-08Clinical Trial Update: The Effect of Bezafibrate on Cholestatic Itch [Phase 3]
Phase 3 trial investigating bezafibrate for reducing cholestatic itch in patients with cholestatic liver diseases; status is not specified.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin [Phase 1]
Phase 1 study assessing the effects of vancomycin on gastrointestinal microbiota in patients with Primary Sclerosing Cholangitis and Biliary…
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CLINICAL_TRIALS research · 2016-02-09Clinical Trial Update: Development of a Patient-Reported Outcome Measure to Assess Symptoms in Patients With Primary Sclerosing Cholangitis (PSC)
This trial update describes the development of a patient-reported outcome measure to assess symptoms in patients with primary sclerosing cho…
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & Cholangitis
A completed clinical trial comparing conventional colonoscopy to endoscopic autofluorescence imaging (AFI) and narrow-band imaging (NBI) for…
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CLINICAL_TRIALS trial_result · 2015-11-16Clinical Trial Update: Effect and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis Patients [Phase 4]
This clinical trial update reports on the effects and safety of oral vancomycin in patients with primary sclerosing cholangitis (Phase 4).
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CLINICAL_TRIALS withdrawal · 2015-04-28Clinical Trial Update: The Value of CT Cholangiography in Primary Sclerosing Cholangitis [Phase 2]
A Phase 2 clinical trial evaluating CT cholangiography for primary sclerosing cholangitis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-04-27Clinical Trial Update: Endomicroscopy in Primary Sclerosing Cholangitis Related Inflammatory Bowel Disease Surveillance
This completed clinical trial evaluated the use of endomicroscopy for surveillance in patients with primary sclerosing cholangitis and infla…
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CLINICAL_TRIALS trial_result · 2015-03-11Clinical Trial Update: Evaluation of DHA for the Treatment of PSC [Phase 1]
Phase 1 trial evaluating docosahexaenoic acid (DHA) for primary sclerosing cholangitis, with colitis as a related condition, has completed.
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT [Phase 1]
Phase 1 study assessing biliary excretion of conjugated bile acids in humans using 11C-cholylsarcosine PET/CT; the trial was completed and r…