Sclerosing Cholangitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: CM-101 in PSC Patients -The SPRING Study [Phase 2]
Phase 2 clinical trial results for CM-101 in patients with primary sclerosing cholangitis (PSC) have been completed and results posted.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach
NIDDK-funded clinical trial is investigating the mechanisms of primary sclerosing cholangitis through multidisciplinary, integrative researc…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Vancomycin for Primary Sclerosing Cholangitis [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating vancomycin for primary sclerosing cholangitis has been terminated, with results posted.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis [Phase 3]
Ipsen is conducting a Phase 3 clinical trial to evaluate the efficacy and safety of elafibranor in adults with primary sclerosing cholangiti…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis. [Phase 2]
Ipsen is conducting a Phase 2 study to assess the safety and effectiveness of Elafibranor in adults with Primary Sclerosing Cholangitis, and…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Colangioids to Define the Genetic Factors Involved in Atypical Primary Sclerosing Cholangitis [NA]
Clinical trial titled 'Colangioids to Define the Genetic Factors Involved in Atypical Primary Sclerosing Cholangitis' is investigating genet…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
A recruiting clinical trial is examining the liver-gut axis by identifying liver disease–specific microbiome patterns. The study covers auto…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Fecal Microbiota Transplantation for Primary Sclerosing Cholangitis - Randomized Study Versus Sham Transplantation [Phase 2]
Phase 2 randomized trial assessing fecal microbiota transplantation versus sham transplantation for primary sclerosing cholangitis; the stud…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: CS0159 in Chinese Patients With PSC (Primary Sclerosing Cholangitis) [Phase 2]
A Phase 2 clinical trial evaluating CS0159 in Chinese patients with primary sclerosing cholangitis is listed as active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Sulfasalazine for the Treatment of Primary Sclerosing Cholangitis [Phase 2]
This update reports the completion of a Phase 2 clinical trial evaluating sulfasalazine for the treatment of Primary Sclerosing Cholangitis.
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: A Pilot Study Examining Diet in Primary Sclerosing Cholangitis [NA]
A completed pilot trial evaluating dietary interventions in Primary Sclerosing Cholangitis. The study explored whether diet modifications co…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Study of TAK-781 in Healthy Volunteers and in Participants With Non-Cirrhotic Primary Sclerosing Cholangitis (PSC) [Phase 1]
Phase 1 clinical trial evaluating TAK-781 in healthy volunteers and in participants with non-cirrhotic primary sclerosing cholangitis; curre…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study [EARLY_Phase 1]
An early-phase 1 trial at Stanford is evaluating statin therapy for primary sclerosing cholangitis using a multi-omics approach. The study i…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)
A global prospective observational cohort study called WIND-PSC is recruiting adults with primary sclerosing cholangitis. The sponsor is PSC…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Biobank for Cholestatic Liver Diseases.
Mayo Clinic is recruiting for a biobank study of cholestatic liver diseases, including primary sclerosing cholangitis and primary biliary ch…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
A Mayo Clinic-sponsored study aims to characterize biliary cell-derived organoids from bile samples of patients with primary sclerosing chol…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the efficacy and safety of Volixibat for itching in patients with Primary Sc…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC) [Phase 2]
Phase 2a study evaluating the safety, tolerability, and pharmacokinetics of PLN-74809 in patients with primary sclerosing cholangitis has co…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis [Phase 2]
Phase 2 clinical trial evaluating vancomycin efficacy in patients with ulcerative colitis and primary sclerosing cholangitis; the study stat…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Gluten-free Diet in PSC and IBD [NA]
Clinical trial update describing an active-not-recruiting study evaluating a gluten-free diet in people with primary sclerosing cholangitis …
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Repeatability and Reproducibility of Multiparametric MRI
A clinical trial update reports on the repeatability and reproducibility of multiparametric MRI for evaluating liver diseases across several…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Study of SIPLIZUMAB in AILD and LT Patients [Phase 1]
Phase 1 clinical trial of SIPLIZUMAB for autoimmune liver disease and liver transplant-related conditions is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Detoxification of the Liver In PSC (Dolphin) [Phase 2]
A Phase 2 clinical trial update (Dolphin) for detoxification of the liver in primary sclerosing cholangitis, sponsored by Brigham and Women'…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC [Phase 2]
Phase 2 study LB-P8 in Primary Sclerosing Cholangitis is currently recruiting to assess safety and efficacy.
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: PET/MRI of Primary Sclerosing Cholangitis
A PET/MRI study in primary sclerosing cholangitis is planned but not yet recruiting.