Sclerosing Cholangitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: LEOPARD Prospective Validation Cohort 1
This clinical trial update describes the LEOPARD prospective validation cohort 1 by Assistance Publique - Hôpitaux de Paris and lists condit…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: MRI Based Biomarkers in Pediatric Autoimmune Liver Disease
An ongoing pediatric study evaluating MRI-based biomarkers for autoimmune liver diseases, including autoimmune hepatitis and primary scleros…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease
A clinical trial is evaluating MRI biomarkers as predictors of clinical outcomes in pediatric autoimmune liver disease, including autoimmune…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Endoscopy and Primary Sclerosing Cholangitis
A clinical trial evaluating the use of endoscopy in patients with Primary Sclerosing Cholangitis has completed.
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Spanish Registry of Quality Indicators and Adverse Events of Endoscopic Retrograde Cholangiopancreatography
This entry describes the Spanish Registry of Quality Indicators and Adverse Events for Endoscopic Retrograde Cholangiopancreatography (ERCP)…
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CLINICAL_TRIALS research · 2024-08-29Clinical Trial Update: A Microdose Trial Investigating Binding of [68Ga]Ga-DOTA-CYS-ATH001 in Healthy Subjects and Different Patient Groups. [EARLY_Phase 1]
Early-phase microdose clinical trial evaluating binding of the radiotracer [68Ga]Ga-DOTA-CYS-ATH001 in healthy volunteers and patients with …
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: norUrsodeoxycholic Acid vs Placebo in PSC [Phase 3]
A Phase 3 trial evaluating norUrsodeoxycholic Acid (norUDCA) vs placebo for Primary Sclerosing Cholangitis. The study is currently ACTIVE_NO…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Selected Mesenchymal Stromal Cells to Reduce Inflammation in Patients With PSC and AIH [Phase 1, Phase 2]
An update on an ongoing Phase 1/2 trial evaluating selected mesenchymal stromal cells to reduce liver inflammation in patients with primary …
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: CM-101 in PSC Patients -The SPRING Study [Phase 2]
Phase 2 clinical trial update for CM-101 in patients with primary sclerosing cholangitis (PSC) is active not recruiting.
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: Study of Cilofexor in Adults With Primary Sclerosing Cholangitis [Phase 3]
A Phase 3 trial of cilofexor in adults with primary sclerosing cholangitis was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis [Phase 1]
Phase 1 trial assessing safety and tolerability of cilofexor in participants with primary sclerosing cholangitis and compensated cirrhosis; …
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Evaluation of the Safety and Efficacy of HK-660S in Patients With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of HK-660S in patients with primary sclerosing cholangitis has completed.
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CLINICAL_TRIALS trial_result · 2022-10-17Clinical Trial Update: A Research Study to Evaluate Safety and Efficacy of DUR-928 in Subjects With Primary Sclerosing Cholangitis (PSC) [Phase 2]
Phase 2 study evaluating safety and efficacy of DUR-928 in subjects with primary sclerosing cholangitis was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapy [Phase 3]
Phase 3 clinical trial evaluating 24 months of bezafibrate for primary sclerosing cholangitis with persistent cholestasis despite ursodeoxyc…
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: A POC and Dose-Ranging Study of HTD1801 in PSC Patients [Phase 2]
A Phase 2 dose-ranging and proof-of-concept study of HTD1801 in Primary Sclerosing Cholangitis (PSC) has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 trial of low-dose all-trans retinoic acid in primary sclerosing cholangitis was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases [Phase 2]
Phase 2 clinical trial evaluating low-dose IL-2 to induce regulatory T cells in various autoimmune and inflammatory diseases; trial complete…
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Vidofludimus Calcium for Primary Sclerosing Cholangitis [Phase 2]
Phase 2 clinical trial of vidofludimus calcium in primary sclerosing cholangitis completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Trial of High-dose Urso in Primary Sclerosing Cholangitis [Phase 2, Phase 3]
Phase 2/3 trial of high-dose ursodeoxycholic acid in primary sclerosing cholangitis was terminated with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic Function [Phase 1]
Phase 1 study reporting pharmacokinetics and pharmacodynamics of cilofexor in adults with normal and impaired hepatic function; completed wi…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating the safety and efficacy of curcumin in patients with primary sclerosing cholangitis has completed with…
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CLINICAL_TRIALS trial_result · 2019-10-22Clinical Trial Update: Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Adults With Primary Sclerosing Cholangitis (PSC) [Phase 2]
Phase 2 trial update for simtuzumab (GS-6624) in adults with primary sclerosing cholangitis (PSC) completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Fecal Microbiota Transplantation for the Treatment of Primary Sclerosing Cholangitis. [Phase 1, Phase 2]
Clinical trial update on fecal microbiota transplantation for primary sclerosing cholangitis (phases 1 and 2) completed with results posted …
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CLINICAL_TRIALS trial_result · 2019-05-03Clinical Trial Update: A Trial of BTT1023 in Patients With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 clinical trial of BTT1023 in patients with primary sclerosing cholangitis has completed.
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CLINICAL_TRIALS trial_result · 2019-03-12Clinical Trial Update: Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis [Phase 2]
Phase 2 trial evaluating cilofexor in adults with primary sclerosing cholangitis without cirrhosis has completed; results posted in 2019.