Immunodeficiency
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-16Clinical Trial Update: Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases [Phase 3]
A Phase 3 trial evaluating the pharmacokinetics, efficacy, tolerability, and safety of subcutaneous Newnorm immunoglobulin in patients with …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Detection and Characterization of Infections and Infection Susceptibility
A National Institute of Allergy and Infectious Diseases study is currently recruiting to detect and characterize infections and infection su…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations [Phase 2]
A Phase 2 clinical trial is investigating allogeneic hematopoietic stem cell transplantation for patients with GATA2 mutations, currently in…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders
A National Institute of Allergy and Infectious Diseases trial update describes establishing fibroblast-derived cell lines from skin biopsies…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: An Open-label, Multicenter Study to Assess the Pharmacokinetics (PK), Safety, and Tolerability of Subcutaneous IgPro20 in Immunoglobulin (IG) Treatment-naïve Participants With Primary Immunodeficiency (PID) [Phase 4]
An open-label, multicenter Phase 4 study to evaluate the pharmacokinetics, safety, and tolerability of subcutaneous IgPro20 in treatment-naï…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Screening Protocol for Genetic Diseases of Allergic Inflammation
Completed clinical trial update describing a screening protocol for genetic diseases involved in allergic inflammation.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: NIAID Centralized Sequencing Protocol
This clinical trial update describes the NIAID centralized sequencing protocol, a study in recruitment to develop standardized sequencing ap…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Impact of Thymectomy on Immunity in Infants After Cardiac Surgery [NA]
A Nantes University Hospital trial is evaluating how thymectomy during infancy after cardiac surgery affects immune function; the study is c…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD45RA-depleted stem cell addback to prevent viral or fungal infections following TCRab/CD19-deplet…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary Immunodeficiencies
This study involves send-in sample collection to genetically and immunologically characterize primary immunodeficiencies.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Longitudinal Prognosis of Lymphoproliferative Manifestations in Primary Immunodeficiencies
The study aims to characterize the longitudinal prognosis of lymphoproliferative manifestations in patients with primary immunodeficiencies.…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Metabolic Profiling of Immune Responses in Immune-mediated Diseases
A clinical trial update from NIAID announces ongoing recruitment for a study investigating metabolic profiling of immune responses in immune…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma [Phase 3]
A Phase 3 study evaluating Gammagard Liquid (intravenous immunoglobulin 10%) to prevent infections in adults with multiple myeloma is curren…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Natural History of Noncirrhotic Portal Hypertension
This clinical trial update notes that a NIDDK-supported study is investigating the natural history of idiopathic noncirrhotic portal hyperte…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Opioid, HIV and Immune System [Phase 4]
University of Miami is conducting a Phase 4 trial related to opioid, HIV, and the immune system, currently active but not recruiting, in pat…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Sequential Transplantation of UCBSCs and Islet Cells in Children and Adolescents With Monogenic Immunodeficiency T1DM [NA]
Clinical trial investigating sequential transplantation of umbilical cord blood stem cells and islet cells in children and adolescents with …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Primitive Immunodeficiency and Pregnancy
A completed clinical trial investigated management of primary immunodeficiency during pregnancy, sponsored by Assistance Publique - Hôpitaux…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy Trial [Phase 2]
A Phase 2 randomized factorial trial to optimize antiviral therapy in immunocompromised COVID-19 patients. The study is currently recruiting…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Database Survey to Evaluate the Safety of Immune Globulin Subcutaneous (Human), 20% Solution in Participants With Primary Immunodeficiency
Takeda reports a database survey to evaluate the safety of Immune Globulin Subcutaneous (Human), 20% Solution in participants with primary i…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC [EARLY_Phase 1]
An early-phase expanded-access protocol evaluating CD3+/CD19+ depleted peripheral blood stem cells for leukemia and related immunodeficiency…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Real-world Usage of HyQvia in Multiple Myeloma Adults With Secondary Immunodeficiency
This clinical trial will investigate the real-world usage of HyQvia in adults with multiple myeloma and secondary immunodeficiency. The stud…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients [Phase 2]
This is a Phase 2 clinical trial evaluating optimized antiviral therapy for COVID-19 in immunocompromised patients; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Immunoglobulin G Therapy Dose Optimization
A completed Rutgers-sponsored clinical trial evaluating dose optimization of immunoglobulin G therapy.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: V-IMMUNE: A Novel Immunoglobulin Therapy for Immunodeficiency [Phase 3]
A Phase 3 clinical trial evaluating V-IMMUNE, a novel immunoglobulin therapy, for primary immunodeficiencies including agammaglobulinemia; r…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC
Clinical trial update describing a data collection study of patients with non-malignant disorders undergoing umbilical cord blood transplant…