Immunodeficiency
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CLINICAL_TRIALS trial_result · 2026-07-16Clinical Trial Update: Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases [Phase 3]
A Phase 3 trial evaluating the pharmacokinetics, efficacy, tolerability, and safety of subcutaneous Newnorm immunoglobulin in patients with …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Natural History of Noncirrhotic Portal Hypertension
This clinical trial update notes that a NIDDK-supported study is investigating the natural history of idiopathic noncirrhotic portal hyperte…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Primitive Immunodeficiency and Pregnancy
A completed clinical trial investigated management of primary immunodeficiency during pregnancy, sponsored by Assistance Publique - Hôpitaux…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Immunoglobulin G Therapy Dose Optimization
A completed Rutgers-sponsored clinical trial evaluating dose optimization of immunoglobulin G therapy.
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, France [NA]
A completed clinical trial update assessing the prevalence of bronchiectasis in patients with primary humoral immunodeficiency, including CV…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With (COVID-19) [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial evaluating multiple natural products and compounds (Omega-3, Nigella sativa, Indian costus, quinine, anise se…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Primary Immunodeficiencies and Obstetrical Neuraxial Anaesthesia
This completed clinical trial evaluated safety issues related to obstetrical neuraxial anesthesia in patients with primary immunodeficiencie…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies
Completed clinical trial examining upper airway manifestations in primary ciliary dyskinesia and primary immunodeficiencies.
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection [Phase 2]
Phase 2 trial of EBV-specific cytotoxic T-lymphocytes for refractory Epstein-Barr virus infection is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant [Phase 1, Phase 2]
Results from a Phase 1/2 trial of bilateral orthotopic lung transplantation with bone marrow transplantation in primary immunodeficiency hav…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Expanded Access Protocol Thymus Transplantation [Phase 4]
Expanded Access Protocol Thymus Transplantation (Phase 4) has posted results for patients with poor thymic function and immunodeficiency. Th…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Aerobic Exercises Versus Laser Puncture on Immune Response Following Neck Lymph Node Dissection [NA]
A completed clinical trial comparing aerobic exercise versus laser puncture to evaluate immune response after neck lymph node dissection.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID) [Phase 3]
Phase 3 trial of TAK-771 in Japanese participants with primary immunodeficiency has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and Dysregulations
A completed clinical trial evaluating COVID-19 vaccination outcomes in individuals with and without immunodeficiencies and immune dysregulat…
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: PREP (Pre-Exposure Prophylaxis) of COVID-19
This is a completed clinical trial update for PREP (Pre-Exposure Prophylaxis) of COVID-19. The study involves individuals with immunodeficie…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Rapamycin Treatment for Activated Phosphoinositide 3-Kinase δ Syndrome [Phase 1, Phase 2]
This document reports the completion of a Phase 1/2 trial evaluating rapamycin for Activated PI3K-delta syndrome (APDS), a primary immunodef…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Nutrition, Immunity, and Covid-19 in Obese People [Phase 2]
This is a Phase 2 clinical trial update from Indonesia University evaluating how nutrition and vitamin D status influence immunity in obese …
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study [Phase 1, Phase 2]
Long-term follow-up update from BP-004 study (Phase 1/Phase 2) by Bellicum Pharmaceuticals; study status TERMINATED with results posted in 2…
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CLINICAL_TRIALS trial_result · 2023-08-07Clinical Trial Update: A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency [Phase 4]
Phase 4 trial evaluating IGSC 20% biweekly dosing in treatment-experienced and loading/maintenance dosing in treatment-naïve participants wi…
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral Immunodeficiency [Phase 3]
Phase 3 study comparing IVIG-PEG to standard Gamunex-C in people with primary immunodeficiency; results completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-01-04Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant [Phase 1, Phase 2]
A phase 1/2 safety study evaluating gene-modified donor T-cells after TCRαβ+ depleted stem cell transplant was terminated; results were post…
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CLINICAL_TRIALS trial_result · 2021-08-20Clinical Trial Update: Study of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10% [Phase 3]
Phase 3 trial update for ProMetic BioTherapeutics' intravenous immunoglobulin (10%) in primary immunodeficiency has completed with results p…
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CLINICAL_TRIALS trial_result · 2021-06-29Clinical Trial Update: Non-Interventional Study on the Tolerability and Efficacy of IVIG
A completed non-interventional study evaluating tolerability and efficacy of Octagam IVIG in primary and secondary immunodeficiency and othe…
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Preemptive Use of Convalescent Plasma for High-risk Patients With COVID-19 [Phase 3]
A Phase 3 clinical trial update on preemptive use of convalescent plasma for high-risk COVID-19 patients, status not yet determined.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID) [Phase 3]
A Phase 3 study evaluating Kedrion IVIG 10% for efficacy and safety in subjects with primary immunodeficiency shows completed status with re…