Immunodeficiency
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Detection and Characterization of Infections and Infection Susceptibility
A National Institute of Allergy and Infectious Diseases study is currently recruiting to detect and characterize infections and infection su…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations [Phase 2]
A Phase 2 clinical trial is investigating allogeneic hematopoietic stem cell transplantation for patients with GATA2 mutations, currently in…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders
A National Institute of Allergy and Infectious Diseases trial update describes establishing fibroblast-derived cell lines from skin biopsies…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: An Open-label, Multicenter Study to Assess the Pharmacokinetics (PK), Safety, and Tolerability of Subcutaneous IgPro20 in Immunoglobulin (IG) Treatment-naïve Participants With Primary Immunodeficiency (PID) [Phase 4]
An open-label, multicenter Phase 4 study to evaluate the pharmacokinetics, safety, and tolerability of subcutaneous IgPro20 in treatment-naï…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Screening Protocol for Genetic Diseases of Allergic Inflammation
Completed clinical trial update describing a screening protocol for genetic diseases involved in allergic inflammation.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: NIAID Centralized Sequencing Protocol
This clinical trial update describes the NIAID centralized sequencing protocol, a study in recruitment to develop standardized sequencing ap…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Impact of Thymectomy on Immunity in Infants After Cardiac Surgery [NA]
A Nantes University Hospital trial is evaluating how thymectomy during infancy after cardiac surgery affects immune function; the study is c…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD45RA-depleted stem cell addback to prevent viral or fungal infections following TCRab/CD19-deplet…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary Immunodeficiencies
This study involves send-in sample collection to genetically and immunologically characterize primary immunodeficiencies.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Longitudinal Prognosis of Lymphoproliferative Manifestations in Primary Immunodeficiencies
The study aims to characterize the longitudinal prognosis of lymphoproliferative manifestations in patients with primary immunodeficiencies.…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Metabolic Profiling of Immune Responses in Immune-mediated Diseases
A clinical trial update from NIAID announces ongoing recruitment for a study investigating metabolic profiling of immune responses in immune…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma [Phase 3]
A Phase 3 study evaluating Gammagard Liquid (intravenous immunoglobulin 10%) to prevent infections in adults with multiple myeloma is curren…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Opioid, HIV and Immune System [Phase 4]
University of Miami is conducting a Phase 4 trial related to opioid, HIV, and the immune system, currently active but not recruiting, in pat…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Sequential Transplantation of UCBSCs and Islet Cells in Children and Adolescents With Monogenic Immunodeficiency T1DM [NA]
Clinical trial investigating sequential transplantation of umbilical cord blood stem cells and islet cells in children and adolescents with …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy Trial [Phase 2]
A Phase 2 randomized factorial trial to optimize antiviral therapy in immunocompromised COVID-19 patients. The study is currently recruiting…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Database Survey to Evaluate the Safety of Immune Globulin Subcutaneous (Human), 20% Solution in Participants With Primary Immunodeficiency
Takeda reports a database survey to evaluate the safety of Immune Globulin Subcutaneous (Human), 20% Solution in participants with primary i…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC [EARLY_Phase 1]
An early-phase expanded-access protocol evaluating CD3+/CD19+ depleted peripheral blood stem cells for leukemia and related immunodeficiency…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Real-world Usage of HyQvia in Multiple Myeloma Adults With Secondary Immunodeficiency
This clinical trial will investigate the real-world usage of HyQvia in adults with multiple myeloma and secondary immunodeficiency. The stud…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients [Phase 2]
This is a Phase 2 clinical trial evaluating optimized antiviral therapy for COVID-19 in immunocompromised patients; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: V-IMMUNE: A Novel Immunoglobulin Therapy for Immunodeficiency [Phase 3]
A Phase 3 clinical trial evaluating V-IMMUNE, a novel immunoglobulin therapy, for primary immunodeficiencies including agammaglobulinemia; r…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC
Clinical trial update describing a data collection study of patients with non-malignant disorders undergoing umbilical cord blood transplant…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT [Phase 2]
Phase 2 study evaluating reduced-intensity conditioning for non-malignant disorders undergoing umbilical cord blood transplantation (UCBT), …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies
This clinical trial aims to characterize autoreactive B lymphocytes in autoimmune diseases and immune deficiencies. The study status is not …
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Quality of Life Among Children With Inborn Error of Immunity
This clinical trial from Sohag University will assess quality of life in children with primary immunodeficiency, but the study is not yet re…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Severe Immune Cytopenia Registry Www.Sic-reg.Org
This entry provides a completed update on the Severe Immune Cytopenia Registry (SIC-reg), sponsored by the Medical University of Graz, cover…