Preterm Premature Rupture of Membranes
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation [Phase 3]
This update covers a Phase 3 trial evaluating tocolysis for managing preterm premature rupture of membranes before 34 weeks gestation; the s…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: HOME: Home Monitoring of High-risk Pregnancies
HOME: Home Monitoring of High-risk Pregnancies is currently enrolling by invitation. The study focuses on hypertensive disorders of pregnanc…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT) [Phase 4]
A Phase 4 clinical trial (iPROMPT) is evaluating prophylactic antimicrobial therapy to improve management of preterm premature rupture of me…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture of Membranes : A French Multicenter Cohort Study
This clinical trial update describes a multicenter French cohort study examining how common ESBL-producing Enterobacteriaceae carriage is in…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Antenatal Breastmilk Expression in Pregnant Women at High Risk of Preterm Birth [NA]
A clinical trial investigating antenatal breastmilk expression in pregnant women at high risk of preterm birth, sponsored by Odense Universi…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes [Phase 3]
Phase 3 clinical trial comparing erythromycin versus azithromycin for preterm prelabor rupture of membranes is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM [Phase 4]
A Phase 4 trial by Eastern Virginia Medical School is recruiting to compare induction of labor using oxytocin with a Foley catheter versus o…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: TAILORED Therapeutic Regime in Patients With Preterm Premature Rupture Of Membranes to Prolong Pregnancy, Improve Maternal and Neonatal Outcomes, and Reduce Antibiotic Burden [Phase 3]
Phase 3 clinical trial evaluating a tailored therapeutic regimen for women with preterm premature rupture of membranes to prolong pregnancy …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Trans-perineal Ultrasound in Assessment of PPROMs
A clinical trial from Ain Shams University evaluating trans-perineal ultrasound for assessing preterm premature rupture of membranes has com…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Latency Antibiotics for Previable Rupture Of Membranes Trial [Phase 4]
Phase 4 trial evaluating latency antibiotics for previable preterm premature rupture of membranes; the study is currently not yet recruiting…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Preterm Rupture of Membranes Optimising Antibiotics Trial [NA]
University of Melbourne is conducting a clinical trial to optimise antibiotic therapy for preterm premature rupture of membranes (PPROM). Th…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: MIRACLE of LIFE Study
Mirvie's MIRACLE of LIFE clinical trial update indicates the study is currently active but not recruiting, focusing on pregnancy outcomes re…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus [NA]
This clinical trial is evaluating the physiological and psychological effects of music therapy in pregnant women and their fetuses. The stud…
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CLINICAL_TRIALS research · 2018-03-13Clinical Trial Update: Best Cutoff Value of Lactate Concentration in Vaginal Fluid to Predict Time of Spontaneous Onset of Labor in PPROM
A clinical trial investigating the best cutoff value of vaginal fluid lactate concentration to predict the time to spontaneous onset of labo…
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CLINICAL_TRIALS research · 2018-03-07Clinical Trial Update: Myometrial Thickness as a Predictor for the Latency Interval in PPROM
A Cairo University-sponsored clinical trial investigates whether myometrial thickness can predict the latency interval in preterm premature …
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CLINICAL_TRIALS research · 2017-10-11Clinical Trial Update: mtDNA as Novel Biomarker for Intra-amniotic Infection
This clinical trial update investigates mitochondrial DNA as a novel biomarker for intra-amniotic infection in pregnancies affected by prete…
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CLINICAL_TRIALS research · 2016-12-29Clinical Trial Update: Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes [Phase 4]
Clinical trial update for a Phase 4 study comparing two antibiotic prophylaxis protocols in preterm premature rupture of membranes.
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CLINICAL_TRIALS research · 2015-12-18Clinical Trial Update: The Relation Between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes
A clinical trial sponsored by Ain Shams Maternity Hospital is investigating the relationship between serum ascorbic acid concentration and p…
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CLINICAL_TRIALS research · 2015-09-14Clinical Trial Update: Preterm Premature Rupture of Membranes, Outpatient Management vs Inpatient Management [NA]
Clinical trial update for NCT02548013 comparing outpatient versus inpatient management of preterm premature rupture of membranes. The status…
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CLINICAL_TRIALS research · 2014-04-04Clinical Trial Update: Evaluation of the Role of Plasma Procalcitonin in Prediction of Intra-amniotic Infection in Preterm Premature Rupture of Membrane
This clinical trial evaluates whether plasma procalcitonin can predict intra-amniotic infection in women with preterm premature rupture of m…
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CLINICAL_TRIALS research · 2014-02-24Clinical Trial Update: Pomegranate to Reduce Maternal and Fetal Oxidative Stress and to Improve Outcome in Pregnancies Complicated With Preterm Premature Rupture of Membranes [NA]
Clinical trial investigating whether pomegranate supplementation reduces maternal/fetal oxidative stress and improves outcomes in pregnancie…
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CLINICAL_TRIALS research · 2013-03-05Clinical Trial Update: AL-SENSE 1-Step - Determination of Product Specificity [NA]
Clinical trial update for AL-SENSE 1-Step assessing product specificity in the context of preterm premature rupture of membranes. The curren…
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CLINICAL_TRIALS research · 2012-04-24Clinical Trial Update: Pomegranate to Reduce Maternal and Fetal Oxidative Stress and Improve Outcome in Pregnancies Complicated With Preterm Premature Rupture of the Membranes [NA]
A clinical trial is evaluating whether pomegranate can reduce maternal and fetal oxidative stress and improve outcomes in pregnancies affect…
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CLINICAL_TRIALS research · 2010-06-29Clinical Trial Update: Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery [Phase 3]
A Phase 3 trial update for Va-Sense evaluating weekly screening and treatment to reduce infective complications, abortion, and preterm deliv…