Preterm Premature Rupture of Membranes
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CLINICAL_TRIALS trial_result · 2026-06-30Clinical Trial Results: Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity? [Phase 2, Phase 3]
A Phase 2/3 trial investigated whether a rescue course of betamethasone in pregnant women with preterm premature rupture of membranes reduce…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation [Phase 3]
This update covers a Phase 3 trial evaluating tocolysis for managing preterm premature rupture of membranes before 34 weeks gestation; the s…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Biochemical and Histological Changes in Pregnant Women With Preterm Premature Rupture of Membrane
A completed clinical trial update evaluating biochemical and histological changes in pregnant women with preterm premature rupture of membra…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial [Phase 4]
A Phase 4 pilot randomized trial compares induction of labor using combined mifepristone and misoprostol versus misoprostol alone in nonviab…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: HOME: Home Monitoring of High-risk Pregnancies
HOME: Home Monitoring of High-risk Pregnancies is currently enrolling by invitation. The study focuses on hypertensive disorders of pregnanc…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Unlocking New Avenues: Azithromycin Vs Erythromycin in Pre-term, Pre-mature Rupture of Membrane Management [Phase 1]
Phase 1 trial comparing azithromycin and erythromycin for the management of preterm premature rupture of membranes has completed.
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT) [Phase 4]
A Phase 4 clinical trial (iPROMPT) is evaluating prophylactic antimicrobial therapy to improve management of preterm premature rupture of me…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Digital vs. Speculum Exams for PPROM [NA]
A clinical trial comparing digital versus speculum exams for preterm premature rupture of membranes is currently recruiting. Sponsored by Wa…
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: The Psychological Experience of Pathological Pregnancy. Study of the Case of Premature Rupture of Membranes and Evaluation of the Impact of Hypnosis Support [NA]
This clinical trial update reports that a study examining the psychological experience of pathological pregnancy—specifically premature rupt…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture of Membranes : A French Multicenter Cohort Study
This clinical trial update describes a multicenter French cohort study examining how common ESBL-producing Enterobacteriaceae carriage is in…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Antenatal Breastmilk Expression in Pregnant Women at High Risk of Preterm Birth [NA]
A clinical trial investigating antenatal breastmilk expression in pregnant women at high risk of preterm birth, sponsored by Odense Universi…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes [Phase 3]
Phase 3 clinical trial comparing erythromycin versus azithromycin for preterm prelabor rupture of membranes is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Effects of Different Antibiotic Regimens in Preterm Premature Rupture of Membranes [NA]
This clinical trial update reports the completion of a study comparing different antibiotic regimens for preterm premature rupture of membra…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM [Phase 4]
A Phase 4 trial by Eastern Virginia Medical School is recruiting to compare induction of labor using oxytocin with a Foley catheter versus o…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: TAILORED Therapeutic Regime in Patients With Preterm Premature Rupture Of Membranes to Prolong Pregnancy, Improve Maternal and Neonatal Outcomes, and Reduce Antibiotic Burden [Phase 3]
Phase 3 clinical trial evaluating a tailored therapeutic regimen for women with preterm premature rupture of membranes to prolong pregnancy …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Trans-perineal Ultrasound in Assessment of PPROMs
A clinical trial from Ain Shams University evaluating trans-perineal ultrasound for assessing preterm premature rupture of membranes has com…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Latency Antibiotics for Previable Rupture Of Membranes Trial [Phase 4]
Phase 4 trial evaluating latency antibiotics for previable preterm premature rupture of membranes; the study is currently not yet recruiting…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Preterm Rupture of Membranes Optimising Antibiotics Trial [NA]
University of Melbourne is conducting a clinical trial to optimise antibiotic therapy for preterm premature rupture of membranes (PPROM). Th…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Amniochorionic Membrane Cells in the Maternal Blood as a Biomarker for Preterm Birth
The study evaluating amniochorionic membrane cells in maternal blood as a biomarker for preterm birth has completed.
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: MIRACLE of LIFE Study
Mirvie's MIRACLE of LIFE clinical trial update indicates the study is currently active but not recruiting, focusing on pregnancy outcomes re…
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CLINICAL_TRIALS withdrawal · 2024-10-15Clinical Trial Update: Erythromycin Versus Azithromycin in Preterm Premature Rupture of Membranes [Phase 3]
A Phase 3 trial comparing erythromycin and azithromycin for preterm premature rupture of membranes was withdrawn.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus [NA]
This clinical trial is evaluating the physiological and psychological effects of music therapy in pregnant women and their fetuses. The stud…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Treatment of ppROM With Erythromycin vs. Azithromycin Trial [Phase 3]
Phase 3 trial comparing erythromycin and azithromycin for preterm premature rupture of membranes has been terminated. Results have been post…
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CLINICAL_TRIALS trial_result · 2024-01-26Clinical Trial Update: Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity? [Phase 2, Phase 3]
A phase 2/3 trial evaluating a rescue course of betamethasone in pregnant women with preterm premature rupture of membranes (PPROM) to reduc…
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Azithromycin Dose and PPROM Treatment: a Pilot Randomized Controlled Trial [Phase 4]
A Phase 4 pilot randomized controlled trial evaluating azithromycin dose strategies for treating preterm premature rupture of membranes (PPR…