Portal Hypertension
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Sign up freeTop drugs studied for this disease
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FDA approval · 2019-09-13FDA Approved: NADOLOL — Original Application (VGYAAN Pharmaceuticals LLC)
The FDA approved Nadolol as a generic product through an Original Application (ANDA) from VGYAAN Pharmaceuticals LLC. Nadolol is a non-selec…
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CLINICAL_TRIALS trial_result · 2019-07-12Clinical Trial Update: A Study to Investigate the Safety and Effect of the Study Drug (FE 204205) in Patients With Cirrhotic Portal Hypertension [Phase 1]
Phase 1 trial assessing safety and effect of FE 204205 in patients with portal hypertension was terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resection [Phase 3]
Phase 3 clinical trial investigating somatostatin's role in hepatic hemodynamics for patients undergoing liver resection.
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CLINICAL_TRIALS research · 2019-05-14Clinical Trial Update: Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension [Phase 2, Phase 3]
A clinical trial update evaluating propranolol, carvedilol, and rosuvastatin for prevention of variceal bleeding in cirrhotic portal hyperte…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Serelaxin To Lower Portal Pressure [Phase 2]
Phase 2 trial update on serelaxin for lowering portal pressure in liver cirrhosis and portal hypertension.
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CLINICAL_TRIALS withdrawal · 2018-07-26Clinical Trial Update: A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic Patients
A pilot study investigating peripheral endothelial function in patients with portal hypertension and cirrhosis has been withdrawn from the r…
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FDA approval · 2018-07-23FDA Approved: NADOLOL — Original Application (UNICHEM PHARMACEUTICALS (USA), INC.)
FDA approved Nadolol as an original application from Unichem Pharmaceuticals (USA), Inc., establishing a generic nadolol product.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices. [NA]
This clinical trial compared carvedilol with and without simvastatin in patients with portal hypertension and esophageal varices; the study …
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CLINICAL_TRIALS research · 2018-05-08Clinical Trial Update: Can MRI Evaluate Beta-blocker Response in Portal Hypertension?
A clinical trial update from University of Nottingham explores using MRI to assess beta-blocker response in patients with liver cirrhosis an…
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CLINICAL_TRIALS research · 2018-04-25Clinical Trial Update: Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis [Phase 3]
Phase 3 multicenter randomized trial evaluating rivaroxaban on survival and development of portal hypertension complications in patients wit…
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CLINICAL_TRIALS research · 2018-03-15Clinical Trial Update: TIPS in Fundal Variceal Bleeding (the TFB Study) [NA]
Clinical trial update on the TFB study evaluating transjugular intrahepatic portosystemic shunt (TIPS) for fundal/gastric variceal bleeding …
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Evaluation Of The Portal Pressure By Doppler Ultrasound In Cirrhotic Patients Before And After Simvastatin [Phase 4]
A Phase 4 trial from Tanta University evaluating the effect of simvastatin on portal pressure in cirrhotic patients with portal hypertension…
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CLINICAL_TRIALS research · 2017-10-20Clinical Trial Update: Spleen-ARFI-assisted-Portal-Hypertension-Evaluation-Study (SAPHES) [NA]
An update on the SAPHES study sponsored by the University of Ulm evaluating spleen-ARFI-assisted evaluation of portal hypertension; current …
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CLINICAL_TRIALS research · 2017-09-01Clinical Trial Update: Hypersplenism in Patients With Liver Cirrhosis and Portal Hypertension
A clinical trial update regarding hypersplenism in patients with liver cirrhosis and portal hypertension; the status is unknown and no resul…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal [Phase 4]
Phase 4 clinical trial evaluating non-selective beta-blockers to prevent decompensation in cirrhosis with portal hypertension has completed.
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CLINICAL_TRIALS research · 2017-08-08Clinical Trial Update: Role of RDW as Anon Invasive Index for Predicting Liver Cell Failure and Portal Hypertension in Cirrhotic Patient
This clinical trial investigates whether red blood cell distribution width (RDW) can serve as a noninvasive predictor of liver cell failure …
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CLINICAL_TRIALS research · 2017-07-31Clinical Trial Update: The International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP).
Clinical trial registry update for the International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP), listing conditions includin…
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FDA approval · 2017-07-28FDA Approved: NADOLOL — Original Application (Zydus Pharmaceuticals USA Inc.)
FDA approved Nadolol as a generic drug in an Original Application (ANDA) for Zydus Pharmaceuticals USA Inc.
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CLINICAL_TRIALS research · 2017-06-22Clinical Trial Update: WFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver Cirrhosis
This clinical trial update investigates the biomarker WFA+M2BP for evaluating portal hypertension and clinical outcomes in patients with liv…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: Correlation of Platelets Count With Endoscopic Findings in a Cohort of Egyptian Patients With Liver Cirrhosis
This update reports on a study exploring whether platelet counts correlate with endoscopic findings in Egyptian patients with liver cirrhosi…
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FDA approval · 2017-06-02FDA Approved: NADOLOL — Original Application (Amneal Pharmaceuticals NY LLC)
The FDA approved Amneal's original application for a generic nadolol, a non-selective beta-blocker used to treat hypertension and to prevent…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Prevention of Esophageal Varices by Beta-Adrenergic Blockers [Phase 3]
Phase 3 trial evaluating whether beta-adrenergic blockers can prevent esophageal and gastric varices in patients with liver cirrhosis; the s…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C) [NA]
A completed clinical trial (SPLEEN-C) evaluating transient elastography to measure liver fibrosis and portal hypertension in patients with c…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS
This clinical trial update reports that changes in shear-wave elastography (SWE) after TIPS may help predict prognosis in patients with port…
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CLINICAL_TRIALS research · 2017-02-23Clinical Trial Update: Evaluation of Gastroesophageal Varices by Transnasal Endoscopy.
This clinical trial update discusses evaluating gastroesophageal varices using transnasal endoscopy as a diagnostic approach. The study invo…