Portal Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure [Phase 2]
Phase 2 trial of NCX-1000 in patients with portal hypertension showed preliminary efficacy signals and tolerability after repeated oral dosi…
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension [Phase 2]
Phase 2 study of IDN-6556 (emricasan) in patients with cirrhosis and portal hypertension completed; results were posted in 2016.
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CLINICAL_TRIALS research · 2016-12-05Clinical Trial Update: Doppler Ultrasound Hepatic Vein Waveform as a Non-invasive Tool in the Assessment of Severity of Portal Hypertension [Phase 3]
Phase 3 clinical trial evaluating Doppler ultrasound hepatic vein waveform as a non-invasive tool to assess the severity of portal hypertens…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Evaluation of Probiotics in the Treatment of Portal Hypertension [NA]
The trial update notes the completion of a study evaluating probiotics for portal hypertension in patients with liver cirrhosis, portal hype…
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CLINICAL_TRIALS research · 2016-11-10Clinical Trial Update: 3D Sonographic Measurement of Volumetric Flow in Transjugular Intrahepatic Porto-Systemic Shunts [NA]
The clinical trial update notes completion of a study evaluating 3D sonographic measurement of volumetric blood flow in transjugular intrahe…
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CLINICAL_TRIALS research · 2016-09-08Clinical Trial Update: Correlation of Liver and Spleen Stiffness by RT-2D-SWE and Severity of Portal Hypertension by HVPG
This clinical trial investigates the relationship between liver and spleen stiffness and the severity of portal hypertension in patients wit…
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CLINICAL_TRIALS research · 2016-08-09Clinical Trial Update: Microparticles in Cirrhosis and Portal Hypertension [NA]
This entry provides an update on a clinical trial investigating microparticles in liver cirrhosis and portal hypertension. The study is mark…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension [Phase 2]
Phase 2 trial of cobiprostone in portal hypertension was terminated; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal Hypertension
A completed clinical trial conducted in Egypt examined risk factors for variceal bleeding in patients with non-cirrhotic portal hypertension…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation [Phase 2]
Phase 2 trial evaluating sofosbuvir and ribavirin in adults with chronic hepatitis C and cirrhosis, including patients with portal hypertens…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: TIPS With 8- OR 10-mm Covered Stent for Preventing Variceal Rebleeding [NA]
A completed clinical trial evaluated using 8- or 10-mm covered stents for transjugular intrahepatic portosystemic shunt (TIPS) to prevent va…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension [Phase 2]
Phase 2 exploratory haemodynamic study in patients with compensated cirrhosis and portal hypertension. Results were posted in January 2016.
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices [NA]
A clinical trial comparing Cyanoacrylate+Lipiodol versus Cyanoacrylate+Lauromacrogol for gastric varices has completed.
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FDA approval · 2015-12-18FDA Approved: NADOLOL — Original Application (Cipla USA Inc.)
FDA approved Nadolol from Cipla USA Inc. as an original generic application (ANDA). Nadolol is used for hypertension and to prevent esophage…
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CLINICAL_TRIALS research · 2015-11-11Clinical Trial Update: Percutaneous Transhepatic Intrahepatic Portosystemic Shunt for Treatment of Portal Vein Occlusion With Symptomatic Portal Hypertension After Splenectomy [NA]
This clinical trial update relates to using percutaneous transhepatic intrahepatic portosystemic shunt (TIPS) to treat portal vein occlusion…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis [Phase 4]
This update notes the completion of a Phase 4 clinical trial evaluating taurine's effects on portal hemodynamics in patients with advanced l…
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CLINICAL_TRIALS research · 2015-09-25Clinical Trial Update: Value of Von Willebrand Factor in Portal Hypertension
This clinical trial update investigates whether von Willebrand factor can serve as a biomarker for portal hypertension in patients with live…
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FDA approval · 2015-09-16FDA Approved: NADOLOL — Original Application (Aurobindo Pharma Limited)
FDA approved Nadolol tablets as a generic drug under an Original Application (ANDA 201893) from Aurobindo Pharma Limited. This approval make…
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CLINICAL_TRIALS other · 2015-07-28Clinical Trial Update: Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varices [Phase 3]
A Phase 3 trial is evaluating rifaximin for reducing portal pressure in patients with liver cirrhosis and esophageal varices; the study stat…
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CLINICAL_TRIALS research · 2015-07-21Clinical Trial Update: Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal Vein [NA]
This clinical trial update describes interventional radiology approaches to treat symptomatic portal hypertension in patients with cavernous…
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CLINICAL_TRIALS research · 2015-06-24Clinical Trial Update: 3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt Creation [NA]
An update on a trial evaluating 3D CT-guided creation of a transjugular intrahepatic portosystemic shunt for portal hypertension, with the s…
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CLINICAL_TRIALS research · 2015-04-21Clinical Trial Update: Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients [Phase 2, Phase 3]
This document reports a Phase 2/3 clinical trial evaluating rifaximin in combination with propranolol versus propranolol alone in patients w…
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding [Phase 3]
A Phase 3 clinical trial evaluates whether adding a statin to standard therapy reduces recurrent hemorrhage in patients with cirrhosis and p…
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope [Phase 3]
Phase 3 trial comparing two endoscopic methods to stop hematemesis in patients with portal hypertension; the study has completed.
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Evaluation of Efficacy and Safety of Somatostatin Used as Inflow Modulator in Liver Transplantation. [Phase 1]
A completed Phase 1 clinical trial evaluating somatostatin as an inflow modulator to assess safety and efficacy in liver transplantation for…