Portal Hypertension
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Sign up freeTop drugs studied for this disease
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FDA approval · 2024-07-11FDA Approved: NADOLOL — Supplemental Application (Alembic Pharmaceuticals Limited)
The FDA approved a supplemental application for Nadolol from Alembic Pharmaceuticals Limited, expanding access to this generic beta-blocker.
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension [Phase 2, Phase 3]
Clinical trial update indicates evaluation of alverine for cirrhotic portal hypertension in Phase 2 and Phase 3, with the study currently no…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis [Phase 2, Phase 3]
Alverine is being evaluated in Phase 2 and Phase 3 trials for portal hypertension in patients with liver cirrhosis, and the study is not yet…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease. [Phase 3]
Phase 3 trial update announcing a study to evaluate zinc supplementation for improving prognosis in patients with compensated advanced chron…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Freiburg TIPS Registry
Clinical trial update for Freiburg's TIPS Registry showing ongoing recruitment for a registry study of portal hypertension-related condition…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India
An Indian clinical trial investigating the clinical diagnosis and pathology of porto-sinusoidal vascular disease and related liver condition…
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FDA approval · 2024-03-01FDA Approved: NADOLOL — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Nadolol from Aurobindo Pharma Limited under ANDA201893.
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CLINICAL_TRIALS trial_result · 2023-09-05Clinical Trial Update: Velacur by Sonic Incytes for Portal Hypertension [NA]
Completed clinical trial update for Velacur by Sonic Incytes addressing portal hypertension and chronic advanced liver disease, with results…
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FDA approval · 2023-06-02FDA Approved: NADOLOL — Original Application (Alembic Pharmaceuticals Limited)
FDA approved Nadolol under an Original Application from Alembic Pharmaceuticals Limited, authorizing a generic Nadolol product.
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. [Phase 4]
A Phase 4 clinical trial evaluating beta-blockers vs placebo for primary prevention of esophageal varices in patients with cirrhosis and por…
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CLINICAL_TRIALS trial_result · 2022-08-02Clinical Trial Update: Atorvastatin Use and Portal Hypertension in Patients With Hepatitis B Virus-related Liver Cirrhosis: A Randomized Controlled Trial [Phase 2]
A Phase 2 randomized trial evaluating atorvastatin use in patients with hepatitis B virus-related liver cirrhosis and portal hypertension.
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients [Phase 2]
Phase 2 clinical trial assessing safety and efficacy of Ifetroban for portal hypertension in cirrhotic patients has completed with results p…
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CLINICAL_TRIALS trial_result · 2022-01-14Clinical Trial Update: Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension [Phase 2]
Phase 2 trial of emricasan, an oral caspase inhibitor, in subjects with NASH cirrhosis and severe portal hypertension has completed with res…
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CLINICAL_TRIALS trial_result · 2021-08-26Clinical Trial Update: Anticoagulation Therapy After Splenectomy in Cirrhosis Patient [Phase 1, Phase 2]
A clinical trial evaluating anticoagulation therapy after splenectomy in patients with liver cirrhosis and portal hypertension has completed…
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CLINICAL_TRIALS trial_result · 2021-08-13Clinical Trial Update: Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension [Phase 4]
Phase 4 trial update on noninvasive subharmonic aided pressure estimation for portal hypertension in liver disease.
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis [Phase 2]
Phase 2 trial evaluating GR-MD-02 for safety and efficacy in liver fibrosis with portal hypertension due to NASH cirrhosis has completed wit…
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14
A completed clinical trial update for a companion protocol related to the Methacetin Breath Test in the Conatus protocol; results posted in …
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CLINICAL_TRIALS trial_result · 2020-08-25Clinical Trial Update: Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosis [Phase 4]
A Phase 4 clinical trial evaluating spironolactone for fibrosis progression in portal hypertension associated with cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: A Physical Activity Program in End-state Liver Disease [NA]
A completed clinical trial evaluating a physical activity program for patients with end-stage liver disease, including those awaiting liver …
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CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Hemodynamic Profile of Terlipressin and Octreotide in Patients With Cirrhosis and Portal Hypertension. A Randomised, Single Blinded Clinical Trial. [Phase 4]
A phase 4 randomized, single-blinded trial assessing the hemodynamic profile of terlipressin and octreotide in patients with liver cirrhosis…
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CLINICAL_TRIALS other · 2020-02-25Clinical Trial Update: Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPS [Phase 4]
Clinical trial update for a Phase 4 study on early precise diagnosis and intervention of CPT using a noninvasive 3D-vHPS in patients with po…
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: Treatment of Moderate and Severe Cirrhotic Portal Hypertension Due to HBV With Fuzheng Huayu and Entecavir [Phase 4]
A Phase 4 clinical trial evaluating Fuzheng Huayu in combination with Entecavir for treatment of portal hypertension due to hepatitis B viru…
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir [Phase 4]
Phase 4 trial update investigating Fuzheng Huayu plus Entecavir for low-grade cirrhotic portal hypertension due to hepatitis B virus.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver Stiffness [NA]
A terminated clinical trial evaluating transjugular intrahepatic portosystemic shunts (TIPS) and their impact on liver stiffness.
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CLINICAL_TRIALS trial_result · 2019-09-27Clinical Trial Update: Somatostatin in Living Donor Liver Transplantation [Phase 4]
Clinical trial update for somatostatin in living donor liver transplantation (Phase 4) with unknown status.