Polycythemia Vera
📧 Sign up to get email alerts when something new happens for Polycythemia Vera.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC Interval [Phase 1]
Phase 1 trial assessing placebo-corrected QT/QTc effects of ITF2357 (Givinostat) at therapeutic and supratherapeutic doses alongside moxiflo…
-
CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: Myeloproliferative Neoplasms: an In-depth Case-control Study
A completed clinical trial examining myeloproliferative neoplasms with results posted; focuses on Polycythemia Vera, Essential Thrombocythem…
-
CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: Dual Vaccine Trial in Myeloproliferative Neoplasms [Phase 1, Phase 2]
A dual vaccine trial in myeloproliferative neoplasms completed Phase 1/2 testing for polycythemia vera and essential thrombocythemia.
-
CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating LCL161 in patients with various forms of myelofibrosis has completed with results posted in 2023.
-
CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies [Phase 2]
Phase 2 clinical trial update on shorter course tacrolimus after non-myeloablative conditioning with related donor PBSCT and high-dose postt…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2022-04-27Clinical Trial Update: A Study of Low Dose Interferon Alpha Versus Hydroxyurea in Treatment of Chronic Myeloid Neoplasms [Phase 3]
A Phase 3 trial comparing low-dose interferon alpha with hydroxyurea in chronic myeloid neoplasms has completed.
-
CLINICAL_TRIALS trial_result · 2022-01-05Clinical Trial Update: A Phase 2 Study of RO7490677 In Participants With Myelofibrosis [Phase 2]
Phase 2 clinical trial update for RO7490677 in myeloproliferative neoplasms has completed; results posted in 2022.
-
CLINICAL_TRIALS trial_result · 2022-01-04Clinical Trial Update: Therapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and Mastocytosis With Imatinib Mesylate [NA]
Clinical trial update of imatinib mesylate for various myeloproliferative and related neoplasms including CMML, CML, polycythemia vera, hype…
-
CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. [Phase 3]
Phase 3 trial comparing ruxolitinib versus best available therapy in patients with polycythemia vera resistant or intolerant to hydroxyurea;…
-
CLINICAL_TRIALS trial_result · 2021-06-21Clinical Trial Update: PD-1 Inhibition in Advanced Myeloproliferative Neoplasms [Phase 2]
Phase 2 trial assessing PD-1 inhibition in advanced myeloproliferative neoplasms has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: AOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study. [Phase 3]
Phase 3 trial comparing AOP2014 to BAT in Polycythemia Vera patients who previously participated in PROUD-PV has completed.
-
CLINICAL_TRIALS trial_result · 2021-05-27Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera [Phase 2]
Phase 2 trial evaluating idasanutlin monotherapy in hydroxyurea-resistant/intolerant polycythemia vera; study terminated with results posted…
-
CLINICAL_TRIALS trial_result · 2021-02-05Clinical Trial Update: Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia [Phase 2]
Phase 2 long-term safety and efficacy update for momelotinib in various myelofibrosis subtypes; study completed with results posted in 2021.
-
CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: KRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera [Phase 2]
Phase 2 trial update comparing KRT-232 to ruxolitinib in phlebotomy-dependent polycythemia vera is underway but status is unknown.
-
CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Phase IIA Study of the HDAC Inhibitor ITF2357 in Patients With JAK-2 V617F Positive Chronic Myeloproliferative Diseases [Phase 2]
Phase IIa study of HDAC inhibitor ITF2357 in JAK-2 V617F positive myeloproliferative diseases has completed with posted results.
-
CLINICAL_TRIALS trial_result · 2019-10-31Clinical Trial Update: Phase II Study of GIVINOSTAT (ITF2357) in Combination With Hydroxyurea in Polycythemia Vera [Phase 2]
Phase II study of GIVINOSTAT (ITF2357) in combination with hydroxyurea in polycythemia vera has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: A Two-part Study to Assess the Safety and Preliminary Efficacy of Givinostat in Patients With Polycythemia Vera [Phase 1, Phase 2]
A two-part Phase 1/2 trial evaluating the safety and preliminary efficacy of givinostat in patients with polycythemia vera has completed wit…
-
CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: Pomalidomide for Myelofibrosis Patients [Phase 2]
Phase 2 clinical trial evaluating pomalidomide in myelofibrosis patients has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation [Phase 2]
Phase 2 clinical trial update evaluating a sympathicomimetic agonist in patients with myeloproliferative neoplasms carrying JAK2 mutations, …
-
CLINICAL_TRIALS trial_result · 2019-05-06Clinical Trial Update: Dasatinib as Therapy for Myeloproliferative Disorders (MPDs) [Phase 2]
Phase 2 trial evaluating dasatinib for myeloproliferative disorders; the study has completed and results were posted in 2019.
-
CLINICAL_TRIALS trial_result · 2019-04-02Clinical Trial Update: Expanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resistant or Intolerant and for Whom no Treatment Alternatives Was Available. [Phase 3]
Phase 3 trial evaluating expanded treatment protocol of ruxolitinib in polycythemia vera patients resistant or intolerant to hydroxyurea wit…
-
CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET) [Phase 3]
A Phase 3 randomized trial comparing pegylated interferon alfa-2a to hydroxyurea in high-risk polycythemia vera and high-risk essential thro…
-
CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: A Study in Myeloproliferative Disorders [Phase 1]
Phase 1 study in myeloproliferative neoplasms has completed, evaluating patients with essential thrombocythemia, polycythemia vera, and prim…
-
CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Trial of Erlotinib in Patients With JAK-2 V617F Positive Polycythemia Vera [Phase 2]
A Phase 2 trial of erlotinib in patients with JAK-2 V617F positive polycythemia vera has been terminated, with results posted in 2018.
-
CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera [Phase 1, Phase 2]
A safety study evaluating pegylated interferon alpha-2b in Polycythemia Vera has completed Phase 1 and Phase 2 trials.