Polycythemia Vera
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-04-24EMA Authorised: Besremi (ropeginterferon alfa-2b) — AOP Orphan Pharmaceuticals GmbH
The EMA authorised Besremi (ropeginterferon alfa-2b) for the treatment of polycythemia vera; decision date 24 April 2026.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms [Phase 1, Phase 2]
The Phase 1/2 study evaluating the combination of ruxolitinib and CPX-351 in advanced phase myeloproliferative neoplasms was terminated, wit…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors [Phase 4]
A Phase 4 clinical trial assessing hydroxyurea resistance in adults with polycythemia vera using PV-AIM predictors has been terminated.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX) [Phase 2]
This Phase 2 trial from the University of Manitoba is evaluating antibiotic prophylaxis in patients with myelodysplastic syndrome and acute …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms [Phase 1]
This clinical trial update announces a Phase 1 study of JNJ-88549968 for CALR-mutated myeloproliferative neoplasms and indicates the trial i…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study of ZE74-0282 for Patients With JAK2 V617F Positive Blood Cancers [Phase 1]
ZE74-0282 is the subject of a Phase 1 trial for JAK2 V617F-positive blood cancers, including polycythemia vera and myelofibrosis, and the st…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs) [Phase 2]
A Phase 2 randomized trial evaluating ASTX727 with or without iadademstat in advanced myeloproliferative neoplasms, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid Leukemia [NA]
The ENERGIA study tests a personalized exercise program to reduce fatigue in patients with myeloproliferative neoplasms and chronic myeloid …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017) [Phase 3]
Phase 3 study of bomedemstat (MK-3543-017) sponsored by Merck is currently recruiting to evaluate safety and efficacy in essential thrombocy…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
This Phase 2 trial update reports completion of a study evaluating the combination of ruxolitinib phosphate and azacitidine in patients with…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms [Phase 1]
Phase 1 study of PRT12396 in select myeloproliferative neoplasms is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial evaluating curcumin to improve inflammation and symptoms in patients with clonal cytopenia of undetermined significan…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera [Phase 3]
Phase 3 clinical trial comparing givinostat to hydroxyurea in patients with polycythemia vera is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms [Phase 3]
Phase 3 clinical trial AVAJAK compares apixaban or rivaroxaban with aspirin for primary prevention of thromboembolic events in patients with…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms [Phase 2]
A Phase 2 clinical trial evaluating decitabine in combination with JAK inhibitors (ruxolitinib, fedratinib, or pacritinib) for accelerated o…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: CINC424A2X01B Rollover Protocol [Phase 4]
Phase 4 rollover protocol for CINC424A2X01B is active but not recruiting, spanning Primary Myelofibrosis, Polycythemia Vera, Graft-versus-ho…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms [Phase 1, Phase 2]
This clinical trial aims to identify the optimal dose of N-acetylcysteine in patients with myeloproliferative neoplasms. It spans Phase 1/2 …
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Identification of Factors Associated With Treatment Response in Patients With Polycythemia Vera, Essential Thrombocythemia, and Pre-myelofibrosis.
A clinical trial update focused on identifying factors associated with treatment response in patients with polycythemia vera, essential thro…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Phase IIa Study on Flonoltinib Maleate Tablets in the Treatment of Patients With Polycythemia Vera [Phase 2]
Phase IIa study of Flonoltinib Maleate Tablets for polycythemia vera is currently recruiting. The sponsor is Chengdu Zenitar Biomedical Tech…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV) [Phase 2]
Phase 2 open-label study of DISC-3405 in participants with polycythemia vera is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Clinical Study of Gecacitinib Combined With Pegylated Interferon in Patients With PV [NA]
Clinical study evaluating Gecacitinib combined with Pegylated Interferon in Polycythemia Vera; recruitment has not yet begun.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV) [Phase 3]
This clinical trial update describes a Phase 3 study of Sapablursen evaluating safety and efficacy in participants with Polycythemia vera, w…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)
This entry describes the MPN PROGRESSion Registry, an observational study to track symptoms, treatments, and disease progression in people w…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia Vera [Phase 2]
Phase 2 clinical trial update for Sapablursen (formerly ISIS 702843, IONIS-TMPRSS6-LRx) in polycythemia vera; the study is currently active …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Potential Biological and Physiological Determinants for Exercice in Patients With Polycythemia Vera [NA]
A clinical trial update from Hospices Civils de Lyon describes a study investigating biological and physiological determinants of exercise i…