Polycythemia Vera
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms [Phase 1, Phase 2]
The Phase 1/2 study evaluating the combination of ruxolitinib and CPX-351 in advanced phase myeloproliferative neoplasms was terminated, wit…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors [Phase 4]
A Phase 4 clinical trial assessing hydroxyurea resistance in adults with polycythemia vera using PV-AIM predictors has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
This Phase 2 trial update reports completion of a study evaluating the combination of ruxolitinib phosphate and azacitidine in patients with…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial evaluating curcumin to improve inflammation and symptoms in patients with clonal cytopenia of undetermined significan…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: CINC424A2X01B Rollover Protocol [Phase 4]
Phase 4 rollover protocol for CINC424A2X01B is active but not recruiting, spanning Primary Myelofibrosis, Polycythemia Vera, Graft-versus-ho…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Phase IIa Study on Flonoltinib Maleate Tablets in the Treatment of Patients With Polycythemia Vera [Phase 2]
Phase IIa study of Flonoltinib Maleate Tablets for polycythemia vera is currently recruiting. The sponsor is Chengdu Zenitar Biomedical Tech…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia Vera [Phase 2]
Phase 2 clinical trial update for Sapablursen (formerly ISIS 702843, IONIS-TMPRSS6-LRx) in polycythemia vera; the study is currently active …
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: CO-Rebreathing in Comparison to Isotopic Red Cell Volume Determination in the Diagnosis of Primitive and Secondary Polycythemia [NA]
The study compares CO-rebreathing with isotopic red cell volume measurement for diagnosing primitive and secondary polycythemia; the trial s…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Efficacy and Safety of P1101 in Polycythemia Vera Patients for Whom the Standard of Treatment is Difficult to Apply [Phase 2]
Phase 2 trial evaluating the efficacy and safety of P1101 in polycythemia vera patients with difficult-to-treat standard therapies. Results …
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE) [Phase 2]
Phase 2 REVIVE trial evaluating a hepcidin mimetic in polycythemia vera has completed.
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Study to Evaluate the Long-term Safety of Rusfertide (PTG-300) in Subjects With Polycythemia Vera [Phase 3]
A phase 3 long-term safety study of Rusfertide (PTG-300) in polycythemia vera is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: A Study of Bomedemstat (MK-3543) in Participants With Polycythemia Vera (MK-3543-004) [Phase 2]
The Phase 2 MK-3543-004 trial evaluating Bomedemstat in polycythemia vera has completed.
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia [Phase 2]
Phase 2 clinical trial (Ruxo-BEAT) evaluating ruxolitinib in high-risk polycythemia vera or high-risk essential thrombocythemia; the study i…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders [Phase 1]
Phase 1 study of Veliparib with Topotecan, with or without Carboplatin, in relapsed or refractory acute leukemias, high-risk myelodysplastic…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Study With SAR302503 in Patients With Polycythemia Vera or Essential Thrombocythemia [Phase 2]
Phase 2 clinical trial update from Bristol-Myers Squibb evaluating SAR302503 in polycythemia vera or essential thrombocythemia; the study st…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: A Study to Evaluate P1101 in Japanese PV Patients [Phase 3]
Phase 3 study evaluating P1101 in Japanese patients with Polycythemia Vera has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: The Benefit/Risk Profile of AOP2014 in Low-risk Patients With PV [Phase 2]
Phase 2 trial update reporting results for AOP2014 in low-risk polycythemia vera patients, detailing its benefit/risk profile.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213) [Phase 2]
Phase 2 LIMBER-213 evaluated the safety, tolerability, and efficacy of Itacitinib immediate-release tablets in adults with primary or second…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Clinical and Laboratory Characteristics of Polycythemia Vera
This completed clinical trial investigated the clinical and laboratory characteristics of polycythemia vera, reported by IRCCS Azienda Osped…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV [Phase 2]
Phase 2 trial evaluating the combination of pegylated interferon α-2b with ruxolitinib for hydroxyurea-resistant or intolerant polycythemia …
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea [Phase 1]
This Phase 1 trial evaluated the combination of TGR-1202 and ruxolitinib in patients with myelofibrosis and polycythemia vera who are resist…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients [Phase 2]
Phase 2 feasibility study evaluating apixaban for thromboprophylaxis in patients with JAK2-positive myeloproliferative neoplasms (including …
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: A Prospective, Non-interventional Study of JAKAVI® (Ruxolitinib) Treatment in Patients With Polycythemia Vera
A completed prospective, non-interventional study evaluating JAKAVI (ruxolitinib) for Polycythemia Vera. Sponsor: Novartis Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 trial update evaluating topotecan hydrochloride and carboplatin with or without veliparib for advanced myeloproliferative disorders …
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CLINICAL_TRIALS trial_result · 2024-03-18Clinical Trial Update: PTG-300 in Patients With Polycythemia Vera and Elevated Hematocrit [Phase 2]
Phase 2 clinical trial update for PTG-300 in polycythemia vera with elevated hematocrit has completed.