Clinical Trial Update: A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs) [Phase 2]

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Summary

A Phase 2 randomized trial evaluating ASTX727 with or without iadademstat in advanced myeloproliferative neoplasms, currently recruiting.

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Diseases / indications

• Accelerated-phase Myeloproliferative Neoplasm
• Blast-phase Myeloproliferative Neoplasm
• Essential Thrombocythemia
• Myelodysplastic Myeloproliferative Neoplasm
• Myelofibrosis
• Myeloproliferative Neoplasm Not Otherwise Specified
• Polycythemia Vera

Drugs mentioned

• ASTX727 (cedazuridine/decitabine)
• Iadademstat (iadademstat)

Snippet

Sponsor: National Cancer Institute (NCI) | Conditions: Accelerated Phase Myeloproliferative Neoplasm, Blast Phase Myeloproliferative Neoplasm | Phase 2 | Status: RECRUITING