Pleural Empyema
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic [NA]
A completed clinical trial from the National University of Malaysia comparing pleural irrigation with normal saline to intrapleural fibrinol…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas [NA]
This entry notes an ongoing clinical trial evaluating regular chest drain flushing for complicated parapneumonic effusions and empyemas, cur…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Fungal Empyema Thoracis [NA]
A clinical trial update shows a study on fungal empyema thoracis is currently recruiting, sponsored by the University of Health Sciences Lah…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Infections [NA]
A completed pharmacokinetic study evaluating how amoxicillin and clavulanic acid distribute into pleural fluid in patients with pleural infe…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: VATS Surgery Compared to Drainage in the Treatment of Pleural Empyema [NA]
Clinical trial is recruiting to compare video-assisted thoracoscopic surgery (VATS) versus drainage for pleural empyema.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: The Role of Decortication in Complex Empyema Cases: Multidrug Resistance and Tuberculosis at the Forefront
A completed clinical trial evaluates decortication in complex pleural empyema, with focus on multidrug-resistant infections and tuberculosis…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Pleural Tissue Culture Versus Pleural Fluid Culture in Infected Effusion [NA]
This ClinicalTrials.gov update describes an ongoing study comparing pleural tissue culture to pleural fluid culture for infected pleural eff…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Comparison of Lung Expansion After Uniportal and Multiportal Video Assisted Thoracic Surgery for Stage II Post Pneumonic Bacterial Empyema Thoracis [NA]
A completed clinical trial comparing uniportal and multiportal video-assisted thoracic surgery for stage II post-pneumonic bacterial empyema…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Evaluating the Efficacy and Safety of Saline Irrigation as an Add-On Therapy for Retained Pleural Infections [LYTICS +] [Phase 2]
Phase 2 clinical trial assessing saline irrigation as an add-on treatment for retained pleural infections; study is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Evaluation of Efficacy and Safety Parameters of Different Antibiotics Regimens for Management of Empyema [NA]
A clinical trial is evaluating the efficacy and safety of different antibiotic regimens for the management of pleural empyema. The study is …
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Complicated Pneumonia (CP) in Children in South-East Europe
A clinical trial in Southeastern Europe is currently recruiting to study complicated pneumonia in children. The study includes necrotizing p…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: The Oxford Pleural Infection Endotyping Study
The Oxford Pleural Infection Endotyping Study has completed. The study investigates endotypes in pleural infection and related pleural disea…
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CLINICAL_TRIALS trial_result · 2021-10-14Clinical Trial Update: A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia [Phase 4]
Phase 4 trial comparing regional anesthesia during thoracoscopy to conventional general anesthesia in pleural disease settings; status curre…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) [Phase 3]
Phase 3 trial evaluating intrapleural DNase and tissue plasminogen activator for pediatric empyema has completed with results posted.
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CLINICAL_TRIALS research · 2019-02-22Clinical Trial Update: Chest Wall Motion Analysis in Disease
This completed clinical trial examines chest wall motion analysis across several diseases, including mesothelioma, lung cancer, COPD, cystic…
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CLINICAL_TRIALS research · 2018-07-05Clinical Trial Update: Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children [Phase 3]
Phase 3 clinical trial comparing intrapleural urokinase to video-assisted thoracoscopic surgery for parapneumonic pleural effusion in childr…
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Procalcitonin in Pleural Pleuritis
A completed clinical trial evaluating procalcitonin in pleural pleuritis and pleural empyema.
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CLINICAL_TRIALS trial_result · 2016-05-24Clinical Trial Update: Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema [Phase 3]
A Phase 3 trial comparing early medical thoracoscopy to chest tube drainage for complicated parapneumonic effusion and pleural empyema was t…
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CLINICAL_TRIALS trial_result · 2011-07-18Clinical Trial Update: Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema [Phase 4]
A Phase 4 clinical trial comparing intrapleural alteplase to urokinase for complicated parapneumonic pleural effusion and empyema has comple…
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CLINICAL_TRIALS trial_result · 2008-05-12Clinical Trial Update: Dornase Alfa and Urokinase for Kids With Pleural Empyema [Phase 2, Phase 3]
A clinical trial update on using dornase alfa and urokinase in children with pleural empyema, conducted in Phase 2 and Phase 3 stages; the c…