Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-09Clinical Trial Update: Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenya [Phase 3]
Phase 3 trial evaluating community-based mass screening and treatment for falciparum malaria in Western Kenya has completed.
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Safety and Efficacy Dose of Artesunate Used in Combination With LAPDAP Treatment of Uncomplicated Falciparum Malaria [Phase 2]
This Phase 2 trial reports safety and efficacy data for artesunate used in combination with LAPDAP to treat uncomplicated Plasmodium falcipa…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa [Phase 3]
Phase 3 clinical trial evaluating susceptibility testing of antimalarial drugs to improve management of drug-resistant malaria in Sub-Sahara…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria [Phase 2]
Completed Phase 2 pharmacokinetic/pharmacodynamic study of Eurartesim dispersible formulation in infants with Plasmodium falciparum malaria.
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax [Phase 2]
A Phase IIa study of the malaria candidate DSM265 for Plasmodium falciparum and Plasmodium vivax malaria has completed.
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults [Phase 1]
Phase 1 dose-escalation, randomized trial assessing safety, immunogenicity and efficacy of the PfSPZ Vaccine in Tanzanian adults; the study …
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinean Adults [Phase 1]
Phase 1 study evaluating the safety and immunogenicity of direct venous inoculation of a radiation-attenuated PfSPZ vaccine in Equatoguinean…
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria Transmission [Phase 3]
Phase 3 trial evaluating dihydroartemisinin-piperaquine with low-dose primaquine to reduce malaria transmission has completed.
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria [Phase 4]
Phase 4 clinical trial assessing in vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated Plasmodium falcipa…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated the safety and efficacy of concomitant administration of ChAd63/MVA ME-TRAP with RTS,S malaria vaccine…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5 [Phase 1]
Phase 1 trial assessing safety and immunogenicity of two malaria vaccine candidates (ChAd63 RH5 alone and with MVA RH5) targeting Plasmodium…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, Indonesia [Phase 4]
Phase 4 clinical trial update evaluating artemisinin-based combination therapy for Plasmodium falciparum malaria conducted in North Sumatera…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Low Dose Primaquine for Clearance of Gametocytes [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating low-dose primaquine to clear gametocytes in malaria has completed.
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso [Phase 4]
Phase 4 trial comparing artemether-lumefantrine (AL) with artesunate–amodiaquine (ASAQ) for treating uncomplicated Plasmodium falciparum mal…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update assessing the efficacy, safety, and pharmacokinetics of an artemether-lumefantrine dispersible table…
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CLINICAL_TRIALS research · 2015-06-15Clinical Trial Update: Evaluation of Fosmidomycin and Piperaquine in the Treatment of Acute Falciparum Malaria [Phase 2]
A Phase 2 trial evaluating fosmidomycin in combination with piperaquine for acute uncomplicated Plasmodium falciparum malaria is being condu…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Tracking Resistance to Artemisinin (TRAC) [Phase 4]
The Phase 4 TRAC trial tracking resistance to artemisinin in Plasmodium falciparum malaria has been completed.
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CLINICAL_TRIALS trial_result · 2015-04-23Clinical Trial Update: Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge [Phase 1]
A Phase 1 trial evaluating how Plasmodium falciparum exposure and sickle cell trait influence infection rates and kinetics after IV administ…
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: A Study of Safety and Immunogenicity of a Malaria Vaccine Candidate [Phase 1]
A Phase 1 study evaluating safety and immunogenicity of a malaria vaccine candidate has completed. The sponsor reported completion of a Phas…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa [Phase 3]
Phase 3 trial evaluating the combination of azithromycin and chloroquine for parasitological clearance and pharmacokinetics in asymptomatic …
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CLINICAL_TRIALS trial_result · 2015-01-09Clinical Trial Update: A Phase I/IIa Study of the Safety, Immunogenicity and Efficacy of FMP2.1/AS01B, an Asexual Blood-Stage Vaccine for Plasmodium Falciparum Malaria [Phase 1, Phase 2]
This Phase 1/2a study evaluated the safety, immunogenicity, and efficacy of the malaria vaccine FMP2.1/AS01B for Plasmodium falciparum malar…
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects [Phase 1]
A Phase 1 trial evaluated the safety, tolerability and pharmacokinetics of OZ439 in healthy male and female volunteers.
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Efficacy and Safety of a Single Low-dose Primaquine for the Clearance of Gametocytes [Phase 4]
This Phase 4 trial evaluates the efficacy and safety of a single low-dose primaquine for clearance of gametocytes in Plasmodium falciparum m…
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection [Phase 2]
Phase 2 clinical trial evaluating the efficacy, tolerability, and pharmacokinetics of OZ439 in adults with acute, uncomplicated malaria due …
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S [Phase 1, Phase 2]
Safety and efficacy study of ChAd63/MVA METRAP combined with RTS,S in malaria has completed Phase 1 and Phase 2.