Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Artemisinin Partial Resistance in Ethiopian Plasmodium Falciparum: A Multisite Clinical, Molecular and In Vitro Study [NA]
Completed multisite study evaluating artemisinin partial resistance in Plasmodium falciparum from Ethiopia, including clinical, molecular, a…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants [Phase 1]
A Phase 1 study to assess the safety of GSK4024484 in healthy adults is actively recruiting, sponsored by GlaxoSmithKline, for Plasmodium fa…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: R21/MM Dosing, Presentations, and Preservatives [Phase 4]
This clinical trial update covers Phase 4 dosing for the R21/MM malaria vaccine, along with recent presentations and preservatives used in t…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Assessing the Safety, Immunogenicity and Ex-vivo Efficacy of Two Candidate Malaria Transmission Blocking Vaccines, Pfs25-IMX313 and Pfs45/48 Administered Alone and in Combination, in Matrix-M Adjuvant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety, immunogenicity, and ex-vivo efficacy of two candidate malaria transmission-blocking vaccines…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating safety, pharmacokinetics, and the transmission-reducing activity of the monoclonal antibody TB31F in …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Mass Vaccine and Drug Administration, Bangladesh [Phase 4]
This is an update on a Phase 4 clinical trial in Bangladesh evaluating mass vaccine and drug administration for Plasmodium falciparum malari…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adults [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of a recombinant AMA1-DiCo malaria vaccine formulated with GLA-SE and Alhydrogel in m…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Safety and Immunogenicity of SUM-101 Malaria Vaccine in Children and Infants Living in Burkina Faso [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of SUM-101 malaria vaccine in children and infants in Burkina Faso.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Participants With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
A Phase 2 platform study evaluating the efficacy and safety of anti-malarial agents in participants with uncomplicated Plasmodium falciparum…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants [Phase 1]
Phase 1 single-ascending-dose trial assessing safety, tolerability, and pharmacokinetics of MMV371 LAI in healthy participants; study comple…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1) [Phase 2]
Phase IIa proof-of-concept study CAPTURE 1 evaluating the fixed-dose combination M5717-Pyronaridine in adults and adolescents with acute unc…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria
This clinical trial update reports the completion and results of a comparative study on thrombocytopenia in Plasmodium vivax malaria versus …
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Permethrin-treated Baby-wraps for the Prevention of Malaria in Children [NA]
Completed clinical trial evaluating whether permethrin-treated baby wraps can prevent malaria in children.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Faso [Phase 1, Phase 2]
A completed Phase 1/2 trial in 5-17 month old children in Nanoro, Burkina Faso evaluated the safety, immunogenicity, and efficacy of the R21…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults [Phase 2]
A Phase 2 clinical trial evaluating the safety and immunogenicity of the R21/Matrix-M malaria vaccine in healthy Thai adults has completed. …
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Efficacy of Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Children Under 12 Years at Four Sentinel Sites in Mozambique [NA]
This completed clinical trial evaluates the efficacy of artemether-lumefantrine for treating uncomplicated Plasmodium falciparum malaria in …
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Targeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia [Phase 3]
PATH-sponsored Phase 3 clinical trial in Ethiopia evaluating targeted antimalarial drug administration for seasonal migrant populations in t…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK [EARLY_Phase 1]
Early-phase 1 study of the Pfs48/45 malaria vaccine candidate with Matrix-M adjuvant in the UK was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy [Phase 4]
A Phase 4 clinical trial in Uganda is assessing transmission of artemisinin-resistant parasites before and after conventional artemisinin-ba…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Safety, Immunogenicity and ex Vivo Efficacy of Pfs25-IMX313/Matrix-M in Healthy Volunteers in Bagamoyo, Tanzania. [Phase 1]
Phase 1 trial evaluating safety, immunogenicity, and ex vivo efficacy of the Pfs25-IMX313/Matrix-M malaria vaccine in healthy volunteers in …
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Malaria Vaccine Pilot Evaluation
A pilot evaluation of a malaria vaccine has completed, reporting feasibility and safety outcomes in relation to Plasmodium falciparum malari…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI [Phase 1]
Phase 1 trial of PfSPZ Vaccine in healthy adults to evaluate safety, tolerability, and efficacy against heterologous controlled human malari…
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria [Phase 2, Phase 3]
Phase 2/3 trial evaluating pharmacokinetics, safety, tolerability, and efficacy of a new artemether-lumefantrine dispersible tablet in infan…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali [Phase 2]
A Phase 2 trial in Mali evaluating the gametocytocidal and transmission-blocking effects of ASAQ and ALAQ with or without primaquine in falc…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carriers [Phase 1]
Phase 1 clinical trial evaluating safety, tolerability, and pharmacokinetics of different orally administered regimens of the ZY19489-Ferroq…