Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Malaria Transmission and Immunity in Highland Kenya
This clinical trial update documents the completed status of a study on malaria transmission and immunity in highland Kenya. The sponsor is …
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Plasmodium Resistance in A. Gambiae
Completed clinical trial update examining Plasmodium resistance in Anopheles gambiae in the context of malaria (Plasmodium falciparum).
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CLINICAL_TRIALS withdrawal · 2019-01-30Clinical Trial Update: SP Resistance and Falciparum Malaria Transmission [Phase 3]
Phase 3 trial evaluating sulfadoxine-pyrimethamine resistance and falciparum malaria transmission has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-01-23Clinical Trial Update: CS DNA MVA Trial in Mampong, Ghana [Phase 1]
Phase 1 CS DNA MVA malaria vaccine trial in Mampong, Ghana was withdrawn.
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CLINICAL_TRIALS trial_result · 2018-12-12Clinical Trial Update: Efficacy and Safety of Artesunate + Amodiaquine With SLD of Primaquine for Treatment of Falciparum Malaria in Zanzibar [Phase 4]
Phase 4 clinical trial updating the efficacy and safety of artesunate plus amodiaquine with primaquine as single low dose in treating Plasmo…
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005 [Phase 4]
Phase 4 trial comparing artesunate + amodiaquine versus artemether-lumefantrine for Plasmodium falciparum malaria conducted in Zanzibar; com…
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar [Phase 4]
Phase 4 trial comparing tolerability and efficacy of artemether-lumefantrine versus artesunate + amodiaquine for Plasmodium falciparum malar…
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America [Phase 1, Phase 2]
Phase I/II clinical trial update for a malaria vaccine in adults in the United States (completed; results posted).
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America [Phase 1, Phase 2]
A Phase 1/2 clinical trial of a malaria vaccine conducted in adults in the United States has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: Triple Antimalarial Combination to Accelerate the Parasite Clearance and to Prevent the Selection of Resistant Parasites [Phase 2]
Phase 2 clinical trial evaluating a triple antimalarial combination to speed parasite clearance and reduce emergence of resistance in drug-r…
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CLINICAL_TRIALS withdrawal · 2018-07-05Clinical Trial Update: Phase 1 Study of the Safety and Immunogenicity of a Malaria Transmission-blocking Pfs25-Pfs25 Conjugate Vaccine [Phase 1]
A Phase 1 trial assessing the safety and immunogenicity of a Pfs25-Pfs25 conjugate malaria vaccine has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Artemisinin-resistant Malaria in Cambodia
This clinical trial update reports on a completed study investigating artemisinin-resistant Plasmodium falciparum malaria in Cambodia.
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO [Phase 4]
Phase 4 clinical trial evaluating ARCO for Plasmodium falciparum malaria reports safety, tolerability, pharmacokinetics and efficacy data; t…
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FDA label_change · 2018-01-08FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for COARTEM (artemether and lumefantrine) submitted by Novartis Pharmaceuticals Corporation. The app…
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: Phase 1 Trial of a Malaria Vaccine in Young Kenyan Children [Phase 1]
Phase 1 trial of a malaria vaccine conducted in young Kenyan children has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, Mali [Phase 1]
Phase 1 trial update for the malaria vaccine FMP2.1/AS02A in malaria-experienced adults in Mali; the study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: PpPfs25/ISA51 and ScPvs25/ISA51 Vaccines for Malaria [Phase 1]
Phase 1 clinical trial update reporting completion of a study evaluating two malaria vaccines, PpPfs25/ISA51 and ScPvs25/ISA51, for Plasmodi…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Experimental Vaccine for Plasmodium Falciparum Malaria [Phase 1]
This update notes the completion of a Phase 1 clinical trial of an experimental vaccine targeting Plasmodium falciparum malaria, sponsored b…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Experimental Vaccine for Malaria in Adults in Mali [Phase 1]
A Phase 1 trial of an experimental malaria vaccine conducted in adults in Mali has completed, sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis [Phase 1]
Phase 1 trial evaluating immunity conferred by immunization with cryopreserved Plasmodium falciparum sporozoites under chloroquine prophylax…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis [Phase 1]
Phase 1 trial assessing safety and protective efficacy of intravenous immunization with cryopreserved Plasmodium falciparum sporozoites unde…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection [Phase 2]
Phase 2 study evaluating the safety and protective efficacy of Bacillus Calmette-Guérin (BCG) vaccination against controlled human malaria i…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: An Evaluation of Weekly Tafenoquine [Phase 2]
A Phase 2 trial evaluated weekly tafenoquine for falciparum parasitaemia (malaria) with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Efficacy and Safety of Dihydroartemisinin-piperaquine (DHP) for the Treatment of Uncomplicated Malaria
A completed trial evaluating the efficacy and safety of dihydroartemisinin-piperaquine for treating uncomplicated malaria caused by Plasmodi…
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria. [Phase 2, Phase 3]
Phase II/Phase III efficacy study of Artefenomel and Piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria has…