Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Short Course Radical Cure of P. Vivax Malaria in Nepal [Phase 4]
This clinical trial update reports the completion of a Phase 4 study in Nepal evaluating a short-course radical cure for Plasmodium vivax ma…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities [NA]
A completed clinical trial evaluating mass drug administration with dihydroartemisinin-piperaquine and a single low-dose primaquine to accel…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia [Phase 4]
Phase 4 trial update evaluating the efficacy of artesunate-amodiaquine and artemether-lumefantrine for treating uncomplicated Plasmodium fal…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in Mali [Phase 1]
A Phase 1 study of the malaria transmission-blocking vaccine Pfs230D1-EPA/Matrix-M in adults in Mali has completed and results have been pos…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali [Phase 2]
Phase 2 trial in Mali evaluating the safety and efficacy of CIS43LS, an anti-malaria monoclonal antibody, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: MSP3-CRM-Vac4All/ Alhydrogel® Vaccine [Phase 1, Phase 2]
Phase 1/2 clinical trial update for the MSP3-CRM-Vac4All/Alhydrogel vaccine addressing malaria caused by Plasmodium falciparum.
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CLINICAL_TRIALS trial_result · 2023-03-30Clinical Trial Update: Additional Screening With Sensitives RDTs and Malaria [Phase 3]
Phase 3 trial update exploring additional screening with Sensitives rapid diagnostic tests for Plasmodium falciparum malaria and malaria dia…
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31F [Phase 1]
Phase 1 trial update reporting safety, tolerability, pharmacokinetics, and pharmacodynamics of TB31F for malaria caused by Plasmodium falcip…
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CLINICAL_TRIALS trial_result · 2023-01-13Clinical Trial Update: Safety and Preliminary Protective Efficacy of Genetically Attenuated GA2 Parasites. [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating safety and preliminary protective efficacy of genetically attenuated GA2 parasites for Plasmodium …
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: Safety and Efficacy of NF135 CPS Immunization [NA]
Clinical trial update for NF135 CPS immunization shows termination with posted results, involving malaria falciparum and controlled human ma…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine [Phase 2, Phase 3]
Phase 2/3 trial comparing pyronaridine-artesunate to artemether-lumefantrine for malaria shows efficacy and safety data from completed study…
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CLINICAL_TRIALS trial_result · 2022-01-28Clinical Trial Update: Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) [Phase 3]
Phase 3 trial update on seasonal malaria vaccination (RTS,S/AS01) and seasonal malaria chemoprevention (SP/AQ) completed with results posted…
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CLINICAL_TRIALS trial_result · 2021-12-15Clinical Trial Update: Safety and Protective Efficacy of Pb(PfCS@UIS4) [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and protective efficacy of Pb(PfCS@UIS4); results completed with posted results in 2021.
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+Mefloquine Versus Artemether-lumefantrine in Kenyan Children [Phase 3]
Phase 3 trial comparing arterolane-piperaquine alone, with mefloquine, and artemether-lumefantrine in Kenyan children for treatment of Plasm…
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CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria [Phase 2]
Phase II dose-ranging study of Pyronaridine/Artesunate in adults with Plasmodium falciparum malaria completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1 [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1/Phase 2 results for the NMRC-M3V-Ad-PfCA vaccine targeting Plasmodium falciparum.
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Assessment of the Therapeutic Efficacy and Tolerability of the Artesunate/Amodiaquina Combination and Artemether/Lumefantrine Combination, Treatment of Uncomplicated P. Falciparum Malaria in the Department of Chocó (Colombia) [Phase 4]
Phase 4 clinical trial assessing artesunate/amodiaquine vs artemether/lumefantrine for uncomplicated Plasmodium falciparum malaria with comp…
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: Drug Combinations of Atovaquone-Proguanil (AP) With ACT [Phase 4]
Phase 4 clinical trial update evaluating combinations of atovaquone-proguanil with artemisinin-based combination therapy for drug-resistant …
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Targeted Active Case Detection Among High Risk Populations in Southern Lao Peoples Democratic Republic [Phase 4]
Phase 4 trial update evaluating targeted active case detection in high-risk populations for Plasmodium falciparum malaria in southern Lao PD…
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CLINICAL_TRIALS trial_result · 2020-12-11Clinical Trial Update: Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults. [Phase 2]
Phase 2 trial update assessing safety and immunogenicity of RTS,S/AS02A and RTS,S/AS01B malaria vaccines in malaria-experienced adults.
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria [Phase 1]
Phase 1 trial updates for DSM265 as a chemoprophylaxis against Plasmodium falciparum malaria; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: SJ733 Induced Blood Stage Malaria Challenge Study [Phase 1]
Phase 1 clinical trial update for SJ733 inducing blood-stage malaria, completed with results posted.
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CLINICAL_TRIALS research · 2020-01-30Clinical Trial Update: Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission [Phase 2, Phase 3]
A clinical trial evaluating Pyronaridine-artesunate with low-dose primaquine to prevent transmission of Plasmodium falciparum malaria (Phase…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Fetal Immunity to Falciparum Malaria
This clinical trial update reports a completed study investigating fetal immunity to Plasmodium falciparum malaria sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Malaria Prevalence in Children
A completed clinical trial update reporting malaria prevalence in children caused by Plasmodium falciparum, sponsored by NIAID.