Pertussis
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Safety of Tetanus, Diphtheria, Acellular Pertussis With 5 Acellular Pertussis Components (Tdap5) Vaccination During Pregnancy
This clinical trial update reports on the safety of the Tdap5 vaccine administered during pregnancy; the study is active but not currently r…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) [Phase 1]
A Phase I clinical trial update for an absorbed acellular pertussis–diphtheria–tetanus vaccine intended for adults and adolescents; the stud…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in Pregnancy [Phase 4]
Phase 4 clinical trial evaluating concurrent versus sequential administration of Tdap and an RSV vaccine in pregnant individuals.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine [Phase 1]
This is a Phase 1 clinical trial evaluating an adsorbed, acellular pertussis vaccine component combined with Hib and ACWY meningococcal comp…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis [Phase 1]
Phase 1 clinical trial update on establishing a controlled human infection model using pertactin-deficient Bordetella pertussis to study per…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: CARE-ID: Dynamics of Respiratory Infections in Children and Transmission in Households and Schools
The CARE-ID trial is currently recruiting to study dynamics of respiratory infections in children and transmission in households and schools…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Adults [Phase 3]
A Phase 3 clinical trial is evaluating the safety of a recombinant acellular pertussis vaccine in adults; the study is currently active but …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Pregnant Women
A clinical trial updating the safety assessment of a recombinant acellular pertussis vaccine in pregnant women; the study is currently activ…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed [Phase 3]
Phase 3 trial update for Beijing Institute of Biological Products' Diphtheria, Tetanus and Acellular Pertussis vaccine adsorbed; the study i…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Establishing a Controlled Human Infection Model of Bordetella Pertussis [Phase 1]
This clinical trial update notes completion of a Phase 1 study to establish a controlled human infection model of Bordetella pertussis.
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Adsorption of Cell-free Diphtheria and Tetanus (Three-component) Combined With Vaccine Phase III Clinical Trial [Phase 3]
Phase 3 clinical trial evaluating an adsorbed, three-component cell-free diphtheria-tetanus vaccine for prevention of pertussis, diphtheria,…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: A Phase I/II Study to Evaluate the Safety and Immunogenicity of GC3111B in Healthy Adults [Phase 1, Phase 2]
A Phase 1/2 clinical trial entry evaluating the safety and immunogenicity of GC3111B in healthy adults, with recruitment ongoing.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series [Phase 2, Phase 3]
Phase II/III trial update evaluating the immunogenicity, safety, and lot-to-lot consistency of LBVD, a fully liquid hexavalent DTaP-HepB-IPV…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: 10-year Follow-up After a Single Dose Acellular Pertussis Vaccination [Phase 4]
A Phase 4 clinical trial from Mahidol University is evaluating long-term outcomes 10 years after a single-dose acellular pertussis vaccinati…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Study of Concomitant Administration of the sIPV and DTaP or MMR [Phase 4]
Phase 4 trial evaluating concomitant administration of Sabin inactivated polio vaccine (sIPV) with DTaP or MMR vaccines; sponsored by the In…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Periscope Phase C Bordetella Pertussis Human Challenge Study With Delayed Antibiotic Therapy for 6 Weeks [NA]
This document provides an update on a Bordetella pertussis human challenge study evaluating delayed antibiotic therapy for six weeks; the tr…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above) [Phase 1]
This document provides a status update on a Phase 1 clinical trial of an adsorbed cell-free five-component DPT vaccine for people aged 6 yea…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: A Phase 4, Randomised Vaccination Study in Healthy Adults to Investigate the Effects of Acellular Pertussis Vaccine on Colonisation with Bordetella Pertussis Using Controlled Human Infection [Phase 4]
A Phase 4 randomized study in healthy adults to evaluate how acellular pertussis vaccine affects colonisation by Bordetella pertussis using …
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component) [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial of an adsorbed cell-free five-component DPT vaccine conducted by CanSino Biologics Inc. is currently active…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Pertussis Immunization During Pregnancy & HIV Infection
Clinical trial update on pertussis vaccination during pregnancy in women with HIV infection; the study is completed.
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Phase I/II, Open Label, Randomized, Safety and Immunogenicity Following DTwP-Hepatitis B-Hib-IPV Vaccine (Bio Farma) in Indonesian Infants [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 safety and immunogenicity study of a pentavalent DTwP-HepB-Hib-IPV vaccine in Indonesian infants; the t…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age [Phase 2]
Phase 2 trial to evaluate the immunogenicity of LR20062 versus control in healthy infants at 2, 4, and 6 months of age. The study targets pr…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: Safety and Immunogenicity of DTaP-IPV/Hib Pentavalent Vaccine in Chinese 2-month-old Infants [NA]
This clinical trial is evaluating the safety and immunogenicity of a pentavalent DTaP-IPV/Hib vaccine in 2-month-old Chinese infants; the st…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV [Phase 3]
This document reports a Phase 3 clinical trial evaluating the immunogenicity and safety of a hexavalent vaccine that contains a reduced-dose…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: The Optimal Timing of Vaccination in Pregnancy
This clinical trial update discusses ongoing studies to determine the optimal timing of pertussis vaccination during pregnancy. Recruitment …